EYELA N-1300D-W Rotary Evaporator

Overview

The EYELA N-1300D-W Rotary Evaporator is an engineered solution for efficient, reproducible solvent removal and concentration of heat-sensitive samples in research and quality control laboratories. Designed under the rigorous standards of Tokyo Rikakikai Co., Ltd. (EYELA), this unit implements classical rotary evaporation principles—combining controlled vacuum, regulated bath heating, precise rotational motion, and optimized condensation geometry—to achieve high recovery yields while minimizing thermal degradation. Its compact footprint and modular architecture support integration into multi-instrument workflows common in pharmaceutical development, natural product isolation, polymer synthesis, and analytical sample preparation. The system operates on the principle of reducing solvent boiling point via vacuum application while maintaining stable vapor pressure gradients across the evaporative surface and condenser interface.

Key Features

• Dual-side flask mounting mechanism enables rapid left/right positioning of round-bottom flasks without tooling—ideal for sequential processing or comparative evaporation trials.
• Continuous 180 mm vertical lift with smooth linear actuation ensures consistent immersion depth control and accommodates variable flask geometries up to 3 L capacity when equipped with the optional reinforced shaft.
• Rotatable circular base allows unrestricted angular orientation of the evaporation assembly, facilitating ergonomic access and alignment with auxiliary equipment such as cold traps or vacuum controllers.
• Heated water bath delivers uniform thermal energy across the flask surface, with digital PID regulation maintaining temperature stability within ±1 °C over the full 20–90 °C operating range (ambient start).
• Vacuum-compatible glassware set includes a 3 L evaporation flask, 1 L receiving flask, and a vertical dual-coil condenser offering 1200 cm² effective cooling surface area—optimized for high-efficiency reflux and low-backpressure operation at 0.08 MPa ultimate vacuum.
• Brushless DC motor provides quiet, maintenance-free rotation across 10–310 rpm with programmable ramp profiles and real-time speed feedback.

Sample Compatibility & Compliance

The N-1300D-W supports standard borosilicate glassware conforming to ISO 3585 and ASTM E438 Type I Class A specifications. It is compatible with common organic solvents (e.g., acetone, ethyl acetate, dichloromethane, methanol) and aqueous mixtures used in extraction, purification, and lyophilization feedstock preparation. While not certified for GMP manufacturing environments per se, its construction and control architecture align with GLP documentation requirements—including traceable temperature logging, vacuum monitoring, and manual parameter recording. Users implementing SOP-driven workflows may integrate external data loggers compliant with FDA 21 CFR Part 11 for audit-ready electronic records.

Software & Data Management

This model operates via an integrated front-panel controller with LED display and tactile membrane keys—designed for reliability in non-networked lab settings. No proprietary software is required; however, analog output ports (0–10 V) are provided for connection to third-party SCADA systems or centralized lab monitoring platforms. Temperature and rotation setpoints are manually entered and retained through power cycles. For laboratories requiring enhanced traceability, optional RS-485 interfaces (sold separately) enable Modbus RTU communication with LIMS or ELN systems for automated parameter capture and event logging.

Applications

• Concentration of crude extracts in phytochemistry and metabolomics workflows.
• Solvent exchange prior to NMR or MS analysis to eliminate interfering volatiles.
• Removal of reaction solvents following Grignard, Suzuki, or esterification reactions.
• Preparative-scale dehydration of thermolabile APIs during early-phase formulation studies.
• Recovery of volatile flavor compounds in food science applications.
• Parallel evaporation setup when paired with multi-position bath accessories (not included).

FAQ

Is the N-1300D-W suitable for use with corrosive solvents such as concentrated HCl or HF?
No. Standard glassware and PTFE seals are not rated for strong mineral acids or hydrofluoric acid. Use only with solvents compatible with borosilicate 3.3 glass and fluoropolymer gaskets.
Can the unit be operated under inert gas atmosphere?
Yes—via optional gas inlet adapter (EYELA part no. N-1300-GAS), enabling nitrogen or argon purging during evaporation to prevent oxidation of sensitive compounds.
What maintenance intervals are recommended for long-term reliability?
Inspect vacuum tubing and seals every 6 months; clean condenser coils quarterly; verify bath fluid level and purity before each use; calibrate temperature sensor annually using a NIST-traceable reference thermometer.
Does the system include vacuum pump and chiller?
No. These are ancillary components selected based on application-specific vacuum requirements and condensation load. EYELA recommends pairing with oil-free diaphragm pumps (e.g., EYELA C20B) and recirculating chillers capable of −20 °C outlet temperature.
Is CE or UL certification available for this model?
The N-1300D-W manufactured in Shanghai meets IEC 61010-1 safety requirements and carries CCC certification for domestic Chinese markets. CE marking applies only to units assembled and tested at EYELA’s Tokyo facility; UL listing is not currently held.