EZONE CHEMIST Flow Path Module
| Brand | EZONE CHEMIST |
|---|---|
| Origin | Guangdong, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | Flow Path Module (Accessory) |
| Pricing | Upon Request |
| Material | 316L Stainless Steel |
| Components | Check Valve, Safety Relief Valve, Digital Mass Flow Controller (Gas), Digital Pressure Transducer, Tubing |
| Pressure Range | 0–100 bar |
Overview
The EZONE CHEMIST Flow Path Module is an engineered fluidic subsystem designed for integration into continuous flow chemistry platforms. It operates on the principle of controlled, segmented, and pressure-regulated delivery of reagents—enabling precise stoichiometric management in liquid–liquid, gas–liquid, and multi-component (e.g., A + B + C → P) reaction sequences. Unlike batch-based systems, this module supports steady-state operation under elevated backpressure, minimizing residence time distribution and enhancing reproducibility across synthetic campaigns. Its modular architecture allows seamless coupling with commercial microreactors, tube reactors, and packed-bed catalytic systems—making it suitable for both laboratory-scale process development and scalable pilot studies.
Key Features
- Pressure-rated construction using ASTM A240 316L stainless steel tubing and fittings, ensuring corrosion resistance against organic solvents, acidic/basic media, and reactive gases (e.g., H₂, O₂, Cl₂, NH₃).
- Integrated safety-critical components: ASME-certified spring-loaded safety relief valve (set point adjustable within 85–95% of max rated pressure), non-return check valve with ≤0.5 bar cracking pressure, and redundant pressure monitoring via calibrated digital transducers.
- Gas mass flow control compliant with ISO 14040/14044 life-cycle assessment protocols; features thermal-mass-based measurement with NIST-traceable calibration for gases including N₂, Ar, CO, CO₂, and CH₄.
- Real-time digital pressure readout (0–100 bar full scale) with ±0.25% FS accuracy and 0.1 bar resolution, supporting closed-loop pressure regulation when interfaced with external PID controllers.
- Standardized 1/4″ VCR and 1/8″ Swagelok end connections, compatible with industry-standard flow reactor manifolds (e.g., Vapourtec R-Series, Syrris Asia, Uniqsis Gemini).
Sample Compatibility & Compliance
The Flow Path Module accommodates a broad range of chemically aggressive reagents and multiphase mixtures without degradation or leaching. It has been validated for use with halogenated solvents (CH₂Cl₂, CHCl₃), polar aprotic media (DMF, DMSO), aqueous acids/bases (up to 6 M HCl or NaOH), and gaseous reagents at up to 100 bar. All wetted surfaces meet USP Class VI biocompatibility requirements. The assembly complies with PED 2014/68/EU for pressure equipment (Category IV), and its safety valve conforms to EN ISO 4126-1. Documentation includes material traceability certificates (EN 10204 3.1), pressure test reports (hydrostatic at 150 bar), and RoHS/REACH declarations.
Software & Data Management
While the module itself is hardware-only, its digital pressure transducer and gas mass flow controller support analog (4–20 mA) and digital (RS-485 Modbus RTU) outputs. These signals are natively compatible with LabVIEW, MATLAB Data Acquisition Toolbox, and industrial SCADA systems. When deployed in regulated environments (e.g., pharmaceutical process validation), data logging can be configured to meet FDA 21 CFR Part 11 requirements—including electronic signatures, audit trails, and user-access controls—via third-party acquisition software such as DeltaV or Ignition SCADA. Calibration records are stored in CSV/Excel format with timestamps and operator IDs.
Applications
- High-pressure hydrogenation reactions (e.g., nitro reduction, alkene saturation) with inline H₂ dosing and backpressure regulation.
- Photochemical transformations requiring inert gas purging and O₂ exclusion via continuous N₂ sweep.
- Exothermic nitrations and diazotizations where precise reagent addition rate and temperature coupling are critical.
- Multi-step telescoped syntheses involving incompatible intermediates (e.g., Grignard formation followed by electrophilic quench), enabled by sequential valve-triggered segment isolation.
- Process analytical technology (PAT) integration: paired with inline FTIR or UV-Vis flow cells for real-time conversion monitoring under steady-state conditions.
FAQ
Is the Flow Path Module certified for use in explosion-hazardous areas (ATEX/IECEx)?
No—this module is not intrinsically safe nor ATEX-certified. It must be installed in non-classified zones or housed within certified enclosures if used with flammable gases.
Can the pressure range be extended beyond 100 bar?
The standard configuration is rated to 100 bar. Custom variants with 150 bar rating are available upon engineering review and require upgraded fittings and transducer selection.
Does EZONE CHEMIST provide installation support or system integration services?
Yes—application engineers offer remote commissioning assistance, P&ID review, and compatibility verification with existing flow reactor platforms.
Are spare parts (e.g., replacement safety valves or flow sensors) available separately?
All components—including ASME-certified relief valves, calibrated mass flow elements, and 316L tubing kits—are stocked and supplied with individual calibration certificates.
What is the typical lead time for custom-configured modules?
Standard units ship within 5 business days; custom configurations (e.g., alternate gas calibrations, special port threading) require 3–4 weeks from order confirmation.
