Labonce Labonce-250MI Mold Incubator

Overview

The Labonce Labonce-250MI Mold Incubator is a precision-engineered environmental chamber designed specifically for controlled fungal cultivation, BOD incubation, and microbiological assay protocols in regulated life science laboratories. It operates on a forced-air convection principle with an optimized airflow distribution system to ensure thermodynamic stability and spatial uniformity—critical parameters for reproducible mold growth kinetics, spore germination studies, and standardized pharmacopoeial testing (e.g., USP , EP 2.6.12). Unlike general-purpose incubators, the Labonce-250MI integrates refrigeration capability down to 0°C, enabling low-temperature mycological isolation and psychrotolerant strain maintenance without external cold-room dependency. Its all-SUS304 interior eliminates organic residue retention and supports routine sterilization cycles, meeting GLP-compliant facility requirements for contamination control.

Key Features

• Advanced air circulation architecture with multi-directional ducting ensures temperature uniformity ≤2.0°C at 37°C across the full 250 L working volume—validated per ISO 15189 Annex A.3.2 for clinical microbiology applications.
• High-integrity thermal envelope: exterior powder-coated carbon steel frame paired with seamless mirror-finish 304 stainless steel interior—resistant to ethanol, hydrogen peroxide vapor, and UV-C exposure.
• Industrial-grade hermetic compressor system delivers stable sub-ambient operation (0–60°C range) with noise emission <52 dB(A) at 1 m—suitable for open-plan QC labs.
• LCD-based microprocessor controller with programmable fan-speed modulation enables dynamic response to door-opening events and load-induced thermal inertia.
• Dual-stage safety architecture: primary PID-controlled heating/cooling loop plus independent mechanical over-temperature cutoff (adjustable 0–70°C) and compressor fault monitoring with latching alarm.
• Integrated infrastructure: 1× Φ50 mm pass-through port, four-position leveling casters with brakes, UV-C germicidal lamp (254 nm), and white LED interior illumination—all factory-installed and CE-marked.

Sample Compatibility & Compliance

The Labonce-250MI accommodates standard microbiological formats including Petri dishes (up to 150 mm), slant tubes, broth culture flasks (up to 2 L), and multi-well plates stacked on adjustable 304 stainless steel shelves (3 standard, up to 8 optional). Its validated temperature profile satisfies ASTM E2875-22 (Standard Practice for Performance Verification of Environmental Chambers) and aligns with WHO Technical Report Series No. 961 Annex 5 requirements for microbial growth equipment qualification. The unit complies with IEC 61010-1:2010 for laboratory electrical safety and carries China Compulsory Certification (CCC) for domestic deployment. When equipped with the optional MIT touchscreen controller, it implements role-based access control (RBAC), electronic signatures, and immutable audit trails compliant with FDA 21 CFR Part 11 Subpart B for regulated pharmaceutical and biotech environments.

Software & Data Management

Data integrity is maintained through dual-path logging: real-time internal flash memory records temperature every 30 seconds (retention ≥30 days), while the optional thermal dot-matrix printer provides hard-copy traceability for batch release documentation. All logged datasets export via USB 2.0 interface in CSV format—compatible with LIMS integration (e.g., Thermo Fisher SampleManager, LabVantage). The MIT upgrade adds Ethernet connectivity, remote monitoring via HTTPS-enabled web interface, and automated report generation (PDF/Excel) with configurable metadata fields (operator ID, sample ID, protocol version). Audit logs capture timestamped events including parameter changes, door openings, alarm triggers, and user logins—structured to support internal audits and regulatory inspections.

Applications

• Pharmaceutical quality control: fungal enumeration per USP , sterility test incubation (ISO 11737-1), and environmental monitoring media incubation.
• Environmental testing: BOD₅ determination (APHA 5210B), waterborne mold quantification (EPA Method 1603), and sediment toxicity assays.
• Food & beverage safety: yeast/mold plate count (AOAC 997.02), mycotoxin-producing strain propagation, and challenge testing under defined humidity gradients (when upgraded to MIS configuration).
• Agricultural research: phytopathogen culture maintenance (e.g., Fusarium, Aspergillus spp.), spore viability assessment, and antifungal efficacy screening.
• Academic microbiology: teaching labs requiring ISO/IEC 17025-aligned instrumentation for undergraduate and graduate-level mycology coursework.

FAQ

What is the minimum operating temperature of the Labonce-250MI?
The unit achieves stable operation from 0°C to 60°C, enabled by its imported hermetic compressor and optimized evaporator coil geometry.
Can the Labonce-250MI be used for humidity-controlled incubation?
No—the Labonce-250MI is a temperature-only incubator. For combined temperature/humidity control, specify the Labonce-250MIS variant (15–50°C, 50–85% RH).
Is the internal data logger compliant with 21 CFR Part 11?
The base model’s USB-exported CSV files meet ALCOA+ principles but lack electronic signature capability. Full Part 11 compliance requires the MIT touchscreen controller upgrade.
How many shelves are included, and what is their weight capacity?
Three 304 stainless steel shelves are supplied as standard, each rated for 15 kg distributed load. Additional shelves (max 8 total) are available as accessories.
Does the unit support external communication protocols such as Modbus or RS-485?
The standard LCD controller does not include serial communication ports. The MIT touchscreen option provides Modbus TCP/IP and optional RS-485 gateway modules for SCADA integration.