BOXUN BXP-65 Electrically Heated Constant-Temperature Incubator
| Brand | BOXUN |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | BXP-65 |
| Price Range | USD 700–1,400 (FOB) |
| Temperature Control Range | RT+5°C to 100°C |
| Temperature Uniformity | ±0.6°C (at 60°C) |
| Humidity Range | Not Humidified (Dry Air Operation) |
| Chamber Capacity | 65 L |
| External Dimensions (L×W×H) | 555 × 550 × 720 mm |
| Internal Dimensions (L×W×H) | 410 × 350 × 450 mm |
| Heating Recovery Time (to 60°C) | 14 min |
| Temperature Fluctuation (at 60°C) | ±0.3°C |
| Ramp Time to 60°C | 16 min |
| Rated Power | 0.55 kW |
| Standard Shelves | 2 pcs (max. 5 pcs) |
| Control System | PID Analog Regulation |
| Programmability | 10 segments × 100 cycles |
| Timer Range | 0–99 h 59 min |
| Fan Speed Stages | 5-step adjustable |
| Communication Interface | Standard RS-485 port |
| Optional Accessories | Thermal Printer (domestic or Epson OEM), GPRS SMS Alert Module, FDA/GMP-Compliant Monitoring Software, Wireless Temperature Data Logger (validated up to 130°C, with calibration certificate at 0°C, 60°C, 121°C), GLP/GMP Audit Trail Support |
Overview
The BOXUN BXP-65 Electrically Heated Constant-Temperature Incubator is an entry-level, convection-driven laboratory incubator engineered for precise thermal control in microbiological culture, enzyme activity assays, cell maintenance, and stability testing under dry ambient conditions. Unlike humidified or CO₂-capable incubators, the BXP-65 operates as a forced-air, non-humidified thermal chamber—making it suitable for applications where moisture condensation, microbial contamination risk, or vapor-phase interference must be avoided. Its heating system employs rear-mounted resistive elements with directional airflow design: heated air enters the working chamber directly from the rear wall, minimizing thermal stratification and enabling rapid stabilization. The chamber’s internal geometry—including strategically placed perforations in the rear and side panels—ensures laminar, uniform air circulation across the full 65 L volume. Temperature regulation relies on a dual-sensor architecture: a primary Pt100 RTD sensor feeds real-time feedback to a PID analog controller, while an independent mechanical overtemperature cutoff switch provides fail-safe redundancy. This dual-protection scheme meets IEC 61010-1 requirements for Class II laboratory equipment safety.
Key Features
- High-resolution LCD interface displaying setpoint, actual chamber temperature, operational status, fan speed level, and program progress in real time
- Rear-wall heating configuration with direct airflow injection—reducing average ramp time to 60°C to ≤16 minutes and recovery time after door opening to ≤14 minutes
- 5-stage programmable fan speed control, allowing users to optimize airflow velocity for sensitive samples (e.g., low-convection cell monolayers) or rapid thermal equilibration
- 10-segment × 100-cycle programmable temperature profile capability, supporting multi-step incubation protocols without manual intervention
- Dual overtemperature protection: electronic (RTD-based) + electromechanical (bimetallic switch), compliant with EN 61010-2-010 safety clauses for incubators
- Standard RS-485 serial interface (Modbus RTU protocol) for integration into centralized lab monitoring networks
- Structural design optimized for GLP/GMP readiness: stainless steel interior (SUS304), rounded corners, smooth welds, and removable shelves for cleaning validation
Sample Compatibility & Compliance
The BXP-65 accommodates standard microbiological and biochemical sample formats including Petri dishes (up to 150 mm), test tubes (16 × 150 mm), flasks (Erlenmeyer up to 1 L), and multiwell plates (6–96-well). Its non-humidified operation eliminates condensation-related artifacts in long-term storage of desiccation-sensitive reagents or lyophilized standards. The unit complies with ISO 13485 manufacturing quality systems and supports traceable calibration per ISO/IEC 17025 when paired with validated wireless loggers. Optional FDA-compliant monitoring software provides 21 CFR Part 11–enabled audit trails, electronic signatures, and user-access tiering. GMP version includes SOP-linked alarm escalation, deviation logging, and electronic batch record export (CSV/PDF). Calibration certificates (NIST-traceable) are available for three-point validation (0°C, 60°C, 121°C)—essential for sterilization process qualification and PQ documentation.
Software & Data Management
The optional BOXUN FDA/GMP Monitoring Software runs on Windows OS and connects via RS-485 or USB-to-485 adapter. It enables continuous acquisition of temperature data at configurable intervals (1–60 sec), automatic alarm generation (SMS/email/GUI), and dynamic graphing with overlay comparison across multiple units. All data entries include timestamps, operator ID, and device signature—enabling full ALCOA+ compliance (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available). The GPRS SMS alert module transmits fault codes (e.g., “OVTEMP”, “FAN_FAIL”, “COMM_LOST”) directly to up to five pre-registered mobile numbers. Wireless temperature loggers (optional) feature onboard memory (≥32,000 points), Bluetooth 5.0 sync, and export to CSV, PDF, or XML for IQ/OQ/PQ reporting. Data analysis tools include statistical summaries (mean, SD, max/min), trend line fitting, and pass/fail thresholds aligned with USP or ISO 14644-3.
Applications
- Microbiological incubation: bacterial growth (E. coli, S. aureus), fungal culture, endotoxin testing (LAL assay warm-up)
- Enzyme kinetics studies requiring stable thermal environments between 30–80°C
- Accelerated stability testing per ICH Q1A(R3) guidelines (e.g., 40°C/75% RH simulated via dry-heat stress at 60°C)
- Pre-incubation of PCR master mixes, restriction digests, and antibody conjugation reactions
- Material aging tests for pharmaceutical packaging components (e.g., HDPE vials, blister foil)
- Calibration verification of thermocouples, RTDs, and portable dataloggers using fixed-point references
FAQ
Is the BXP-65 suitable for cell culture applications requiring CO₂ or humidity control?
No. The BXP-65 is a dry, forced-air incubator without CO₂ regulation or humidity generation. It is intended for non-living or moisture-tolerant biological samples.
Can the unit be validated for GxP environments?
Yes—when equipped with the GMP software package and calibrated wireless logger, it supports IQ/OQ/PQ execution per ASTM E2500 and EU Annex 15 requirements.
What is the maximum operating temperature for optional accessories like the wireless logger?
The certified wireless temperature logger is validated for continuous operation up to 130°C, with calibration points at 0°C, 60°C, and 121°C.
Does the incubator support remote monitoring via Ethernet or Wi-Fi?
No native Ethernet/Wi-Fi; however, third-party RS-485-to-Ethernet gateways can be deployed to integrate into building management systems (BMS) or LabVantage platforms.
Are shelf load limits specified for thermal uniformity compliance?
Yes—uniformity specifications (±0.6°C) are guaranteed with ≤2 standard shelves loaded at ≤70% capacity. Full shelf loading (5 shelves) requires recalibration per ISO 14644-3 Annex B.
