HJ HSP-150ZD Temperature and Humidity Controlled Environmental Chamber

Overview

The HJ HSP-150ZD Temperature and Humidity Controlled Environmental Chamber is an upright, vertically configured laboratory-grade incubation system engineered for precise, long-term stabilization of biological and pharmaceutical samples under tightly regulated thermal and hygroscopic conditions. Designed in accordance with ISO 17025-aligned environmental chamber performance criteria and compatible with GLP-compliant workflows, the HSP-150ZD employs a dual-mode control architecture—combining PID-regulated heating with compressor-based refrigeration and steam-assisted humidification—to maintain stable setpoints across its operational envelope. Its forced-air convection system ensures uniform temperature distribution (±1.0 °C at 37 °C) and reproducible humidity profiles (50–95 %RH), making it suitable for applications requiring adherence to pharmacopoeial stability testing protocols (e.g., ICH Q1A–Q1E), microbial growth studies (ASTM D6329), and cell culture preconditioning where ambient drift must be minimized.

Key Features

• Mirror-polished SUS304 stainless steel interior chamber—non-porous, corrosion-resistant, and compliant with USP General Chapter <1058> requirements for equipment qualification in biopharmaceutical environments.
• Dual-door configuration: outer magnetic-sealed insulated door and inner full-view tempered glass door—optimized for visual monitoring without thermal/hygrometric disturbance.
• Hermetic R134a refrigeration circuit with automatic defrost cycle—eliminates manual intervention and prevents ice accumulation on evaporator surfaces during extended low-temperature operation.
• Intelligent safety architecture including over-temperature cutoff (independent of main controller), compressor thermal overload protection, and real-time fault diagnostics logged to internal memory.
• Programmable operation modes: timed start/stop, multi-step cycling, and power-loss recovery with retained setpoint and runtime data—supporting 21 CFR Part 11–compliant audit trails when integrated with validated data logging software.
• Modular shelf system with four-tier height adjustability and 15 kg load rating per shelf—designed for flexible arrangement of Petri dishes, flasks, multiwell plates, and small animal cages (up to juvenile rodent scale).

Sample Compatibility & Compliance

The HSP-150ZD accommodates diverse sample formats—including microbiological cultures (bacteria, fungi, yeast), mammalian and insect cell monolayers, plant seedlings, pharmaceutical dosage forms (tablets, capsules), and diagnostic reagents—within its 150 L working volume. Its operating range (0–50 °C / 50–95 %RH) aligns with common ICH stability zones (Zone IVb: 30 °C / 75 %RH; Zone III: 30 °C / 65 %RH) and supports accelerated aging per ASTM E1981. The chamber meets CE marking requirements for electrical safety (EN 61010-1) and electromagnetic compatibility (EN 61326-1). While not certified to UL 3101 or IEC 60068-2 series by default, its construction and control logic are fully compatible with IQ/OQ/PQ validation packages required for GMP-regulated laboratories.

Software & Data Management

Standard operation utilizes the embedded PID controller with LCD interface and tactile keypad navigation. Optional touchscreen upgrade enables intuitive graphical programming of multi-segment temperature/humidity ramps, dwell times, and alarm thresholds. Data output is available via RS-485 (Modbus RTU) for integration into centralized SCADA or LIMS platforms. When paired with HJ’s optional data logger (sold separately), the system records timestamped temperature and humidity values at user-defined intervals (1–60 min), generates CSV export files, and supports electronic signature functionality for FDA 21 CFR Part 11 compliance. All logged events—including door openings, alarm triggers, and controller resets—are time-stamped and non-erasable within the device’s onboard memory.

Applications

• Pharmaceutical stability testing per ICH guidelines (long-term, intermediate, and accelerated conditions)
• Bacterial and fungal culture maintenance under standardized incubation parameters (e.g., ISO 8573-1, CLSI M22-A2)
• Cell line expansion and passaging in controlled humidity to prevent media evaporation in open vessels
• Seed germination and plant tissue culture requiring photoperiod-independent environmental control
• Material testing of hygroscopic polymers, adhesives, and packaging films under defined moisture exposure
• Calibration verification of portable hygrometers and thermometers using traceable reference standards

FAQ

What is the minimum ambient temperature required for reliable sub-10 °C operation?
The unit requires ambient conditions below 26 °C to achieve and sustain setpoints below 10 °C. Operation in warmer rooms may result in insufficient cooling capacity and prolonged stabilization times.

Can the chamber operate continuously at 95 %RH across its full temperature range?
No. Humidification is only active between 10 °C and 30 °C. Below 10 °C, condensation risk and heater inefficiency preclude stable high-RH control; above 30 °C, the system prioritizes temperature regulation and disables humidification to prevent uncontrolled moisture accumulation.

Is external data logging supported out-of-the-box?
Yes—RS-485 Modbus RTU interface is standard. Third-party SCADA systems or HJ’s dedicated logging software can acquire real-time sensor data without hardware modification.

Are calibration certificates included with shipment?
Factory calibration reports (traceable to NIM China) are provided. Full ISO/IEC 17025-accredited calibration with uncertainty statements is available as an optional service prior to delivery.

What maintenance intervals are recommended for optimal performance?
Compressor oil inspection every 24 months; condenser coil cleaning every 6 months in dusty environments; humidifier tank descaling every 3 months using citric acid solution; door gasket integrity check quarterly.