Cole-Parmer Masterflex® L/S Standard Brushless Digital Pump
| Brand | Masterflex |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | 77921-70 |
| Drive | L/S® Standard Brushless Digital Drive (07523-80) |
| Pump Head | L/S Easy-Load II (77200-62) |
| Tubing | Tygon® LFL L/S® 24 (06429-24, 10 ft) |
| Speed Range | 0.1–600 rpm |
| Max Flow Rate | 1700 mL/min |
| Min Flow Rate | 0.28 mL/min |
Overview
The Cole-Parmer Masterflex® L/S Standard Brushless Digital Pump is an engineered solution for precise, repeatable, and maintenance-free fluid handling in analytical laboratories, bioprocessing workflows, and quality control environments. Based on peristaltic pumping technology—where rollers compress flexible tubing to generate positive displacement—the system eliminates fluid contact with moving mechanical parts, ensuring contamination-free transfer of sensitive, abrasive, or shear-sensitive media. Its brushless DC motor architecture delivers stable torque across the full speed range, minimizing speed drift and enabling high reproducibility in volumetric delivery. Designed for integration into automated systems or standalone benchtop operation, this pump meets the operational rigor required in GLP-compliant labs and regulated manufacturing settings where traceability and consistent performance are non-negotiable.
Key Features
- Brushless digital drive with microprocessor-controlled feedback loop ensures ±0.2% speed stability over time and temperature variations
- Easy-Load II pump head (77200-62) enables single-handed tubing loading and alignment verification via visual window—reducing setup time and operator error
- Wide speed range of 0.1–600 rpm supports both ultra-low-flow applications (e.g., reagent dosing in HPLC mobile phase preparation) and high-throughput transfer (e.g., buffer circulation in bioreactor feed lines)
- Integrated digital display with rotary encoder knob allows intuitive local control; optional RS-232/RS-485 communication enables remote command via LabVIEW, Python, or PLC-based SCADA systems
- Compliance-ready design includes CE marking, UL/CSA certification, and RoHS-conformant materials—fully aligned with IEC 61000-6-2/6-4 electromagnetic compatibility standards
Sample Compatibility & Compliance
The pump accommodates standard L/S®-sized tubing, including chemically resistant Tygon® LFL L/S® 24 (06429-24), which exhibits low extractables, USP Class VI certification, and compatibility with aqueous buffers, organic solvents (e.g., ethanol, isopropanol), and mild acids/bases. Its sealed housing meets IP20 ingress protection requirements for dry laboratory environments. While not intrinsically safe, the drive unit is compatible with Class I, Division 2 hazardous location configurations when installed with appropriate barrier systems. Documentation packages support audit readiness under FDA 21 CFR Part 11 (with optional electronic log export), ISO/IEC 17025 method validation protocols, and ASTM D3418 for polymer melt flow characterization when used in extrusion feed calibration setups.
Software & Data Management
The drive operates natively without proprietary software but supports ASCII-based command protocols for seamless integration into existing lab informatics infrastructure. Time-stamped speed logs (sampled at 1 Hz) can be exported via serial interface for inclusion in ELN entries or LIMS batch records. Optional firmware upgrades provide enhanced event logging—including tubing wear alerts triggered by cumulative revolutions—and configurable analog output (0–10 VDC) for real-time flow proxy monitoring. All configuration parameters are stored in non-volatile memory, preserving user-defined presets after power cycling—a requirement for multi-shift operations under GMP Annex 11 guidelines.
Applications
- Continuous perfusion in cell culture bioreactors requiring stable, pulseless flow at ≤10 mL/min
- Automated sample dilution and standard addition in ICP-MS and AAS sample introduction systems
- Controlled reagent delivery in titration platforms and continuous flow chemistry reactors
- Buffer exchange and column equilibration in preparative chromatography workflows
- In-line pH or conductivity probe calibration using certified reference solutions at defined flow rates
FAQ
What tubing sizes are compatible with the L/S Easy-Load II pump head?
The head accepts L/S®-designated tubing only, including inner diameters from 0.125″ to 0.375″ (3.2–9.5 mm); recommended for use with Tygon® LFL L/S® 24 (ID: 0.25″) as supplied.
Does the pump support analog or digital I/O for process automation?
Yes—standard RS-232/RS-485 ports and optional 0–10 VDC analog input/output are available for closed-loop speed control or external trigger synchronization.
Is validation documentation available for regulated environments?
Factory test reports, IQ/OQ templates, and material compliance certificates (including USP Class VI and REACH) are provided upon request for installation qualification and operational qualification protocols.
How often does the tubing require replacement under continuous operation?
Typical service life for Tygon® LFL L/S® 24 at 300 rpm and ambient temperature is 500–800 hours; lifetime scales inversely with speed and pressure load—monitoring via visual inspection of compression zone deformation is advised.
Can the drive be mounted in a rack or integrated into a custom enclosure?
Yes—the chassis features standardized 19″ rack-mount flanges (optional kit 07523-85) and front-panel cutout dimensions compliant with NEMA-1 panel mounting specifications.
