METTLER TOLEDO MA104 Analytical Balance
| Brand | METTLER TOLEDO |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | MA104 Analytical Balance |
| Price | Upon Request |
Overview
The METTLER TOLEDO MA104 Analytical Balance is a precision laboratory instrument engineered for high-accuracy mass measurement in routine analytical and quality control environments. Operating on electromagnetic force compensation (EMFC) principle, the MA104 delivers stable, drift-free readings with resolution down to 0.1 mg across its 104 g maximum capacity. Designed for ISO/IEC 17025-compliant laboratories, it integrates proven transducer architecture and temperature-compensated electronics to maintain metrological integrity under typical lab conditions (20–25 °C, <60% RH). Its compact footprint and front-access design support integration into fume hoods, clean benches, and regulated QC workstations without compromising accessibility or ergonomic workflow.
Key Features
- Electromagnetic force compensation sensor with automatic internal calibration using built-in test weights — activated manually or scheduled via time-based triggers
- High-contrast, backlit LCD display (128 × 64 pixels) with dynamic on-screen guidance for step-by-step weighing, tare, and unit conversion
- Intuitive touch-sensitive keypad with tactile feedback — supports glove-compatible operation and minimizes surface contamination risk
- Dual-interface connectivity: RS232 serial port for legacy printers and LIMS integration; USB-A host port for direct connection to USB flash drives or PC-based data acquisition software
- Robust mechanical construction featuring stainless steel pan, draft shield-compatible design (optional accessory), and impact-resistant ABS housing rated IP42 for dust resistance
- Auto-zero tracking and dynamic damping algorithms ensure rapid stabilization (<2 s) even after sample placement or environmental fluctuation
Sample Compatibility & Compliance
The MA104 accommodates standard analytical samples up to 104 g, including powders, granules, liquids in tared containers, and small solid specimens. Its open pan geometry allows compatibility with volumetric flasks, crucibles, and weigh boats commonly used in pharmaceutical assay, chemical synthesis, and materials testing workflows. The balance meets OIML R76-1 Class I accuracy requirements for analytical balances and conforms to relevant clauses of ASTM E898 (Standard Guide for Use of Analytical Balances), USP “Weights and Balances”, and ISO 9001 documentation traceability standards. Internal calibration records—including date, time, operator ID (if configured), and deviation values—are stored in non-volatile memory and exportable via USB for GLP/GMP audit readiness.
Software & Data Management
Data handling is optimized for regulatory compliance and operational efficiency. Weighing results can be exported in CSV or TXT format directly to USB storage devices without intermediate software. When connected to a Windows-based system, the balance is recognized as a virtual COM port, enabling seamless integration with METTLER TOLEDO LabX Lite (freeware) or third-party LIMS/ELN platforms supporting ASCII-based serial protocols. All data transmissions include timestamp, net/gross/tare values, unit identifier, and stability confirmation flag. Optional password-protected user accounts support role-based access control for calibration, configuration, and data export functions—aligning with FDA 21 CFR Part 11 principles where electronic signatures and audit trails are required.
Applications
The MA104 serves as a primary weighing instrument in pharmaceutical QC labs for active pharmaceutical ingredient (API) dispensing, excipient ratio verification, and dissolution tablet weight uniformity testing per USP . It is routinely deployed in academic research for stoichiometric reagent preparation, gravimetric analysis (e.g., sulfate precipitation), and catalyst loading in heterogeneous catalysis studies. Industrial applications include incoming raw material inspection in fine chemical manufacturing, formulation batch record generation in cosmetics R&D, and moisture content pre-weighing prior to LOD determination. Its repeatability (≤0.05 mg standard deviation at full load) and linearity performance support method validation under ICH Q2(R2) guidelines.
FAQ
What is the readability and maximum capacity of the MA104?
The MA104 offers 0.1 mg readability with a 104 g maximum capacity.
Does the MA104 support external calibration with traceable weights?
Yes — it accepts external calibration using Class E2 or better certified砝码, with calibration parameters stored in device memory and logged in the internal audit trail.
Can the MA104 be integrated into a networked laboratory environment?
While it lacks Ethernet or Wi-Fi, its RS232 and USB-A interfaces enable reliable point-to-point integration with PCs, printers, and USB mass storage—sufficient for most decentralized QC settings.
Is the MA104 compliant with pharmacopeial requirements for balance qualification?
It satisfies the core performance criteria outlined in USP , EP 2.1.6, and JP 2.03 when operated within specified environmental limits and subjected to documented periodic verification per IQ/OQ/PQ protocols.
How often does the internal calibration need to be performed?
Calibration frequency depends on usage intensity and environmental stability; METTLER TOLEDO recommends initiation after power-on, following temperature shifts >2 °C, or at user-defined intervals (e.g., every 2–4 hours in high-throughput labs).


