Sartorius CPA223S Precision Balance

Overview

The Sartorius CPA223S Precision Balance is an ISO/GLP-compliant laboratory balance engineered for high-reproducibility mass measurement in routine analytical and quality control environments. Utilizing a patented monolithic weighing sensor architecture, the CPA223S delivers exceptional long-term stability and resistance to mechanical stress, thermal drift, and environmental vibration—critical performance attributes for regulated laboratories operating under GMP, GLP, or ISO 17025 frameworks. With a 220 g capacity and 1 mg readability, it bridges the functional gap between analytical and precision balances, supporting applications ranging from formulation checks and sample preparation to reference standard handling and small-part verification. Its internal motor-driven calibration system—isoCAL—is fully automated and temperature-compensated, executing full-range calibration and adjustment without manual intervention, thereby eliminating operator-induced error and ensuring traceable, audit-ready performance across shifts and extended operational cycles.

Key Features

• Monolithic electromagnetic force compensation (EMFC) sensor with integrated thermal stabilization for ≤ ±0.001 g repeatability and ≤ ±0.002 g linearity across the full 220 g range
• isoCAL: Fully automatic, temperature-triggered internal calibration and adjustment—no external weights required; supports scheduled or on-demand execution with full audit trail generation
• Backlit LCD display with 16 mm digit height—optimized for legibility under variable ambient lighting and glove-compatible operation
• RS-232C serial interface compliant with standard laboratory instrument protocols; enables bidirectional data exchange with PCs, LIMS, or peripheral devices such as the optional YDP03-0CE or YDP20-0CE printers
• Built-in application modes: percentage weighing, net totalization, animal weighing (with dynamic averaging), unit conversion (g, oz, ct, etc.), and piece counting—with configurable sample weight and tolerance settings
• Stainless steel pan (Ø 110 mm) mounted on a rigid, low-profile housing designed for chemical resistance and ease of cleaning; conforms to IP42 ingress protection for dust resistance

Sample Compatibility & Compliance

The CPA223S accommodates a broad spectrum of sample types—including powders, granules, liquids in tared vessels, and small solid components—within its 220 g limit and 110 mm pan diameter. Its robust mechanical design minimizes sensitivity to air currents and bench vibration, making it suitable for shared lab benches without dedicated anti-vibration tables. From a regulatory standpoint, the balance supports full ISO/IEC 17025 and GLP documentation requirements: all calibrations, weighings, and user actions can be timestamped, user-ID tagged, and exported with digital signatures when connected to compliant software or printers. isoCAL event logs meet FDA 21 CFR Part 11 criteria for electronic records when paired with validated Sartorius LabX or DataControl software configurations.

Software & Data Management

Data integrity is enforced via standardized RS-232C communication using ASCII-based command protocols compatible with third-party laboratory informatics systems. When interfaced with Sartorius LabX software (optional), the CPA223S enables automated method-driven workflows, real-time statistical process control (SPC), and full electronic signature support for audit-ready reporting. Standalone operation includes GLP-compliant printouts via YDP-series printers—each record contains balance ID, date/time stamp, operator ID (if configured), calibration status, measured value, uncertainty estimate, and environmental metadata (e.g., internal temperature reading). All internal memory stores up to 999 weighing events with timestamps, retrievable via serial dump or printer output.

Applications

• Pharmaceutical QC: Active pharmaceutical ingredient (API) dispensing, excipient ratio verification, and tablet weight uniformity pre-testing per USP <905>
• Chemical R&D: Catalyst dosing, reagent preparation, and stoichiometric mixture validation where 1 mg resolution ensures reproducible reaction outcomes
• Materials science: Density determination of small polymer samples, metal alloys, or ceramics using displacement or pycnometry workflows
• Food & beverage labs: Nutrient blend verification, additive concentration checks, and portion-weight compliance testing against Codex Alimentarius thresholds
• Educational labs: Teaching metrology fundamentals, uncertainty propagation, and ISO/IEC 17025 documentation practices using a production-grade platform

FAQ

Does the CPA223S support external calibration with certified weights?
Yes—while isoCAL provides full internal calibration, the balance accepts external calibration via standard Class M2 or better weights through the “External Cal” mode, enabling traceability to national metrology institutes.
Is GLP-compliant data export possible without LabX software?
Yes—the built-in RS-232C port supports direct ASCII data streaming to any terminal emulator or custom script; printer outputs include mandatory GLP fields (operator, time, calibration status, value) by default.
What is the warm-up time required for optimal accuracy?
The balance achieves thermal equilibrium and full specification performance within 30 minutes of power-on under stable ambient conditions (20–25 °C, <60% RH).
Can multiple users be assigned distinct access levels?
User management is handled externally via LabX or host-system authentication; the CPA223S itself supports operator ID entry (alphanumeric, up to 8 characters) for traceability in printed or exported records.
Is the isoCAL function compliant with ISO 9001:2015 clause 7.1.5.2?
Yes—isoCAL satisfies requirements for “monitoring and measurement resource verification”, including automatic recalibration at defined intervals or temperature deviations, with documented evidence of conformance available in the calibration log.