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Mettler Toledo AL104 Advanced Analytical Balance

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Origin Shanghai, China
Manufacturer Type Authorized Distributor
Product Origin Domestic (China)
Model AL104
Readability 0.1 mg
Maximum Capacity 110 g
Repeatability (s) 0.1 mg
Linearity ±0.2 mg
Calibration External, 100 g weight (optional)
Pan Diameter Φ90 mm
Draft Shield Height 220 mm
Dimensions (W×D×H) 238 × 335 × 364 mm
Interface RS232
Compliance ISO/IEC 17025–compatible operation, GLP/GMP-ready audit trail support via e-Loader II software

Overview

The Mettler Toledo AL104 Advanced Analytical Balance is a high-precision laboratory instrument engineered for routine quantitative analysis in quality control, research, and educational environments. Based on electromagnetic force compensation (EMFC) technology, the AL104 delivers stable, drift-compensated measurements with 0.1 mg readability across its 110 g maximum capacity. Its monolithic sensor architecture and temperature-stabilized weighing cell ensure consistent performance under variable ambient conditions—critical for applications requiring traceable mass determination per ISO 9001, ISO/IEC 17025, and USP guidelines. Designed as part of the AL Classic series, the balance prioritizes operational robustness without compromising metrological integrity, making it suitable for ISO-classified laboratories where calibration traceability, repeatability, and documentation compliance are mandatory.

Key Features

  • Electromagnetic force compensation (EMFC) transducer with automatic internal temperature compensation for minimized thermal drift
  • Durable ABS engineering plastic housing—resistant to common lab solvents and mechanical impact, supporting long-term structural stability
  • Backlit LCD display with intuitive icon-based menu navigation and tactile keypad layout optimized for gloved-hand operation
  • External calibration capability using a certified 100 g weight (optional accessory), enabling user-performed verification aligned with ASTM E898 and EURAMET cg-18
  • RS232 serial interface compliant with standard printer and PC protocols; supports ASCII output formatting for direct integration into LIMS or ELN systems
  • In-use protective cover included as standard—chemically inert polymer shield minimizes contamination risk from powder spillage or corrosive residue
  • Preloaded application modes: basic weighing, percentage weighing, piece counting, dynamic weighing (for unstable samples), net/gross/tare arithmetic, and subtraction weighing

Sample Compatibility & Compliance

The AL104 accommodates a broad range of sample types—including powders, granules, liquids in tared vessels, and small solid components—within its 90 mm diameter stainless steel weighing pan and 220 mm draft shield height. Its enclosed design meets Class II environmental requirements per OIML R76-1 for analytical balances used in regulated settings. The balance supports GLP and GMP workflows through configurable user access levels, timestamped event logging, and full audit trail export via RS232. While not inherently 21 CFR Part 11–compliant, its data output structure and e-Loader II firmware update protocol enable integration with validated third-party software platforms that provide electronic signature and record retention functionality.

Software & Data Management

The AL104 operates with embedded firmware supporting real-time data streaming and local parameter configuration. It is compatible with Mettler Toledo’s e-Loader II software—a Windows-based utility enabling secure firmware updates, calibration certificate import, and customizable print template definition. Raw weighing data can be exported in CSV or TXT format for post-processing in Excel, MATLAB, or statistical analysis packages. When connected to a compliant host system, the balance satisfies data integrity requirements outlined in Annex 11 (EU GMP) and ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available).

Applications

This analytical balance is routinely deployed in pharmaceutical QC labs for active pharmaceutical ingredient (API) assay preparation, excipient blending verification, and dissolution tablet weight uniformity testing per USP . In academic chemistry laboratories, it supports stoichiometric reagent dispensing, gravimetric standard solution preparation, and catalyst loading quantification. Industrial applications include incoming raw material inspection, formulation batch release checks, and environmental sample ash content determination (ASTM D3174). Its repeatability specification (≤0.1 mg s.d.) ensures reliability in low-mass differential measurements—such as filter membrane weight gain in particulate matter analysis.

FAQ

Is the AL104 compliant with ISO/IEC 17025 calibration requirements?

Yes—the balance supports external calibration using traceable weights and records calibration events with timestamps and operator ID when integrated with compliant software.

Can the AL104 be connected to a networked LIMS?

Direct Ethernet or Wi-Fi connectivity is not supported; however, RS232-to-TCP/IP gateways enable seamless LIMS integration with appropriate middleware configuration.

What is the recommended recalibration frequency?

Per ISO 17025 Clause 6.5.2, recalibration interval should be determined by risk assessment—typically daily zero check, weekly span verification, and formal external calibration every 3–6 months depending on usage intensity and criticality.

Does the AL104 support density determination?

No—density measurement requires additional hardware (e.g., density kit with sinker and auxiliary display); this function is available on higher-tier models such as the ME or XSE series.

Is the protective cover autoclavable?

No—the included in-use cover is made of polycarbonate-acrylonitrile butadiene styrene (PC-ABS) blend and is intended for chemical splash protection only; it is not rated for steam sterilization.

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