METTLER TOLEDO LE403E Precision Analytical Balance
| Brand | METTLER TOLEDO |
|---|---|
| Origin | Beijing, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic (China-manufactured) |
| Model | LE403E |
| Instrument Type | Precision Balance |
| Maximum Capacity | 420 g |
| Readability | 1.0 mg |
| Repeatability | 1.0 mg |
| Calibration Method | External |
| Weighing Pan Diameter | 100.0 mm |
| Power Supply | AC Mains |
Overview
The METTLER TOLEDO LE403E Precision Analytical Balance is an entry-level analytical balance engineered for laboratories requiring reliable mass measurement at the 1.0 mg readability level. Designed and manufactured in Beijing under strict METTLER TOLEDO quality governance, the LE403E implements electromagnetic force compensation (EMFC) technology — the industry-standard principle for high-stability analytical weighing — to deliver consistent, drift-resistant results across variable ambient conditions. While positioned within the value-oriented segment of METTLER TOLEDO’s portfolio, the LE403E retains core design hallmarks including a robust monolithic weighing cell, draft shield-compatible architecture, and thermally stable internal mechanics. It serves as a calibrated reference instrument for routine QC checks, sample preparation, formulation tasks, and educational laboratory instruction where traceable, repeatable mass determination is required but ultra-micro sensitivity is not mandated.
Key Features
- Electromagnetic force compensation (EMFC) transduction system ensuring long-term stability and minimal thermal drift
- 1.0 mg readability with 420 g maximum capacity — optimized for applications demanding sub-gram resolution without microgram-level instrumentation
- 100.0 mm diameter stainless steel weighing pan compatible with standard lab glassware and sample containers
- External calibration capability using certified weights (e.g., Class M2 or better), supporting user-initiated verification and periodic recalibration per ISO/IEC 17025 requirements
- AC mains-powered operation with integrated overload protection and automatic zero-tracking function
- Compact footprint (210 × 320 × 320 mm) and lightweight construction (approx. 4.2 kg), suitable for benchtop deployment in constrained laboratory spaces
- IP42-rated housing providing resistance against dust ingress and incidental liquid splashes during routine handling
Sample Compatibility & Compliance
The LE403E accommodates solid samples, powders, granules, and small-volume liquids placed directly on the pan or within tared containers. Its open-frame design allows straightforward integration with desiccators, static-dissipative trays, and non-magnetic accessories. The balance complies with international metrological standards including OIML R 76-1 (2006) for non-automatic weighing instruments and meets essential requirements of the EU Measuring Instruments Directive (MID) Annex MI-001 when configured with appropriate verification markings. While not pre-certified for GMP or GLP environments out-of-the-box, its external calibration pathway, audit-ready calibration logs (when paired with optional software), and stable performance support alignment with FDA 21 CFR Part 11 data integrity expectations when deployed with documented SOPs.
Software & Data Management
The LE403E features an RS232 interface for direct connection to PCs or printers. When used with METTLER TOLEDO’s free LabX Lite software (or third-party SCADA/HMI systems supporting ASCII protocol), users can capture weight values with timestamps, generate CSV reports, and implement basic data archiving workflows. All communication adheres to standard METTLER TOLEDO ASCII command syntax, enabling compatibility with LIMS integrations via serial-to-ethernet gateways. No onboard memory or internal database is present; data persistence relies entirely on external host systems — a design choice that simplifies validation and reduces regulatory burden in regulated environments.
Applications
- Quality control testing in pharmaceutical excipient and intermediate manufacturing (e.g., batch sampling, content uniformity checks)
- Weighing reagents and standards in environmental testing labs (e.g., EPA Method 525.3, ASTM D7279)
- Formulation support in food and beverage R&D, including dry blend proportioning and additive dosing
- Teaching laboratories for fundamental metrology concepts, uncertainty propagation exercises, and calibration methodology instruction
- In-process verification in electronics assembly (e.g., solder paste volume estimation via mass-to-volume correlation)
- Inventory management of reference materials and certified standards in calibration labs
FAQ
Is the LE403E manufactured in Switzerland?
No — the LE403E is produced at METTLER TOLEDO’s ISO 13485-certified facility in Beijing, China, under full technical supervision and quality oversight from the global headquarters in Greifensee, Switzerland.
Does this balance support internal calibration?
No — the LE403E requires external calibration using traceable weights; it does not include motorized internal calibration mechanisms.
What is the recommended calibration frequency?
Calibration interval must be determined by risk assessment per ISO/IEC 17025:2017 Clause 5.10.3; typical practice ranges from daily zero checks to weekly full-range verification depending on usage intensity and criticality of measurements.
Can the LE403E be connected to a networked LIMS?
Yes — via RS232-to-Ethernet converter and ASCII-based middleware, enabling automated data transfer into validated LIMS platforms when supported by site-specific IT infrastructure and change control documentation.
Is the weighing pan removable for cleaning?
Yes — the stainless steel pan is mechanically detachable without tools, facilitating thorough decontamination in compliance with lab hygiene protocols.

