CM-12 Water Bath Nitrogen Evaporator by Chengmengweiye

Overview

The CM-12 Water Bath Nitrogen Evaporator is a precision-engineered sample concentration system designed for laboratories requiring reproducible, low-temperature solvent removal under inert atmosphere. It operates on the principle of gentle nitrogen gas sweeping across the surface of heated liquid samples—accelerating evaporation while minimizing thermal degradation, oxidation, or analyte loss. Unlike dry-block evaporators, the water bath provides superior temperature homogeneity and buffering capacity, ensuring stable thermal conditions across all 12 sample positions. Engineered for routine QC/QA workflows in regulated environments, the CM-12 delivers consistent performance from ambient +5 °C up to 99 °C, with digital PID control achieving ±0.5 °C stability at 60 °C and ≤±0.5 °C uniformity across the bath. Its modular architecture supports seamless integration into GLP-compliant laboratories where traceability, repeatability, and method robustness are critical.

Key Features

• 12-position circular stainless steel water bath with independent digital temperature control and large backlit LCD display (0.1 °C resolution)
• Individually height-adjustable stainless steel gas needles (100 mm standard length, 200 mm vertical travel) for optimal positioning above diverse vessel geometries
• Per-channel flow regulation via Japan-made SMC precision needle valves—enabling fine-tuned nitrogen delivery (0–15 L/min total, ~330 mL/min per port, adjustable)
• Spring-loaded, numbered sample rack with universal tube clamping (Φ10–29 mm); compatible with test tubes, centrifuge tubes, conical vials, and culture tubes (1–50 mL capacity)
• Full solvent-resistant construction: 304 stainless steel bath, food-grade SMC silicone tubing (odorless, non-leaching), and corrosion-resistant aluminum support frame
• Dry-run protection circuit with thermal cutoff and dual-mode alarm (audible + visual) to prevent heater damage during low-water conditions
• Designed for safe operation inside chemical fume hoods—meets ventilation interface requirements for chlorinated, aromatic, or halogenated solvent evaporation
• Compact footprint (390 × 300 × 850 mm) and lightweight chassis (9.5 kg) facilitate benchtop deployment in high-density lab spaces

Sample Compatibility & Compliance

The CM-12 accommodates a broad range of sample containers without adapter kits: standard 13–18 mm round-bottom test tubes, 15–50 mL conical centrifuge tubes, 20 mL scintillation vials, and narrow-neck extraction vessels. Its open-bath geometry allows unrestricted access for pipetting, vortexing, or post-concentration handling. From a regulatory standpoint, the instrument complies with general electrical safety standards (IEC 61010-1) and is suitable for use in environments governed by ISO/IEC 17025, USP , and EPA Method 508/525 series workflows. While not inherently 21 CFR Part 11 compliant (as it lacks embedded audit trail or user authentication), its analog-digital hybrid control system permits external validation protocols—including calibration record linkage, SOP-defined temperature ramp verification, and periodic performance qualification (PQ) using NIST-traceable thermistors.

Software & Data Management

The CM-12 operates as a standalone hardware platform with no proprietary software dependency. All operational parameters—including setpoint temperature, real-time bath reading, and elapsed heating time—are displayed locally on the integrated LCD panel. For laboratories requiring electronic data capture, the unit features a 0–5 V analog output port (optional configuration) compatible with third-party data loggers (e.g., Omega OM-DAQPRO, Testo 176 T4) for continuous temperature trending and CSV export. Users may implement manual logbook entries aligned with ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) during routine maintenance and calibration checks. Firmware updates are not applicable; mechanical and thermal calibration intervals are recommended every 6 months per ISO/IEC 17025 Clause 6.4.10.

Applications

• Residue Analysis: Pesticide multiresidue screening in fruits, vegetables, cereals, and plant matrices per AOAC 2007.01 and EN 15662
• Pharmaceutical Testing: Residual solvent removal in API purification, herbal extract concentration, and dissolution media preparation per USP
• Environmental Monitoring: Pre-concentration of PAHs, PCBs, organochlorines, and phthalates from aqueous extracts (drinking water, wastewater, soil leachates) prior to GC-MS analysis
• Clinical & Forensic Toxicology: Plasma/urine sample cleanup for LC-MS/MS quantification of drugs of abuse, metabolites, and biomarkers
• Food Safety: Dioxin/furan pre-concentration in dairy fat, fish oil, and infant formula extracts per EU Regulation 2022/2445
• Material Science: Solvent exchange in nanoparticle synthesis and polymer solution casting protocols requiring inert, low-shear concentration

FAQ

Is the CM-12 certified for use in GMP-regulated environments?
The CM-12 is not supplied with formal GMP certification, but its design—stainless steel wetted parts, traceable temperature control, and dry-run safety—supports qualification under Annex 15 and ICH Q7. Users must perform IQ/OQ/PQ per internal SOPs.

Can I connect the unit to a centralized nitrogen supply line?
Yes. The inlet accepts standard φ7 mm OD tubing and supports input pressure up to 0.2 MPa. A dedicated inline pressure regulator and particulate filter are recommended upstream.

What maintenance is required for long-term reliability?
Monthly descaling of the bath with 10% citric acid solution; biannual inspection of silicone tubing for cracking; annual verification of temperature accuracy using a calibrated PT100 probe.

Does the instrument support programmable temperature ramps?
No. It maintains a single user-defined setpoint. For multi-stage evaporation protocols, external timers or sequential manual adjustment is required.

Are replacement gas needles and tubing available as consumables?
Yes. OEM-compatible stainless steel needles (100 mm, 150 mm, and custom lengths) and SMC silicone tubing (φ3 × φ6 mm) are stocked and shipped globally.