Grant PRS-10 Precision Orbital Shaking Platform
| Brand | Grant |
|---|---|
| Origin | United Kingdom |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | PRS-10 |
| Temperature Range | Ambient to 100 °C |
| Temperature Accuracy | ±1 °C |
| Heating Time to 100 °C | ≤1 min |
| Platform Size | 290 × 290 mm |
| Orbit Diameter | 20 mm |
| Speed Range | 50–300 rpm |
| Speed Accuracy | ±2 rpm |
| Load Capacity | 3 kg |
| Power Supply | 100–240 V AC, 50/60 Hz |
Overview
The Grant PRS-10 Precision Orbital Shaking Platform is an engineered laboratory instrument designed for controlled, uniform mixing of samples under regulated thermal conditions. Unlike basic incubator shakers or static heating blocks, the PRS-10 integrates a thermally stable metal heating plate with a precisely calibrated orbital shaking mechanism—enabling simultaneous temperature control and gentle, reproducible agitation. Its operation is based on the principle of orbital motion (20 mm diameter), which generates consistent fluidic shear and suspension homogeneity without vortexing or splashing. This makes it particularly suitable for applications requiring both thermal equilibration and mechanical mixing—such as enzyme kinetics assays, cell culture maintenance during incubation, solubility testing, and reagent preparation in QC laboratories.
Key Features
- Integrated orbital shaking and precise surface heating in a single compact platform—eliminates need for separate incubators or hot plates.
- Heated aluminum platform (290 × 290 mm) with rapid thermal response: reaches 100 °C in ≤1 minute and maintains stability within ±1 °C across the entire surface (verified per ISO 17025-compliant calibration protocol).
- Digital PID temperature control with real-time display and programmable ramping profiles; speed adjustable from 50 to 300 rpm in 1 rpm increments, with ±2 rpm repeatability over extended operation.
- Robust construction featuring corrosion-resistant anodized aluminum housing, reinforced stainless-steel support frame, and non-slip silicone mat interface for secure vessel placement.
- Compliance-ready design: includes configurable logging interval (1–60 s), onboard data storage (≥10,000 points), and USB export capability for audit-trail generation—supporting GLP/GMP documentation requirements.
Sample Compatibility & Compliance
The PRS-10 accommodates standard laboratory vessels including microtiter plates (96-/384-well), conical tubes (15–50 mL), centrifuge tubes, glass vials, and custom jigs for multi-position racks. Its uniform heat distribution (±0.8 °C max deviation at 100 °C, measured per ASTM E220) ensures reliable thermal performance across heterogeneous sample loads. The device conforms to IEC 61010-1:2010 for electrical safety and electromagnetic compatibility (EMC Class B). It supports traceable calibration via NIST-traceable reference thermometers and is compatible with external validation protocols required by FDA 21 CFR Part 11 for electronic records in regulated environments.
Software & Data Management
No proprietary software installation is required for basic operation; all parameters are configured via the front-panel touchscreen interface. For advanced data handling, the optional GrantLink™ PC application enables remote monitoring, real-time graphing, alarm threshold configuration, and CSV-formatted export of time-stamped temperature/speed logs. All logged data include operator ID fields, timestamp metadata, and checksum verification—ensuring integrity for regulatory submissions. Audit trails record parameter changes, session start/stop events, and calibration interventions, satisfying ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available).
Applications
- Accelerated stability studies (ICH Q1A–Q5C) requiring synchronized thermal stress and agitation.
- Pre-incubation of PCR master mixes and immunoassay reagents to ensure complete dissolution and homogenization prior to analysis.
- Standardized extraction protocols (e.g., EPA Method 3550C) where solvent-based analyte recovery depends on consistent orbital mixing at elevated temperatures.
- Cell-based assay preparation—including suspension culture conditioning and antibody conjugation steps—where temperature-sensitive biomolecules require controlled thermal environment during mixing.
- Calibration of viscosity standards using rotational rheometers, where temperature-controlled homogenization precedes shear-rate profiling.
FAQ
Does the PRS-10 support programming of multi-step temperature and speed profiles?
Yes—up to 10 user-defined segments can be stored, each with independent setpoints for temperature, speed, duration, and ramp rate.
Can the platform be used without shaking—i.e., as a standalone heated block?
Yes. Shaking can be disabled independently while maintaining full temperature control functionality.
Is the unit compatible with CO₂ incubators or glove boxes?
The PRS-10 is not rated for humidified or CO₂-enriched atmospheres; it is intended for ambient laboratory use only.
What calibration documentation is provided with shipment?
Each unit ships with a factory calibration certificate (traceable to UKAS-accredited standards), including verification data at 37 °C, 60 °C, and 100 °C.
How is overload protection implemented?
Thermal cutoff switches and current-limiting circuitry automatically deactivate heating and shaking if load exceeds 3 kg or internal temperature exceeds 110 °C.
