Junyi JY300HC Electrophoresis Power Supply

Overview

The Junyi JY300HC Electrophoresis Power Supply is a microprocessor-controlled, multi-mode DC power source engineered for precision and reliability in routine and advanced electrophoretic separations. Designed specifically for life science laboratories performing SDS-PAGE, native PAGE, isoelectric focusing (IEF), Western blot transfer (both wet and semi-dry), agarose gel electrophoresis, and acetate membrane electrophoresis, the JY300HC delivers stable, programmable output across three independent operating modes: constant voltage (CV), constant current (CC), and constant power (CP). Its architecture adheres to fundamental electrophoretic physics—ensuring Ohmic heating control, reproducible migration kinetics, and minimal band distortion under variable gel resistance conditions. The unit operates within a regulated 10–300 V range, supporting standard vertical mini-gel systems (e.g., Bio-Rad Mini-PROTEAN®), horizontal slab gels, and capillary-based transfer setups. Its compact footprint (280 × 237 × 118 mm) and lightweight chassis (3.2 kg) enable seamless integration into crowded benchtop environments without compromising thermal stability or electrical isolation.

Key Features

• Triple-output mode control (CV/CC/CP) with real-time switching and on-screen mode confirmation
• High-resolution digital display (128×64 pixel backlit LCD) showing both setpoint and actual output values simultaneously
• 10-user-programmable method storage with automatic recall and parameter validation
• Intelligent safety architecture including overload cutoff, no-load detection, and earth-leakage monitoring per IEC 61010-1 Class II insulation standards
• Tactile membrane keypad with ergonomic layout and haptic feedback for glove-compatible operation
• Integrated timer with 1-minute to 99-hour 59-minute resolution, supporting both countdown and continuous run modes
• Four isolated dual-terminal output ports (total 8 terminals), enabling parallel operation of multiple electrophoresis units or simultaneous transfer and separation protocols
• One-piece molded housing with reinforced ABS polymer construction, optimized for ESD dissipation and mechanical durability in shared lab spaces

Sample Compatibility & Compliance

The JY300HC is validated for use with commercially available electrophoresis tanks and transfer modules from major OEMs—including Thermo Fisher (Novex™), Bio-Rad (Mini-PROTEAN®, Trans-Blot®), and C.B.S. Scientific—without adapter modification. It supports all common gel matrices: polyacrylamide (8–20% T), agarose (0.5–3.0%), cellulose acetate, and nitrocellulose/PVDF membranes. While not certified to GLP or GMP regulatory frameworks as a standalone device, its programmable memory, audit-ready timer logs, and deterministic output behavior align with internal SOP documentation requirements under ISO/IEC 17025 Clause 5.9 (method validation) and FDA 21 CFR Part 11 Annex A (electronic record integrity for non-critical instruments). All electrical safety design follows EN 61010-1:2010 + A1:2019 harmonized standards.

Software & Data Management

The JY300HC operates as a standalone instrument with embedded firmware—no external PC interface or proprietary software required. All operational parameters are stored in non-volatile EEPROM with battery-backed retention, ensuring method persistence across power cycles. The unit supports manual logging via timestamped LCD readouts, and when integrated into automated workflows, its stable analog output enables synchronization with external data acquisition systems (e.g., LabVIEW™ or MATLAB® via optional analog voltage/current monitoring outputs). For laboratories requiring electronic record retention, the built-in timer log (with start/stop timestamps and accumulated runtime) satisfies basic traceability needs per ALCOA+ principles for non-GxP electrophoresis applications.

Applications

• Denatured and native protein separation in vertical mini-gel systems (e.g., SDS-PAGE analysis of recombinant expression lysates)
• Horizontal agarose gel electrophoresis for DNA fragment sizing (up to 20 kb), plasmid topology assessment, and PCR product verification
• Electroblotting of proteins from polyacrylamide gels onto nitrocellulose or PVDF membranes for immunochemical detection
• Acetate membrane electrophoresis for clinical serum protein profiling (albumin, α1-, α2-, β-, γ-globulins)
• Two-dimensional electrophoresis first-dimension IEF runs requiring precise voltage ramping and stabilization
• Preparative electrophoresis and electroelution protocols where constant-power delivery minimizes thermal gradient formation

FAQ

Does the JY300HC support programmable voltage ramping for IEF applications?

Yes—the unit allows stepwise voltage adjustment via timed method segments, enabling controlled ramping from low initial voltage (e.g., 100 V) to final focusing voltage (e.g., 1000 V equivalent in series configurations), though maximum output remains capped at 300 V per channel.
Can it be used with high-resistance gels such as low-percentage agarose or thick polyacrylamide slabs?

Yes—its constant current and constant power modes automatically compensate for rising resistance during prolonged runs, maintaining consistent migration velocity and reducing band smearing.
Is the power-fail resume function enabled by default?

No—it is an optional hardware module (JY-PRM) that must be installed separately; when active, it restores pre-interruption voltage/current settings and resumes timing upon AC recovery.
What safety certifications does the JY300HC carry?

It conforms to CE marking requirements under the Low Voltage Directive (2014/35/EU) and EMC Directive (2014/30/EU); full test reports are available upon request for institutional procurement compliance review.
How many output channels can operate independently at once?

All four output port pairs share the same power supply rail and cannot operate at different voltages simultaneously; however, they may drive separate electrophoresis tanks in parallel under identical CV/CC/CP settings.