FLUKO F30Z-581-S Inline High-Shear Dispersing & Homogenizing System
| Brand | FLUKO |
|---|---|
| Origin | Shanghai, China |
| Model | F30Z-581-S |
| Instrument Type | Probe-type Rotor-Stator Homogenizer |
| Dimensions (W×D×H) | 665×120×135 mm |
| Processing Capacity | 20 L |
| Power | 1050 W |
| Voltage/Frequency | 220 V, 50/60 Hz |
| Flow Rate (Water) | 1–20 L/min |
| Max. Viscosity | 1000 cP |
| Speed Range | 3500–25,000 rpm |
| Max. Operating Temperature | 120 °C |
| Standard Housing Material | SS304 |
| Standard Working Chamber | Stainless Steel (Unjacketed) |
| Standard Rotor-Stator Head | 25DG |
| Shaft Seal Materials | Silicon Carbide (SiC), FKM |
| Inlet/Outlet OD | 14 mm (Flexible Hose Connection) |
| Display | Analog Scale (F30Z) |
| Weight | ~7 kg |
Overview
The FLUKO F30Z-581-S is an inline high-shear dispersing and homogenizing system engineered for laboratory-scale simulation of continuous industrial processing conditions. Based on the proven rotor-stator principle—where a high-speed rotating element (rotor) shears fluid against a precisely machined stationary element (stator)—this system generates intense hydrodynamic cavitation, turbulent flow, and extensional deformation to achieve rapid particle size reduction, droplet breakup, and uniform phase dispersion. Unlike batch homogenizers, the F30Z-581-S operates in true inline mode, enabling continuous recirculation or single-pass processing without dead zones, making it ideal for process development, formulation optimization, and scalability studies from lab to pilot plant.
Key Features
- Robust 1050 W brushless motor delivering stable torque across the full speed range (3500–25,000 rpm), ensuring consistent shear intensity under variable load conditions.
- Modular rotor-stator configuration with interchangeable heads—including the standard 25DG geometry—optimized for fine emulsification (<1 µm droplet Dv90), nanoparticle dispersion, and colloidal stabilization.
- Inline architecture with 14 mm OD hose-compatible inlet/outlet ports allows seamless integration into closed-loop circulation systems or direct connection to feed tanks and downstream units.
- Stainless steel (SS304) housing and SS316L wetted components provide corrosion resistance and compatibility with aqueous, solvent-based, and mildly aggressive media up to 120 °C.
- High-integrity mechanical sealing using silicon carbide (SiC) faces and FKM elastomers ensures leak-free operation at elevated pressures and temperatures, meeting long-term reliability requirements for GLP-compliant workflows.
- Compact footprint (665 × 120 × 135 mm) and lightweight design (~7 kg) facilitate benchtop installation, mobile cart mounting, or integration into custom-built process skids.
Sample Compatibility & Compliance
The F30Z-581-S accommodates a broad spectrum of sample types—including oil-in-water and water-in-oil emulsions, polymer dispersions, pigment suspensions, pharmaceutical nanosuspensions, and biological cell lysates—within a viscosity envelope of up to 1000 cP. Its construction adheres to general principles outlined in ISO 8504-2 (mixing equipment safety) and supports alignment with Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) frameworks when deployed in regulated environments. While not certified for explosive atmospheres or sterile processing out-of-the-box, optional upgrades—including jacketed chambers for temperature control and enhanced surface finish (Ra ≤ 0.8 µm)—are available to support compliance with USP , ASTM D2887, and ISO 13320-based method validation protocols.
Software & Data Management
The base F30Z-581-S model features analog speed indication; the F30Z-D variant adds digital RPM readout with ±1% full-scale accuracy. For traceable operation, FLUKO offers optional analog 0–10 V or 4–20 mA speed output signals compatible with external PLCs or SCADA systems. Though no proprietary software is bundled, the device supports integration into LabVIEW™, MATLAB®, or custom Python-based acquisition platforms via third-party I/O modules. All operational parameters—including runtime, cumulative energy input (kWh), and thermal history—can be logged externally to meet audit requirements under FDA 21 CFR Part 11 when paired with validated electronic record systems.
Applications
- Formulation development of nanoemulsions for topical drug delivery and functional food ingredients.
- Rapid screening of surfactant efficacy and phase inversion behavior during emulsion preparation.
- Dispersion of carbon nanotubes, graphene oxide, or metal oxide nanoparticles in polymer matrices.
- Cell disruption and organelle isolation in bioprocessing R&D, particularly where heat-sensitive biomolecules require minimal thermal exposure.
- Viscosity-controlled homogenization of high-solid-content battery slurry precursors prior to coating trials.
- Scale-down modeling of industrial inline homogenizers (e.g., APV, Silverson, or IKA systems) for DOE-driven process mapping.
FAQ
Can the F30Z-581-S be used for sterile applications?
Sterility is not inherent to the base configuration; however, autoclavable SS316L working chambers and SIP-compatible seals are available as factory options upon request.
What maintenance intervals are recommended for the mechanical seal?
Under typical aqueous use at ≤80 °C and ≤15,000 rpm, SiC/FKM seals exhibit service life exceeding 1,500 operating hours; inspection is advised every 500 hours in abrasive or high-viscosity service.
Is flow rate adjustable independently of rotor speed?
No—the unit lacks integrated flow control; flow modulation must be achieved externally via variable-speed feed pumps or bypass valves to maintain optimal shear rate (γ̇ = k × N) across varying viscosities.
Does FLUKO provide IQ/OQ documentation support?
Yes—customized Installation Qualification (IQ) and Operational Qualification (OQ) templates, aligned with ISO/IEC 17025 and ASTM E2500, can be supplied upon order confirmation.
Can the 25DG head be replaced with other geometries?
Yes—FLUKO offers a family of interchangeable rotor-stator heads (e.g., 15DG for low-volume precision, 30DG for higher throughput), all mechanically compatible with the F30Z drive shaft and housing interface.
