HPE-12A Parallel Vacuum Centrifugal Concentrator
| Origin | Shandong, China |
|---|---|
| Manufacturer Type | Distributor |
| Origin Category | Domestic |
| Model | HPE-12A |
| Price Range | USD 14,000–28,000 |
| Instrument Type | Vacuum Centrifugal Concentrator |
| Temperature Range | Ambient +5°C to 100°C |
| Temperature Control Accuracy | ±0.5°C |
| Total Sample Capacity | 12 × 120 mL |
| Rotational Speed | 0–500 rpm |
| Orbit Diameter | 5 mm |
| Quantitative Endpoint Options | 0.5 mL or 1.0 mL per tube |
| Power Consumption | 1500 W |
| Net Weight | 32 kg |
| Dimensions (W×D×H) | 510 × 380 × 450 mm |
Overview
The HPE-12A Parallel Vacuum Centrifugal Concentrator is an engineered solution for high-throughput, reproducible solvent removal under controlled vacuum and thermal conditions. It operates on the principle of simultaneous centrifugal force, regulated heating, and dynamic vacuum application—enabling rapid evaporation while preventing sample bumping, foaming, or cross-contamination. Unlike nitrogen blow-down systems, the HPE-12A eliminates reliance on compressed gas infrastructure, reducing lab footprint and operational overhead. Its design targets laboratories performing routine batch processing in environmental monitoring (e.g., EPA Method 525.3, 8081B), pesticide residue analysis (AOAC 2007.01), pharmaceutical QC (USP & ICH Q5C), and metabolomics workflows where consistent endpoint volume recovery is critical. The instrument is fully compatible with standard 15 mL and 50 mL conical centrifuge tubes, as well as custom-format vessels up to 120 mL capacity per position.
Key Features
- Parallel processing of up to 12 samples simultaneously—each with independent vacuum-sealed lid and dedicated temperature-sensing feedback loop.
- Integrated gradient temperature control system enabling programmable ramp-and-hold profiles without manual intervention.
- Centrifugal rotation (0–500 rpm, 5 mm orbit) combined with heated aluminum block (ambient +5°C to 100°C) ensures uniform heat transfer and surface agitation for accelerated solvent removal.
- Automated quantitative endpoint detection at user-selectable volumes (0.5 mL or 1.0 mL), triggered by real-time pressure differential sensing and rotational torque monitoring.
- Closed-loop condensate recovery system with integrated cold trap; achieves >95% solvent capture efficiency for common organics (e.g., acetonitrile, methanol, ethyl acetate, dichloromethane).
- Compact footprint (510 × 380 × 450 mm) permits safe operation inside standard fume hoods—eliminating need for external venting or dedicated utility rooms.
- Dual-mode vacuum regulation: coarse vacuum via built-in diaphragm pump (ultimate vacuum ≤10 mbar), fine-tuned via optional external vacuum controller for method-specific pressure profiling.
Sample Compatibility & Compliance
The HPE-12A accommodates a broad range of sample matrices including aqueous extracts, organic-phase eluates, enzymatic digests, and cell lysates. Tube compatibility includes polypropylene, glass, and PTFE-lined screw-cap vials compliant with ISO 8573-1 (compressed air purity) and ASTM D4176 (centrifuge tube integrity standards). All wetted components meet USP Class VI biocompatibility requirements. The system supports GLP/GMP-aligned workflows through audit-trail-enabled operation logs (when paired with optional software module), and complies with IEC 61010-1 safety standards for laboratory electrical equipment. Vacuum and thermal parameters are traceable to NIST-calibrated reference instruments.
Software & Data Management
While the base unit features intuitive front-panel LCD interface with real-time display of temperature, vacuum level, RPM, and remaining time, optional PC-based software (HPE-Control Suite v3.2) provides full protocol management, remote monitoring, and electronic record retention. Software modules support 21 CFR Part 11-compliant user authentication, electronic signatures, and immutable audit trails—including event timestamps for start/stop, parameter changes, and endpoint detection. Export formats include CSV and PDF reports compatible with LIMS integration.
Applications
- Pre-concentration of water and soil extracts prior to GC-MS or LC-MS/MS analysis (e.g., EPA 1694, EN 15662).
- Parallel evaporation of QuEChERS extracts in food safety testing laboratories.
- Downstream processing in oligonucleotide synthesis and peptide purification workflows.
- High-volume sample preparation for clinical toxicology screening and forensic drug analysis.
- Method development for solvent exchange in nanoparticle formulation and polymer characterization.
FAQ
Is the HPE-12A suitable for acid-sensitive or thermolabile compounds?
Yes—its low-temperature vacuum evaporation capability (down to ambient +5°C) and absence of direct radiant heating minimize thermal degradation. Gradient temperature programming further supports gentle desolvation protocols.
Can it be integrated with existing laboratory vacuum networks?
Yes—the instrument accepts external vacuum line input (via standard 8 mm barbed port) and features automatic pressure modulation to maintain setpoint stability across variable network conditions.
What maintenance is required for long-term reliability?
Routine maintenance includes quarterly cleaning of the condensate chamber, annual calibration of temperature and pressure sensors using certified references, and replacement of vacuum pump oil every 500 operating hours.
Does it support unattended overnight operation?
Yes—fully programmable run cycles with auto-shutdown upon endpoint detection, over-temperature cut-off, and vacuum loss alarm ensure safe extended operation.
