English Product Name
| Brand | Jihepu |
|---|---|
| Origin | Shandong, China |
| Manufacturer Type | Authorized Distributor |
| Instrument Type | Benchtop Centrifugal Concentrator |
| Maximum Speed | 4000 rpm |
| Maximum Capacity | 62 × 1.5 mL |
| Temperature Range | Ambient to 55 °C (adjustable, heater optional) |
| Dimensions (W×D×H) | 500 × 490 × 280 mm |
| Rotor Configuration | Fixed-angle rotor standard |
| Vacuum Interface | External vacuum pump compatible (optional KC200102) |
| Cold Trap Compatibility | Yes (optional KC200101, −50 °C, 4 L capacity) |
Overview
The Jihepu ZL3 Series Vacuum Centrifugal Concentrator is an integrated benchtop system engineered for gentle, efficient solvent removal from heat-sensitive biological and analytical samples. It combines three orthogonal physical principles—centrifugal force, vacuum-induced boiling point depression, and controlled conductive heating—to achieve high-yield recovery of nucleic acids, proteins, peptides, metabolites, and small-molecule compounds without thermal degradation. Unlike conventional rotary evaporators or nitrogen blow-down systems, the ZL3 operates under reduced pressure while maintaining sample integrity through rotational stabilization and uniform thermal distribution across the rotor chamber. Its design adheres to core laboratory workflow requirements for reproducible concentration steps in downstream applications such as LC-MS sample preparation, enzymatic assay cleanup, and next-generation sequencing library normalization.
Key Features
- Intelligent microprocessor-based control system with large backlit LCD display for real-time monitoring of speed, temperature, vacuum status, and remaining time.
- Corrosion-resistant aluminum drying chamber with electrophoretic coating to withstand exposure to organic solvents including ethanol, acetone, acetonitrile, and ethyl acetate.
- Non-contact magnetic drive rotation mechanism eliminates mechanical wear, shaft seals, and lubrication requirements—ensuring long-term operational stability and zero contamination risk.
- Standard fixed-angle rotor accommodates up to 62 × 1.5 mL microcentrifuge tubes; optional rotors support 12 × 10 mL, 6 × 50 mL, or 6 × 250 mL configurations for scalable throughput.
- Translucent polycarbonate lid with safety interlock enables continuous visual inspection during operation while meeting IEC 61010-1 mechanical safety standards.
- Programmable timer ranging from 1 minute to 99 hours and 59 minutes, with automatic shutdown and audible alert upon cycle completion.
Sample Compatibility & Compliance
The ZL3 series supports a broad range of sample matrices—including aqueous buffers, volatile organic extracts, acidic or basic solutions—and maintains compatibility with common labware (e.g., PCR strips, LoBind tubes, glass vials). All wetted components comply with ISO 8573-1 purity class 4 for compressed air systems and are certified free of leachable heavy metals per USP and . When paired with the optional KC200101 cold trap (−50 °C, 4 L), condensation efficiency exceeds 95% for solvents with vapor pressures above 10 mbar at 25 °C. The system architecture permits integration into GLP- and GMP-regulated environments when configured with audit-trail-enabled software (see Software & Data Management section) and validated against ASTM E2500-13 and ISO/IEC 17025:2017 calibration protocols.
Software & Data Management
While the base ZL3 model operates via standalone hardware controls, optional firmware upgrades enable RS-232 or USB connectivity for remote parameter logging and method transfer. With third-party data acquisition platforms (e.g., LabArchives ELN, Thermo Fisher SampleManager), users can embed ZL3 run records—including timestamped setpoints, actual speed/temperature profiles, and vacuum decay curves—into electronic batch records. Full 21 CFR Part 11 compliance is achievable using external validation packages that enforce user authentication, electronic signatures, and immutable audit trails for all critical process parameters.
Applications
- Concentration and desalting of DNA/RNA prior to sequencing library construction
- Removal of residual trifluoroacetic acid (TFA) from peptide synthesis cleavage mixtures
- Preparative cleanup of reaction supernatants in medicinal chemistry workflows
- Stabilization of unstable metabolites during untargeted metabolomics sample preparation
- High-throughput evaporation of 96-well plate formats using compatible multi-channel rotor adapters
FAQ
What vacuum level is required for optimal performance?
A final chamber pressure of ≤0.1 mbar is recommended for rapid evaporation of common solvents; this is typically achieved using the optional KC200102 dual-stage diaphragm vacuum pump.
Can the ZL3 be used without heating?
Yes—the heater module is field-deactivatable, allowing ambient-temperature concentration for thermolabile analytes such as certain enzymes or labile post-translational modifications.
Is rotor balancing mandatory before each run?
Yes. Although the magnetic drive tolerates minor imbalance, precise mass symmetry across opposing positions is required to maintain rotor stability at 4000 rpm and prevent premature bearing fatigue.
Does the system include vacuum pump and cold trap by default?
No. Both the vacuum pump (KC200102) and cold trap (KC200101) are optional accessories selected based on solvent volatility, throughput volume, and laboratory infrastructure.
What maintenance intervals are specified for long-term reliability?
Annual verification of vacuum seal integrity, rotor surface inspection for microcracks, and calibration of temperature sensors against NIST-traceable references are advised per manufacturer’s service bulletin ZL3-SV-2023.
