Labthink C850H Integrated Water-Insoluble Matter Detection System
| Brand | Labthink |
|---|---|
| Model | C850H |
| Origin | Shandong, China |
| Manufacturer Type | Direct Manufacturer |
| Regional Classification | Domestic (China) |
| Pricing | Upon Request |
Overview
The Labthink C850H Integrated Water-Insoluble Matter Detection System is a dedicated analytical instrument engineered for the quantitative determination of water-insoluble particulate matter in liquid-phase chemical products, process waters, and aqueous formulations used across packaging-related manufacturing and quality control environments. It operates on the principle of gravimetric filtration analysis: a defined volume of sample is vacuum-filtered through a pre-weighed, standardized microporous membrane (typically 0.45 µm or 0.8 µm pore size), followed by controlled drying and post-filtration weighing to determine the mass of retained insoluble residue. This methodology aligns with widely accepted industrial test protocols—including ASTM D2989 (Standard Test Method for Insoluble Residue in Aqueous Solutions), ISO 11926 (Water quality — Determination of suspended solids), and relevant sections of USP & EP general chapters on particulate matter—providing traceable, reproducible results essential for compliance-driven production workflows.
Key Features
- Integrated workflow architecture: Combines precision vacuum filtration, temperature-controlled drying chamber, and high-resolution analytical balance (0.01 mg readability) within a single compact footprint—eliminating inter-device transfer errors and reducing operator handling variability.
- Dual-membrane support: Accommodates standard 47 mm diameter membranes (cellulose acetate, mixed ester, or polyethersulfone) with interchangeable filter holders for method flexibility and cross-laboratory comparability.
- Programmable filtration parameters: Adjustable vacuum pressure (10–80 kPa range), real-time flow monitoring, and automatic endpoint detection based on filtrate cessation—ensuring consistent filtration kinetics across diverse sample viscosities and particulate loadings.
- ISO 17025-aligned calibration traceability: Balance and vacuum sensor are factory-calibrated against NIST-traceable standards; system-level verification procedures support internal audit readiness.
- Ergonomic design with HEPA-filtered exhaust: Minimizes operator exposure to airborne particulates during membrane handling and drying; compliant with OSHA and EU Directive 2004/37/EC (carcinogens and mutagens) best practices for lab safety.
Sample Compatibility & Compliance
The C850H is validated for use with aqueous solutions, emulsions, polymer dispersions, cleaning agents, ink diluents, adhesive precursors, and rinse waters commonly encountered in flexible packaging, pharmaceutical primary packaging, and food-contact material manufacturing. It supports both routine QC testing and root-cause investigation of particulate contamination events. All operational procedures adhere to GLP documentation requirements, including electronic audit trails for weight records, filtration timestamps, and user authentication logs—fully compatible with FDA 21 CFR Part 11-compliant data management systems when interfaced via RS-232 or USB.
Software & Data Management
Controlled via Labthink’s proprietary WinTest v4.2 software (Windows 10/11 compatible), the C850H enables automated report generation in PDF and CSV formats, with embedded metadata (operator ID, sample ID, batch number, environmental conditions). The software enforces SOP-driven test sequences, prevents unauthorized parameter modification via role-based access control (RBAC), and maintains full revision history of method files. Raw balance data and time-stamped filtration curves are stored locally with optional cloud backup—supporting long-term trend analysis per ISO 9001 Clause 8.5.2 (Control of nonconforming output) and ICH Q5C stability protocol alignment.
Applications
- Verification of filtration efficiency in solvent recovery loops for flexographic and gravure ink systems.
- Release testing of aqueous-based barrier coatings prior to laminating operations.
- Monitoring of particulate carryover in ultrapure water circuits supplying cleanroom packaging assembly lines.
- Stability assessment of water-dispersible hot-melt adhesives under accelerated aging conditions.
- Compliance validation against customer-specific technical specifications (e.g., ≤0.5 mg/L insolubles for pharmaceutical blister packaging rinse water).
FAQ
What membrane pore sizes are supported by the C850H?
The system is optimized for 0.45 µm and 0.8 µm nominal pore size membranes; custom holders can be configured for 25 mm or 50 mm formats upon request.
Can the C850H be integrated into an existing LIMS environment?
Yes—via configurable ASCII-based data export or OPC UA interface modules (optional add-on), enabling bidirectional communication with major LIMS platforms including Thermo Fisher SampleManager and LabVantage.
Is method validation support provided with the instrument?
Labthink delivers IQ/OQ documentation packages and assists with PQ protocol development aligned with ISO/IEC 17025:2017 Annex A.3 and USP guidance.
What maintenance intervals are recommended for routine operation?
Vacuum pump oil replacement every 6 months; balance recalibration quarterly; membrane holder cleaning after each batch using IPA-rinsed lint-free wipes—full PM schedule included in the user manual.
