Ismatec ISM931C Advanced Peristaltic Pump

Overview

The Ismatec ISM931C Advanced Peristaltic Pump is an engineered solution for precise, low-pulse fluid handling in analytical laboratories, bioprocessing workflows, and quality control environments. Based on the well-established peristaltic principle—where fluid is conveyed through flexible tubing via sequential compression by rotating rollers—the ISM931C employs a planetary gear motor drive to deliver exceptional flow stability and extended tube life. Unlike conventional gearmotors, the planetary architecture minimizes torque ripple and mechanical vibration, directly reducing pulsation amplitude and mitigating fatigue-induced tube failure. This design enables reproducible delivery across its full operational range—from ultra-low flows of 0.002 mL/min up to 44 mL/min—making it suitable for applications demanding high volumetric fidelity, such as reagent dosing in HPLC sample introduction, cell culture media perfusion, or continuous titration systems.

Key Features

• Planetary gear motor drive ensures smooth rotation and <1% flow variation over time, supporting GLP-compliant documentation requirements.
• Eight stainless-steel rollers mounted on precision-ground shafts provide uniform occlusion and consistent compression force across the entire pump head circumference.
• Dual-channel Click’n’go™ cassette system allows rapid, tool-free pump tube exchange with repeatable positioning—critical for multi-step assays or routine maintenance in regulated labs.
• Four-digit LED display offers real-time visibility of setpoint and actual parameters; intuitive keypad navigation supports standalone operation without external software.
• Five programmable operating modes: Flow Rate (mL/min), Time (s/min/h), Batch (number of cycles), Drip-Free (prevents post-dispense dripping), and Volume (µL/mL dispensed).
• Remote interface compatibility via RS-232 or optional analog I/O enables integration into automated platforms, SCADA systems, or LIMS-controlled workflows.

Sample Compatibility & Compliance

The ISM931C accommodates standard dual-channel peristaltic tubing sizes (e.g., PharMed® BPT, Tygon® LFL, and Norprene® A-60-F), with tube bore diameters ranging from 0.1 mm to 3.2 mm depending on selected cassette configuration. All wetted components—including rollers, housing, and mounting hardware—are chemically inert and compatible with aqueous buffers, organic solvents (e.g., ethanol, acetonitrile), and mild acids/bases. The pump meets CE marking requirements under Directive 2014/30/EU (EMC) and 2014/35/EU (LVD), complies with RoHS 2011/65/EU restrictions on hazardous substances, and carries UL Recognition under File E327921 for use in Class I, Division 2 hazardous locations. It supports audit-ready operation when used with FDA 21 CFR Part 11–compliant software extensions.

Software & Data Management

While fully functional as a stand-alone instrument, the ISM931C supports bidirectional communication via ASCII-based RS-232 protocol. When connected to host PCs running Ismatec’s PumpWare™ PC software (v3.2+), users gain access to advanced features including method storage (up to 100 protocols), real-time flow logging at 100 ms intervals, event-triggered data export (CSV/TXT), and electronic signature-enabled parameter locking. Audit trails record all operator actions—including mode changes, speed adjustments, and start/stop events—with timestamps and user IDs. Data files retain metadata compliant with ISO/IEC 17025 clause 7.5.2 for measurement traceability.

Applications

• Automated sample dilution and standard addition in ICP-MS and AAS preparation workflows.
• Controlled nutrient feeding in single-use bioreactors and microbioreactor arrays.
• Continuous eluent delivery in ion chromatography and gradient HPLC systems requiring pulse-dampened flow.
• Calibration standard delivery in environmental testing labs performing EPA Method 200.7 or ISO 11885 analysis.
• Low-shear transfer of shear-sensitive biological suspensions—including primary neurons and organoid cultures—without compromising viability.

FAQ

What tubing sizes are supported by the ISM931C?

The pump operates with dual-channel cassettes accommodating inner diameters from 0.1 mm to 3.2 mm, including common sizes such as 0.5 mm, 1.6 mm, and 2.4 mm—each requiring corresponding Click’n’go™ cassette part numbers.
Does the ISM931C support regulatory compliance for pharmaceutical QC?

Yes—when paired with PumpWare™ and configured with electronic signatures, audit trail logging, and parameter lockdown, it fulfills key elements of USP , ASTM E2500, and Annex 11 requirements for automated liquid handling equipment.
Can the pump operate continuously for extended periods?

Designed for unattended 24/7 operation, the planetary gearmotor and sealed roller bearings ensure thermal stability and minimal wear; typical mean time between failures exceeds 20,000 hours under nominal load conditions.
Is remote start/stop capability available without a computer?

Yes—using the optional analog input module (part no. 78001-50), users can trigger run/pause functions via TTL-level signals or 0–10 VDC control lines, enabling seamless integration with PLC-based lab automation.
How is calibration verified and maintained?

Accuracy is factory-verified using gravimetric methods traceable to NIST standards; users may perform routine verification using certified volumetric flasks and analytical balances per ISO 8655-3, with deviation reporting integrated into PumpWare™ logs.