DRETOP ZYC-100BR Low-Temperature Incubated Orbital Shaker

Overview

The DRETOP ZYC-100BR Low-Temperature Incubated Orbital Shaker is an engineered platform for precise temperature-controlled agitation of biological and biochemical samples under defined thermal and mechanical conditions. Utilizing orbital shaking motion—generated via a robust three-dimensional eccentric cam drive—the instrument ensures uniform mixing while minimizing shear stress on sensitive cell cultures, microbial suspensions, and enzymatic reaction mixtures. Its integrated refrigeration system enables stable operation down to 4 °C, making it suitable for cold-sensitive applications including protein expression, low-temperature fermentation, and cryopreservation-related assays. Designed to meet the operational rigor of GLP-compliant laboratories, the ZYC-100BR conforms to fundamental requirements for reproducible incubation and agitation in life science workflows, supporting ISO 13485-aligned bioprocess development and ASTM E2500-13 guidelines for equipment qualification.

Key Features

• Brushless DC motor with wide-speed range (0–300 rpm) and ±1 rpm speed stability; maintenance-free operation with constant torque delivery across full load spectrum.
• PID-controlled microprocessor system with backlit LCD interface; real-time display of setpoint and actual values for temperature (resolution: 0.1 °C) and rotational speed.
• Stainless steel chamber interior and vibration platform; electrostatically coated exterior housing for corrosion resistance and ease of decontamination.
• Optimized startup algorithm prevents abrupt acceleration, reducing sample splashing and cross-contamination risk during initiation of oscillation.
• Integrated safety architecture includes over-temperature cutoff, over-speed shutdown, audible/visual alarm triggers, and encrypted parameter lockout to prevent unauthorized configuration changes.
• Optional UV-C irradiation module (254 nm) enables periodic sterilization of internal air and surfaces—critical for long-duration microbial culture or aseptic cell expansion protocols.

Sample Compatibility & Compliance

The ZYC-100BR accommodates standard laboratory vessels—including Erlenmeyer flasks (up to 2000 mL), test tubes, microtiter plates, and custom bioreactor vessels—via interchangeable clamping systems (fixed bottle holders, universal spring clips, and modular rack adapters). Its 450 × 410 mm platform supports heterogeneous loading configurations without compromising thermal uniformity. The unit complies with IEC 61010-1:2010 for electrical safety in laboratory equipment and meets ambient noise emission limits per ISO 7779. When configured with optional CO₂ or illumination modules (on related ZYC-series models), it supports USP and ISO 13408-1 requirements for controlled-environment cell culture systems.

Software & Data Management

While the base ZYC-100BR operates via standalone hardware controls, its optional USB data logging interface enables traceable acquisition of time-stamped temperature and speed profiles. Exported CSV files are compatible with LIMS integration and support 21 CFR Part 11–compliant audit trails when paired with validated third-party software. Firmware supports parameter memory retention across power cycles, ensuring protocol fidelity during routine use. For labs requiring enhanced data governance, optional PC-based control software provides remote monitoring, multi-user access levels, and electronic signature capture for critical parameter modifications.

Applications

This shaker serves core functions across academic research, pharmaceutical QC, and industrial biotechnology settings. Typical use cases include aerobic bacterial cultivation (e.g., E. coli expression at 37 °C), yeast fermentation kinetics studies, hybridization buffer equilibration, antibody purification column equilibration, and low-temperature enzyme activity assays. Its extended cold range supports cold-adapted psychrophilic organism studies and stabilization of thermolabile recombinant proteins during purification. In environmental microbiology, it facilitates standardized BOD testing and soil suspension homogenization per EPA Method 1681.

FAQ

What is the minimum operating temperature of the ZYC-100BR?
The unit achieves and maintains temperatures from 4 °C to 60 °C, verified per IEC 60068-3-5 thermal stability testing protocols.
Is the shaker compatible with sterile tissue culture workflows?
Yes—when equipped with UV sterilization and optional HEPA-filtered air exchange, it supports ISO Class 5–7 cleanroom-compatible operations.
Can the device store multiple user-defined protocols?
Up to 10 independent programs can be saved with password-protected access, including ramp rates, dwell times, and alarm thresholds.
Does the ZYC-100BR support regulatory compliance documentation?
Factory-supplied IQ/OQ documentation packages are available upon request, aligned with GAMP 5 principles and suitable for FDA submission contexts.
What maintenance intervals are recommended?
Annual calibration verification of temperature and speed sensors is advised; brushless motor requires no scheduled servicing beyond routine visual inspection and chamber cleaning.