Shanghai RightOne LHS-100CL Low-Temperature Temperature and Humidity Controlled Chamber

Overview

The Shanghai RightOne LHS-100CL is a vertically oriented, air-cooled temperature and humidity controlled chamber engineered for precise environmental simulation in laboratory and quality assurance settings. It operates on the principle of forced-air convection with dual independent control loops—one for refrigeration/heating and one for humidification/dehumidification—enabling stable, reproducible maintenance of defined thermal and hygrometric conditions. Designed for long-term stability under continuous operation, the chamber supports applications requiring strict adherence to storage or testing protocols for biologics, pharmaceuticals, electronic components, and polymer materials. Its operational envelope spans -40 °C to +80 °C and 30–95 %RH, making it suitable for accelerated aging studies, stability testing per ICH Q1 guidelines, and cold-chain validation workflows.

Key Features

• Microprocessor-based PID control system with 5.7-inch backlit LCD interface; supports up to 99 programmable cycles, each with 30 configurable segments (max duration per segment: 99 h 99 min)
• Double-door structure featuring an inner tempered glass observation window sealed with silicone gasketing, minimizing thermal leakage while enabling real-time visual monitoring without chamber disturbance
• Interior chamber constructed from electropolished mirror-finish stainless steel (SUS304), with fully rounded corners and adjustable stainless steel shelving (2 standard / up to 14 optional shelves)
• Eco-friendly refrigerant R134a/R406a compliant with Montreal Protocol standards; high-efficiency scroll compressor paired with optimized finned-tube evaporator and condenser
• Integrated steam-generation humidification system using stainless steel immersion heating elements and auto-refillable built-in water reservoir, coupled with Vaisala HUMICAP®-based relative humidity sensor (calibration traceable to NIST standards)
• Asymmetric air duct design with rear-mounted centrifugal blower ensures uniform airflow distribution, achieving ≤±0.5 °C spatial temperature deviation and ≤±3 %RH humidity deviation across the working volume (measured at 5 standardized points per IEC 60068-3-5)
• Four-position castor assembly with dual-locking mechanism (two swivel + two fixed leveling feet) for secure positioning and safe relocation

Sample Compatibility & Compliance

The LHS-100CL accommodates a broad range of sample types—including cryopreserved plasma units, lyophilized vaccines, semiconductor wafers, elastomeric seals, and coated optical substrates—without risk of condensation-induced degradation or thermal shock. Its chamber geometry (450 × 380 × 590 mm) permits placement of ISO-standard 500 mL blood bags, USP -compliant packaging trays, and ASTM D4332-conditioned test specimens. The unit meets essential requirements of GB/T 10586–2018 (Chinese national standard for environmental test chambers), and its control architecture supports audit-ready data logging when equipped with optional RS485/USB interface and compliant software. While not pre-certified to FDA 21 CFR Part 11, the system’s programmable logic, password-protected parameter modification, and timestamped event logging provide foundational infrastructure for GLP/GMP-aligned validation.

Software & Data Management

When configured with the optional USB/RS485 communication module and proprietary Shanghai RightOne Environmental Control Software (v3.2+), the LHS-100CL enables remote monitoring, real-time graphing of temperature/humidity profiles, and export of CSV-formatted datasets compatible with JMP, MATLAB, and LIMS platforms. The software implements user-level access control (administrator/operator modes), automatic calibration log archiving, and alarm history with cause-code tagging (e.g., “Compressor Overheat”, “Humidifier Dry-Run”). All logged parameters include millisecond-resolution timestamps and are stored with SHA-256 hash integrity verification—facilitating traceability during regulatory inspections or internal QA audits.

Applications

• Long-term storage of clinical biospecimens (e.g., PBMCs, serum aliquots) at -25 °C ±2 °C per CAP/CLIA requirements
• ICH Q5C stability assessment of monoclonal antibody formulations across multiple climate zones (Zone IVb: 30 °C/75 %RH; Zone III: 30 °C/65 %RH)
• Thermal cycling validation of automotive ECUs per ISO 16750-4 specifications
• Moisture absorption testing of polyamide 66 components per ASTM D5229/D570
• Pre-conditioning of printed circuit boards prior to solder paste reflow per IPC-J-STD-033
• Accelerated corrosion testing of zinc-plated fasteners under cyclic damp heat (IEC 60068-2-30)

FAQ

What is the maximum allowable ambient temperature for reliable operation?
The chamber is rated for use in environments ≤30 °C and ≤70 %RH (non-condensing). Operation above these limits may reduce cooling capacity and extend recovery time after door opening.
Can the unit maintain -40 °C while simultaneously holding 30 %RH?
Yes—low-temperature dehumidification is achieved via chilled-mirror condensation and desiccant-assisted drying; full specification compliance is verified at all combinations within the stated ranges.
Is third-party calibration certification available?
Shanghai RightOne provides factory calibration reports (NIST-traceable probes); accredited on-site calibration by CNAS-certified labs can be arranged separately.
What safety protections are integrated?
Dual independent over-temperature cutoffs (mechanical + electronic), compressor high-pressure cutout, humidifier dry-run protection, door-open alarm with audible/visual alert, and optional independent over-temperature alarm module (add-on part #LHS-ALM-01).
How often does the internal water reservoir require refilling during continuous 95 %RH operation?
At nominal 95 %RH setpoint and 25 °C, the 4.2 L reservoir supports approximately 72 hours of uninterrupted humidification before manual refill; usage scales inversely with target RH and temperature.