Fritsch ANALYSETTE 22 Micro Tec² Laser Particle Size Analyzer
| Origin | Germany |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Micro Tec² |
| Pricing | Upon Request |
Overview
The Fritsch ANALYSETTE 22 Micro Tec² is a high-precision laser diffraction particle size analyzer engineered for rigorous laboratory and industrial quality control environments. Based on the ISO 13320 standard for laser diffraction methodology, it employs dual-wavelength laser illumination (532 nm green and 940 nm infrared) with Class 1 laser safety certification per EN 60825-1 (equivalent to IEC 60825-1), ensuring operator safety without requiring special protective infrastructure. Its optical architecture features an inverted Fourier design — a patented configuration in which the sample cell moves automatically during measurement to maximize scattering angle coverage across the full detector array. This arrangement enhances resolution, particularly for sub-micron particles (<1 µm), by capturing forward- and backward-scattered light with minimal angular truncation. The system is designed for both dry dispersion (via integrated or optional pneumatic disperser) and wet dispersion (using recirculating liquid module), supporting broad material classes including fragile agglomerates, cohesive powders, emulsions, and suspensions.
Key Features
- Inverted Fourier optical layout with motorized, auto-positioning sample cell for extended angular detection range and improved small-particle resolution
- Dual-laser source: 532 nm (7 mW) green diode laser and 940 nm (9 mW) infrared laser — optimized for refractive index contrast across diverse materials
- 57-channel detector array with orthogonal polarization orientation (vertical + horizontal) to resolve anisotropic scattering signatures
- Integrated automatic beam alignment system ensures long-term optical stability and eliminates manual recalibration
- Compact footprint enabled by reflective optics (folded beam path), reducing bench space requirements without compromising optical path length
- Dry dispersion unit compliant with ISO 14644-1 Class H cleanroom specifications (≤100 particles/m³ ≥0.5 µm)
- Modular SOP-driven operation: individual modules (e.g., sonication, dispersion pressure, measurement duration) can be enabled/disabled independently per sample type
Sample Compatibility & Compliance
The ANALYSETTE 22 Micro Tec² accommodates solids, slurries, emulsions, and aerosols via interchangeable dispersion units — including gravity-fed dry powder feeder, forced-air jet disperser, and recirculating wet module with ultrasonic bath or probe. Sample volume ranges from 0.1 mL (micro-wet) to >10 g (dry bulk). All measurements adhere to ISO 13320:2020 for diffraction-based particle sizing, with built-in validation protocols for obscuration, signal-to-noise ratio, and Mie theory parameter selection (refractive index, absorption coefficient). Instrument qualification documentation supports GLP/GMP workflows, and audit trails comply with FDA 21 CFR Part 11 requirements when used with validated software configurations. Background subtraction algorithms reduce dependency on ultra-pure water — tap water is acceptable for routine wet measurements after system priming.
Software & Data Management
The proprietary Fritsch MaS Control software provides intuitive workflow navigation, real-time scatter pattern visualization, and customizable reporting templates. It includes preconfigured SOP libraries covering common material categories (e.g., metal oxides, pharmaceutical excipients, battery cathode powders), each with optimized dispersion energy, measurement time, and refractive index presets. Raw intensity data, Mie-corrected size distributions (volume-, surface-, and number-based), D10/D50/D90 statistics, and span values are exportable in CSV, PDF, or XML formats. Database management supports multi-user access control, versioned method storage, and electronic signature capability for regulated environments. Software updates are delivered via secure Fritsch portal with release notes traceable to IEC 62304-compliant development lifecycle.
Applications
This analyzer serves R&D laboratories and production QA/QC departments in pharmaceuticals (API crystallinity assessment, inhaler formulation), advanced ceramics (sintering behavior prediction), battery materials (anode/cathode slurry homogeneity), catalyst development (pore structure correlation), food science (starch granule integrity), and environmental monitoring (sediment grain classification). Its ability to rapidly switch between dry and wet modes — combined with low sample consumption and automated cleaning cycles — enables high-throughput batch analysis while maintaining inter-day reproducibility ≤2% RSD for D50 across repeated measurements of NIST-traceable standards.
FAQ
What particle size range does the ANALYSETTE 22 Micro Tec² cover?
The instrument measures from 0.08 µm to 2000 µm using Mie theory-based inversion algorithms optimized for both monomodal and multimodal distributions.
Is the system compliant with regulatory documentation requirements?
Yes — when configured with validated software and operated under defined SOPs, it supports 21 CFR Part 11 compliance, including electronic signatures, audit trails, and data integrity controls.
Can the same instrument handle both fragile and abrasive samples?
Yes — adjustable dispersion energy (air pressure, sonication amplitude, stirrer speed) and multiple inlet options allow tailoring of mechanical stress to preserve sample integrity or achieve full deagglomeration.
How is optical alignment maintained over time?
An internal reference photodiode and closed-loop motorized mirror system perform automatic beam centering before each measurement cycle, eliminating drift-related calibration drift.
Does the system require deionized water for wet measurements?
No — background correction routines compensate for minor impurities; filtered tap water is sufficient for most routine applications after initial system flush.
