Labonce Labonce-250MIS Mold Incubator with Humidity Control

Overview

The Labonce Labonce-250MIS Mold Incubator with Humidity Control is a precision-engineered environmental chamber specifically designed for standardized fungal cultivation, BOD incubation, and regulated microbial growth studies in life science laboratories. Unlike general-purpose incubators, the Labonce-250MIS integrates tightly coupled temperature and relative humidity control—critical parameters for reproducible mycological assays, pharmaceutical stability testing per ICH Q1 guidelines, and water quality analysis (e.g., ISO 8192:2007 for wastewater BOD₅). Its operational range of 15–50 °C and programmable RH control between 50–85 %RH enable compliance with method-specific requirements for Aspergillus, Penicillium, and Candida species propagation, as well as filamentous mold isolation protocols used in food safety (ISO 21527-1) and clinical mycology (CLSI M51-A).

Key Features

• Advanced air circulation system with optimized duct geometry ensures temperature uniformity ≤2.0 °C at 37 °C and ≤3.0 °C across full operating range—validated per ASTM E2874-22 for incubator performance verification.
• Double-wall construction: exterior powder-coated steel for mechanical durability; interior chamber fabricated from electropolished 304 stainless steel—non-porous, corrosion-resistant, and compliant with USP surface cleanliness standards.
• High-efficiency hermetic refrigeration system using imported industrial-grade compressors, delivering stable low-temperature operation down to 15 °C with acoustic noise 30,000 hours.
• Intuitive LCD controller with adjustable fan speed settings, enabling fine-tuned airflow modulation to minimize moisture stratification during extended humidified runs.
• Dual-layer security architecture: independent over-temperature cut-off (mechanical backup), compressor high-pressure/overheat protection, and audible local alarm with visual status indicator.
• Integrated 100-mm diameter test port (with silicone plug), castor-mounted base for lab reconfiguration, LED interior lighting, and germicidal UV-C lamp (254 nm) for pre-cycle chamber decontamination.

Sample Compatibility & Compliance

The Labonce-250MIS accommodates standard microbiological formats including Petri dishes (up to 150 mm), multi-well plates, slant tubes, and liquid culture flasks on three adjustable stainless-steel shelves (expandable to eight). Its sealed chamber design prevents cross-contamination between samples while maintaining RH integrity under continuous operation. The unit meets structural and functional prerequisites for ISO/IEC 17025-accredited laboratories performing environmental monitoring (EM) in cleanrooms, as well as FDA-regulated facilities conducting sterility testing (USP ) and antimicrobial efficacy studies (ASTM E1053). Optional MIT touchscreen controller (not included) adds 21 CFR Part 11-compliant audit trail, electronic signatures, and role-based access control (three-tier permission hierarchy).

Software & Data Management

Equipped with embedded non-volatile memory capable of logging temperature and humidity values at user-defined intervals (1–60 min), the Labonce-250MIS supports traceable data acquisition for GLP/GMP documentation. Logged datasets are exportable via USB flash drive in CSV format—compatible with LIMS integration and statistical process control (SPC) software. The optional thermal line printer provides real-time hard-copy output of setpoints, measured values, and alarm events—satisfying ALCOA+ data integrity principles (Attributable, Legible, Contemporaneous, Original, Accurate). All firmware adheres to IEC 62304 Class B medical device software safety standards.

Applications

• Regulatory-compliant mold enumeration in drinking water (ISO 16266), indoor air (ISO 16000-17), and pharmaceutical manufacturing environments.
• Biochemical Oxygen Demand (BOD₅) incubation per APHA 5210B and EPA 405.1 protocols.
• Fungal preservation and subculturing in university and public health microbiology labs.
• Stability studies for biologics and excipients under accelerated humidity conditions (ICH Q1A–Q1E).
• Validation of disinfectant efficacy against spore-forming organisms (e.g., Bacillus atrophaeus) per AOAC 955.15.

FAQ

What is the maximum permissible ambient temperature for reliable operation?
The unit is rated for continuous use in ambient conditions between +5 °C and +35 °C. Operation above 35 °C may compromise compressor efficiency and humidity control accuracy.
Does the Labonce-250MIS support remote monitoring or Ethernet connectivity?
Standard configuration includes local USB data export only. Remote supervision requires integration via optional MIT controller with RS485/Modbus RTU or Ethernet TCP/IP interface.
Can the UV lamp be operated simultaneously with temperature/humidity control?
No—the UV-C lamp is interlocked with the main chamber door and automatically de-energizes when opened. It is intended for sterilization cycles only, not concurrent with active incubation.
Is calibration certificate included with shipment?
A factory-issued calibration report (traceable to NIM, China) is provided. Full ISO/IEC 17025 calibration with uncertainty budget is available as a service option.
What maintenance intervals are recommended for long-term reliability?
Compressor oil and refrigerant levels should be verified annually; condenser coil cleaning every six months; UV lamp replacement every 1,000 hours of cumulative use.