Hanuo TYMR-IIIA 7-Roll Digital Blood Mixer

Overview

The Hanuo TYMR-IIIA 7-Roll Digital Blood Mixer is a precision-engineered laboratory roller mixer designed specifically for gentle yet effective homogenization of viscous and sediment-prone biological samples. Unlike orbital shakers or vortex mixers, this device employs a dual-mode motion architecture—simultaneous rolling and rocking—based on controlled eccentric rotation of seven parallel cylindrical rollers. This mechanical configuration generates low-shear, laminar displacement across the entire length of sample tubes placed horizontally on the rollers, ensuring uniform mixing without foaming, hemolysis, or particle aggregation. The instrument operates exclusively at ambient temperature and is optimized for applications requiring prolonged, reproducible agitation—particularly in clinical diagnostics, blood bank operations, and quality control laboratories where sample integrity and protocol consistency are critical under ISO 15189 and CLIA-compliant workflows.

Key Features

• 7-roller horizontal platform with synchronized rotational symmetry, minimizing torque imbalance and mechanical wear over extended operation cycles
• Dual-motion capability: independent adjustment of rolling speed (20–80 rpm) and rocking oscillation frequency (20–80 cycles/min), enabling method-specific optimization for diverse sample viscosities
• Digital LED timer with 1-minute resolution and continuous mode selection—supports unattended operation up to 59 minutes with automatic power cutoff
• Stable base design with non-slip silicone feet and reinforced ABS housing, engineered for vibration-dampened performance on standard lab benches
• Low-power 15 W brushless DC motor ensures thermal stability and long-term reliability; no internal heating elements or cooling systems required
• Compact footprint (394 × 266 × 98 mm) facilitates integration into biosafety cabinets, cold rooms, or high-density instrument racks

Sample Compatibility & Compliance

The TYMR-IIIA accommodates standard anticoagulant tubes (EDTA, citrate, heparin), serum separator tubes (SST), cryovials (up to 15 mL), and dry-powder reagent vials (1–10 mL). Its 22 mm ±1 mm amplitude ensures consistent tube contact pressure across all seven rollers, eliminating slippage during agitation. The device complies with IEC 61010-1:2010 for electrical safety in laboratory equipment and meets EMC directive 2014/30/EU. While not certified for GMP manufacturing environments, it supports GLP-aligned documentation when used with traceable calibration logs and operator training records. It is routinely deployed in laboratories adhering to CAP-accredited protocols for whole blood QC material reconstitution and pre-analytical sample handling per CLSI H20-A3 guidelines.

Software & Data Management

This is a standalone hardware-only instrument with no embedded microcontroller-based data logging or PC connectivity. All operational parameters—including elapsed time, selected speed, and mode—are displayed via a 3-digit LED interface. For auditability in regulated settings, users are advised to integrate external timestamped logbooks or LIMS-linked manual entry workflows. No firmware updates or software validation packages are provided; however, the fixed-function design inherently satisfies FDA 21 CFR Part 11 requirements for “non-electronic record” devices—eliminating the need for electronic signature controls or audit trail configuration.

Applications

• Homogenization of whole blood, plasma, and serum specimens prior to automated hematology or coagulation analysis
• Reconstitution of lyophilized calibrators, controls, and diagnostic reagents without introducing air bubbles or denaturation
• Pre-analytical mixing of EDTA-anticoagulated samples for flow cytometry or molecular testing workflows
• Uniform dispersion of insoluble additives (e.g., stabilizers, preservatives) in diagnostic assay buffers
• QC batch verification of mixing efficacy using standardized dye diffusion assays per ISO 13485 Annex C

FAQ

Is the TYMR-IIIA suitable for use inside a refrigerated environment?
Yes—the device has no temperature-sensitive electronics or lubricants; it operates reliably between 4 °C and 35 °C ambient conditions.
Can it accommodate 50-mL conical tubes?
No—maximum supported tube diameter is 18 mm (e.g., standard 10–15 mL vacutainers); larger formats require custom roller adapters not supplied with the unit.
Does the mixer meet ISO 17025 calibration requirements?
The unit does not include factory-calibrated speed sensors; users must perform periodic verification using an external tachometer per ISO/IEC 17025 Clause 6.5.2.
Is there a CE marking on the device?
Yes—CE marking is affixed to the rear panel, confirming conformity with EU Machinery Directive 2006/42/EC and Low Voltage Directive 2014/35/EU.
What maintenance is required?
Annual visual inspection of roller surface integrity and motor mounting bolts is recommended; no scheduled lubrication or filter replacement is necessary due to sealed bearing construction.