Masterflex B/T Variable-Speed Peristaltic Pump Model 77111-77

Overview

The Masterflex B/T Variable-Speed Peristaltic Pump Model 77111-77 is an industrial-grade peristaltic pump engineered for continuous, high-flow fluid transfer in demanding laboratory and pilot-scale process environments. Utilizing the fundamental principle of peristalsis—where rollers compress a flexible tubing segment against a rigid housing to generate positive displacement—the B/T series delivers pulse-free, contamination-free flow without valves, seals, or internal wetted parts. This design ensures complete fluid isolation, making it ideal for handling shear-sensitive, abrasive, viscous, or sterile media where cross-contamination or chemical compatibility must be rigorously controlled. The 77111-77 variant features a robust brushless DC motor with analog and digital speed control interfaces, enabling precise adjustment across its full operational range of 11–321 rpm. With a maximum flow capacity of 42 L/min (11.1 GPM) using standard silicone or PharMed® BPT tubing, this pump supports scalable applications from analytical sample delivery to bulk reagent dosing in bioprocessing and environmental monitoring workflows.

Key Features

• Brushless DC motor with extended service life and consistent torque output across the entire speed range (11–321 rpm)
• Dual-mode speed control: front-panel rotary potentiometer + 0–10 VDC analog input for integration into PLC or SCADA systems
• High-torque drive mechanism optimized for large-diameter tubing (up to 19 mm I.D.) and elevated backpressure conditions
• IP54-rated enclosure with corrosion-resistant aluminum housing and stainless-steel hardware for durability in humid or chemically exposed lab environments
• Integrated thermal protection and stall detection to prevent motor overload during tubing occlusion or dry-run scenarios
• Compliance-ready design supporting traceable operation logs when paired with optional Masterflex Flow Control Software and USB/RS-485 interface modules

Sample Compatibility & Compliance

The Model 77111-77 accommodates a wide selection of FDA-compliant, USP Class VI-certified pump tubing—including silicone, Viton®, C-Flex®, and PharMed® BPT—enabling validated use with aqueous buffers, organic solvents, cell culture media, and mild acids/bases. Tubing selection directly governs chemical resistance, pressure tolerance, and particulate generation profile. For regulated environments, the pump’s repeatable speed calibration (±0.2% of setpoint), minimal flow drift (<0.5% over 8 hours), and compatibility with audit-trail-capable software align with GLP and GMP documentation requirements. While the pump itself is not certified to UL/CE as a standalone device, it meets IEC 61000-6-2 (immunity) and IEC 61000-6-4 (emission) standards when installed per manufacturer guidelines and used with approved tubing and power supplies.

Software & Data Management

When equipped with the optional Masterflex Flow Control Software (v3.2+), the 77111-77 supports time-stamped flow logging, programmable ramp profiles, multi-pump synchronization, and export of CSV-formatted datasets for LIMS or ELN integration. The software complies with FDA 21 CFR Part 11 requirements when deployed with user access controls, electronic signatures, and system-generated audit trails. Real-time flow estimation is derived from calibrated tubing inner diameter, roller geometry, and rotational speed—no external flowmeter required for routine operation. Optional RS-485 Modbus RTU communication enables bidirectional parameter exchange in automated liquid handling platforms.

Applications

• Continuous feed of nutrient media or harvest streams in upstream bioreactor and downstream tangential flow filtration (TFF) systems
• Accurate metering of calibration standards and reference materials in environmental water quality labs (EPA Method 200.7, 300.0)
• Transfer of aggressive cleaning-in-place (CIP) solutions in pharmaceutical cleanroom utilities
• High-volume solvent delivery in preparative chromatography and extraction workflows
• Controlled dosing of flocculants or coagulants in wastewater treatment pilot studies
• Recirculation loops for temperature-controlled stability testing chambers

FAQ

What tubing sizes are compatible with the Model 77111-77?
Standard configurations support tubing inner diameters from 3.2 mm to 19.1 mm; recommended maximum wall thickness is 3.2 mm for optimal occlusion and longevity.
Can this pump operate under backpressure?
Yes—it maintains rated flow up to 345 kPa (50 psi) with appropriate tubing selection; performance degrades predictably beyond that threshold and must be verified empirically for each fluid/tubing combination.
Is speed calibration traceable to NIST standards?
Masterflex provides factory calibration certificates with uncertainty values; end users may perform in-house verification using a calibrated tachometer and volumetric collection method per ASTM D3743.
Does the pump support remote start/stop via digital I/O?
Yes—optional digital input module enables TTL-level run/stop, direction control, and fault signaling compatible with common industrial controllers.
How often should tubing be replaced during continuous operation?
Typical service life ranges from 100–500 hours depending on speed, pressure, fluid chemistry, and tubing material; scheduled replacement is strongly advised over failure-based maintenance to ensure flow accuracy and prevent downtime.