Raykol BP-100 Automated High-Throughput Liquid Dispenser

Overview

The Raykol BP-100 Automated High-Throughput Liquid Dispenser is an engineered solution for precise, repeatable, and scalable liquid dispensing in microbiological testing laboratories. Designed around a three-axis robotic arm architecture coupled with high-torque, calibrated peristaltic pump modules, the system delivers volumetric accuracy across a broad dynamic range—from microliter-scale reagent aliquoting to liter-volume buffer distribution. Its core operational principle relies on positive displacement via elastomeric tubing, ensuring compatibility with viscous, foaming, or particulate-containing solutions without cross-contamination risk. The BP-100 is purpose-built for standardized microbial enumeration workflows where reproducibility, traceability, and regulatory compliance are non-negotiable—particularly in GLP- and GMP-aligned environments conducting routine sample preparation for colony-forming unit (CFU) assays, enrichment media dispensing, and dilution series generation.

Key Features

• Integrated 7-inch color touchscreen HMI: Standalone operation without external PC; intuitive graphical interface supporting protocol creation, editing, and execution
• Dual-zone dispensing architecture (A/B zones): Enables simultaneous handling of two distinct container types (e.g., 18 mm × 180 mm test tubes and 50 mL conical tubes) with independent volume programming per zone
• High-throughput capacity: Supports up to 320 positions on standard racks; plate layout and carrier configuration are fully customizable for OEM integration or lab-specific workflows
• Modular fluid path design: All wetted components—including tubing, nozzles, and fluid manifolds—are removable and autoclavable at 121°C for 20 minutes, meeting ISO 13485 and USP sterility assurance requirements
• Multi-mode calibration suite: Includes automated gravimetric calibration, manual offset adjustment, and user-defined calibration curves—each logged with timestamp, operator ID, and environmental conditions for audit readiness
• Robust mechanical construction: Aluminum alloy frame with IP20-rated enclosure; optimized footprint (42 × 32 × 46 cm) for benchtop deployment in biosafety cabinets or cleanroom-adjacent workspaces

Sample Compatibility & Compliance

The BP-100 accommodates a wide spectrum of laboratory vessels—including screw-cap tubes, snap-cap centrifuge tubes, glass and plastic flasks, Petri dish stacks, and multi-well plates—via adjustable rack adapters. Its peristaltic pumping mechanism eliminates dead volume concerns and prevents carryover between dispense cycles, critical for low-bioburden applications. The instrument complies with key regulatory frameworks governing microbiological testing: it supports data integrity requirements under FDA 21 CFR Part 11 (with optional electronic signature module), aligns with ISO/IEC 17025 documentation standards for method validation, and facilitates adherence to pharmacopeial monographs including USP , , and . Validation packages include IQ/OQ documentation templates compatible with EU Annex 11 and WHO TRS 992 Annex 6.

Software & Data Management

The embedded firmware provides full audit trail functionality: every dispense event records volume delivered, target position, timestamp, calibration status, and operator credentials. Exportable logs are generated in CSV and PDF formats compliant with ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available). Optional Ethernet/Wi-Fi connectivity enables remote monitoring and integration into LIMS via HL7 or RESTful API interfaces. Software updates are performed via secure USB authentication to maintain system integrity throughout its lifecycle.

Applications

The BP-100 is routinely deployed in quality control laboratories performing standardized microbial assays per national and international guidelines. These include—but are not limited to—GB 4789 series (China National Food Safety Standards), GB/T 5750.12 (drinking water microbiology), GB/T 7918 (cosmetic microbiology), Chinese Pharmacopoeia 2020 Edition General Chapters 1105 and 1106 (microbial limits testing), and GB/T 13091 (feed microbiology). It is equally suited for environmental monitoring (e.g., wastewater effluent testing), pharmaceutical raw material release, and contract research organization (CRO) service labs requiring high-volume sample prep under ISO 17025 accreditation.

FAQ

What types of liquids can the BP-100 dispense?
It handles aqueous buffers, saline solutions, liquid culture media (e.g., TSB, PCA), enzymatic reagents, and low-viscosity disinfectants—provided they do not degrade silicone or Santoprene tubing.
Is the system validated for use in regulated environments?
Yes; IQ/OQ documentation templates are provided, and the system supports 21 CFR Part 11-compliant electronic records when paired with optional access control and digital signature modules.
Can the BP-100 be integrated into existing automation workflows?
It features RS-232 and Ethernet ports for bidirectional communication with LIS/LIMS systems and can be synchronized with robotic arms or incubator loading stations via discrete I/O signals.
How often does calibration need to be performed?
Initial calibration is required post-installation and after any fluid path replacement; routine verification is recommended before each shift or per SOP-defined intervals based on usage intensity and regulatory scope.
Does the system support custom rack configurations beyond 320 positions?
Yes; Raykol offers engineering consultation for bespoke carrier designs, including carousel-based expansion modules and multi-tier stacking solutions for ultra-high-throughput labs.