Berthold
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| Brand | Berthold |
|---|---|
| Origin | Germany |
| Model | LB9508 |
| Instrument Type | Electrochemiluminescence Analyzer |
| Automation Level | Fully Automated |
| Detector | Ultra-High-Speed, Low-Noise Photon-Counting Photomultiplier Tube (PMT) |
| Wavelength Range | 280–630 nm |
| Detection Sensitivity | <1 amol ATP |
| Sample Introduction | JET Injection Technology |
| Compatible Tube Formats | 12 × 75 mm, 12 × 55 mm, 12 × 47 mm luminometer tubes |
| Injection Volume Range | 10–100 µL or 25–300 µL per channel |
| Injection Accuracy | >98% |
| Software | ICE Operating System with Wizard-Based Interface |
| Brand | Berthold |
|---|---|
| Origin | Germany |
| Model | LB983 |
| Imaging Modality | Bioluminescence & Fluorescence Optical Imaging |
| Camera Type | Cooled Slow-Scan CCD |
| Cooling Method | Peltier (−90 °C typical operating temperature) |
| Spectral Range | 400–900 nm |
| Pixel Resolution | Up to 3.2 MP (NC320 front-illuminated) / 1.0 MP (NC100 back-illuminated) |
| Field of View Adjustment | Motorized vertical camera positioning (35–725 mm travel) |
| Maximum Sample Height | 260 mm |
| Dark Box Light Tightness | < 0.001 lux internal ambient light leakage |
| Calibration | Integrated optical flat-field and intensity reference standard for quantitative cross-experiment comparability |
| PET Integration | MACU interface module with dedicated software synchronization for small-animal PET co-registration |
| Software Platform | IndiGO v5.x with FDA 21 CFR Part 11-compliant audit trail, GLP/GMP-ready reporting modules |
| Brand | Berthold |
|---|---|
| Origin | Germany |
| Model | Mithras² LB 943 |
| Function Type | Multimode |
| Automation Level | Semi-Automatic |
| Assay Methods | Endpoint, Kinetic, Long-Term Kinetic, Well-Scanning |
| Curve Fitting | Linear, Non-Linear, Logarithmic |
| Detector Types | PMT (3), Photodiode (1) |
| Wavelength Range | 200–850 nm (standard), up to 1000 nm (optional) |
| Absorbance Range | 0–4 OD |
| Absorbance Linearity | <0.1% |
| Wavelength Accuracy | ±1 nm |
| Precision (CV) | <0.3% |
| Luminescence Sensitivity | <2 amol ATP/well (96-well, Glow) |
| Fluorescence Sensitivity | <0.1 fmol Fluorescein/well (96-well) |
| TRF Sensitivity | <2 amol Europium/well (96-well) |
| HTRF® Dynamic Range | >600% ΔF |
| FP Sensitivity | <4 mP |
| AlphaScreen® Detection Limit | <12 ng |
| Crosstalk | <5×10⁻⁶ |
| Excitation Sources | Halogen lamp, Xenon flash lamp, Laser (optional) |
| Monochromator | Dual grating (excitation & emission), bandwidth 4–22 nm adjustable in 1 nm steps, optical density >10⁶ |
| Reading Modes | Top & Bottom Read (all modalities) |
| Plate Formats | 6–1536-well microplates, Petri dishes, Terasaki plates |
| Temperature Control | Ambient +5 °C to 45 °C (optional) |
| Certifications | CE, UL, CSA |
| Power Supply | 110–240 V AC, 50/60 Hz |
| Brand | Berthold |
|---|---|
| Origin | Germany |
| Model | NightOwl II LB 983 |
| CCD Sensor | Back-illuminated, deep-depletion CCD, 1 MP (13 × 13 µm pixels) |
| Cooling | −90 °C (Peltier) |
| Full Well Capacity | 100,000 e⁻ |
| Spectral Range | 350–1050 nm |
| Quantum Efficiency | >90% @ 500–700 nm |
| Lens | f/0.95, C-mount, 25 mm |
| Field of View | Adjustable 35–725 mm |
| Exposure Time | 30 ms to >120 h |
| Sample Height Capacity | 312 mm |
| Binning | 1×1 to 16×16 |
| Filter Wheel | 6-position, 340–1100 nm |
| Excitation Source | ≥75 W halogen lamp (340–750 nm) |
| X-ray Module | Optional integrated micro-radiography |
| Anesthesia Interface | 5-animal isoflurane chamber with flow control |
| Dimensions (H×W×D) | 122 × 60 × 40 cm |
| Weight | 85 kg |
| Compliance | CE-marked, GLP/GMP-ready architecture, FDA 21 CFR Part 11–compatible software audit trail |
| Brand | Berthold |
|---|---|
| Origin | Germany |
| Model | LB 985N |
| Resolution | 1024 × 1024 |
| Pixel Size | 13.3 µm |
| Sensor Type | Cooled EMCCD |
| Cooling Temperature | −20 °C (absolute) |
| Quantum Efficiency Peak | 500–750 nm |
| Imaging Modes | Bioluminescence, Chemiluminescence, Fluorescence (with GFP filter set) |
| Dual-Camera Configuration | Top-view + side-view |
| Stage | Motorized X-Y stage with 360° rotational capability |
| Environmental Control | Integrated temperature and humidity regulation |
| Software | indiGO™ control and analysis suite |
| Brand | Berthold |
|---|---|
| Origin | Germany |
| Model | LB985 |
| Imaging Modality | Optical Bioluminescence & Fluorescence Imaging |
| Detector | 12-Megapixel Cooled EMCCD (–20 °C operating temperature) |
| Quantum Efficiency Peak | 500–750 nm |
| Imaging Modes | Bioluminescence/Chemiluminescence (LULu), Ultra-Low-Noise CCD (IKLu), Dual-Mode Bioluminescence + Fluorescence (LUFlu) |
| Illumination | LED-based Simulated Sunlight (Top Illumination), Side Illumination Module |
| Sample Stage | Motorized X-Y Translation + 360° Rotational Platform |
| Environmental Control | Integrated Temperature & Humidity Regulation |
| Software | indiGO™ v6.x with Hardware Synchronization, Audit Trail, and GLP-Compliant Data Archiving |
| Brand | Berthold |
|---|---|
| Origin | Germany |
| Model | Tristar² S LB 942 |
| Detection Modes | Absorbance, Luminescence, Fluorescence (top/bottom read), Time-Resolved Fluorescence (TRF), Homogeneous Time-Resolved Fluorescence (HTRF®), Fluorescence Polarization (FP), Bioluminescence Resonance Energy Transfer (BRET/BRET²/NanoBRET), Fluorescence Resonance Energy Transfer (FRET) |
| Detector | Low-noise, high-speed single-photon counting PMT and photodiode |
| Absorbance Range | 0–4 OD |
| Absorbance Linearity | <0.1% |
| Wavelength Accuracy | ±1 nm |
| Wavelength Scanning Speed | 0.1 s per data point |
| Absorbance Precision | <0.3% |
| Luminescence Sensitivity | <6 amol ATP/well (96-well, glow assay) |
| Fluorescence Sensitivity | <0.2 fmol fluorescein/well (96-well) |
| TRF Sensitivity | <5 amol europium/well |
| Dynamic Range | >6 decades |
| Well-to-Well Crosstalk | <5×10⁻⁶ |
| Injector Options | Up to 3 programmable injectors (10–100 µL, 1 µL increment) |
| Temperature Control | Ambient +5 °C to 45 °C (optional) with cooled PMT |
| Compatible Plate Formats | 6–384-well microplates, Eppendorf µPlate GO.5, Terasaki plates, Petri dishes |
| Excitation Source | Xenon flash lamp |
| Monochromator | Dual grating (4–22 nm bandwidth, 1 nm increment) for absorbance/fluorescence excitation |
| Filter Capacity | Up to 30 high-transmission (>80%) interference filters (excitation & emission) |
| Software | ICE™ (Instrument Control & Evaluation), compliant with 21 CFR Part 11 audit trail and electronic signature requirements |
| Certifications | CE, RoHS, ISO 13485–aligned design |
| Operating Environment | 15–35 °C, 10–85% RH (non-condensing) |
| Storage | 0–40 °C |
| Power Supply | 110–240 V AC, 50/60 Hz |