Metrohm 719 SET Basic Automatic Potentiometric Titrator
| Origin | Switzerland |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported Instrument |
| Model | 719 SET Basic |
| Pricing | Available Upon Request |
Overview
The Metrohm 719 SET Basic Automatic Potentiometric Titrator is a dedicated, entry-level potentiometric titration system engineered for reproducible endpoint detection in routine quality control and teaching laboratories. It operates on the fundamental principle of potentiometric titration—measuring the potential difference between a reference electrode and an indicator electrode as titrant is incrementally added—enabling precise determination of stoichiometric endpoints without reliance on visual indicators. Unlike dynamic or derivative-based titration modes (e.g., equivalence point detection via first or second derivative analysis), the 719 SET Basic is optimized exclusively for fixed-endpoint (SET) titrations, where the user defines a target potential threshold (in mV) or pH value at which titration terminates. This architecture ensures operational simplicity, reduced method development time, and high inter-operator consistency—particularly valuable in regulated environments where procedural standardization is critical.
Key Features
- Dedicated SET (Set-Endpoint) mode with configurable termination criteria: user-defined mV or pH threshold, with adjustable tolerance window (±1–5 mV or ±0.02–0.1 pH units)
- Integrated burette drive with glass syringe burette (10 mL or 20 mL capacity), delivering volumetric accuracy compliant with ISO 8655-3 (±0.1% at full scale)
- Automatic electrode recognition via digital ID chip (when used with Metrohm’s iTip or Pt-ring electrodes), ensuring correct calibration history association
- Onboard method storage for up to 20 pre-programmed titration protocols—including standardized methods for acid-base titration (ASTM D974, ISO 3682), chloride (Mohr method, ISO 9297), Kjeldahl nitrogen (ISO 5983), and ascorbic acid (AOAC 967.21)
- Robust electromechanical architecture with sealed stepper motor drive and anti-drip valve design to minimize reagent waste and cross-contamination
- Compliance-ready firmware supporting audit trail logging (user ID, timestamp, parameter changes, result export events) in alignment with GLP and FDA 21 CFR Part 11 data integrity requirements
Sample Compatibility & Compliance
The 719 SET Basic accommodates aqueous and mildly organic solvent systems (e.g., methanol/water mixtures up to 30% v/v) and supports standard double-junction reference electrodes (e.g., Ag/AgCl/KCl 3 mol/L) and ion-selective indicator electrodes (e.g., glass pH, silver, platinum). It meets mechanical and electrical safety standards per IEC 61010-1:2010 and electromagnetic compatibility per IEC 61326-1:2020. While not certified for fully automated GMP production environments, its firmware and documentation support IQ/OQ validation protocols required by pharmaceutical, food, and environmental testing labs operating under ISO/IEC 17025 accreditation frameworks.
Software & Data Management
The instrument operates standalone via its integrated LCD touchscreen interface (no PC dependency required), but also interfaces seamlessly with Metrohm’s tiamo™ software (v3.2 or later) via USB or RS-232. tiamo™ enables advanced data review, report generation (PDF/CSV), electronic signature workflows, and integration with LIMS via ASTM E1384-compliant data exchange. All raw titration curves, endpoint calculations, and metadata are stored with immutable timestamps and user authentication logs—ensuring full traceability for regulatory audits. Data encryption (AES-256) and role-based access control (administrator/operator) are enforced during networked operation.
Applications
- Quality assurance of raw materials and finished products in food & beverage (e.g., titratable acidity in dairy, free fatty acids in oils)
- Environmental water analysis (chloride in wastewater per EPA Method 325.2, alkalinity per APHA 2320B)
- Pharmaceutical excipient testing (acid value of stearic acid per USP <467>, residual carbonate in sodium bicarbonate)
- Academic teaching labs for foundational electrochemical principles and quantitative analysis coursework
- Veterinary diagnostics (vitamin C stability testing in feed supplements per AOAC 984.27)
FAQ
Does the 719 SET Basic support equivalence point detection algorithms (e.g., first derivative)?
No. The 719 SET Basic is purpose-built for fixed-endpoint titrations only. For derivative-based equivalence point detection, consider the Metrohm Titrando 856 or 905 Touch series.
Can it be upgraded to perform photometric or thermometric titrations?
No. Hardware architecture lacks optical sensors or temperature differential modules. Multi-mode functionality requires dedicated platforms such as the 856 Titrotherm or 851 Phototrode systems.
Is GLP-compliant data archiving supported out-of-the-box?
Yes—audit trail logging, electronic signatures (via tiamo™), and encrypted local storage meet core GLP requirements. Full 21 CFR Part 11 compliance requires tiamo™ configuration with validated IT infrastructure.
What electrode types are natively recognized?
All Metrohm iElectrodes with embedded digital identification chips (e.g., iPt, iAg, iPh) are auto-detected. Conventional analog electrodes require manual selection and calibration verification.
Is service and calibration support available globally?
Yes—Metrohm’s authorized distributor network provides local calibration services traceable to NIST or PTB standards, along with preventive maintenance contracts and spare parts logistics.
