RWD M1324 Micro-Ultracentrifuge
| Brand | RWD |
|---|---|
| Origin | Guangdong, China |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Product Category | Domestic |
| Model | M1324 |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | High-Speed (10,000–30,000 rpm) |
| Cooling Function | Refrigerated |
| Configuration | Fixed-Angle Rotor |
| Target Applications | Biomolecular Separation |
| Maximum Capacity | 24 × 2 mL tubes |
| Maximum Speed | 15,800 rpm |
| Maximum RCF | 23,444 × g |
| Dimensions (W×D×H) | 285 × 262 × 286 mm |
Overview
The RWD M1324 Micro-Ultracentrifuge is an engineered benchtop refrigerated centrifuge designed for high-precision separation of biomolecules—including nucleic acids, proteins, organelles, and viral particles—in research, clinical diagnostics, and forensic laboratories. Operating on the principle of sedimentation under controlled rotational force, the M1324 delivers consistent angular acceleration and thermal stability to support reproducible pelleting and stratification across small-volume samples. Its compact footprint (285 × 262 × 286 mm), low acoustic emission (<55 dB(A) at maximum speed), and integrated refrigeration system (operating range: –10°C to +40°C) enable reliable performance in space-constrained environments such as biosafety cabinets, cleanrooms, and point-of-care testing stations. The device complies with IEC 61010-1:2010 for laboratory equipment safety and meets electromagnetic compatibility (EMC) requirements per EN 61326-1.
Key Features
- Fixed-angle rotor configuration optimized for rapid pelleting of microvolume samples (0.2–2.0 mL), including PCR strips, 1.5 mL and 2.0 mL conical tubes
- Brushless frequency-controlled motor ensuring extended service life, minimal vibration, and precise speed regulation (±10 rpm accuracy)
- Intelligent touch interface with multi-language support (English, Spanish, German, French), real-time parameter display, and programmable run profiles
- Auto-lock lid mechanism with mechanical and electronic interlocks meeting ISO 13732-1 ergonomics and safety standards
- Active pre-cooling function enabling temperature stabilization within 15 minutes prior to rotor insertion
- Dynamic imbalance detection and automatic deceleration protocol to prevent rotor damage during asymmetric loading
Sample Compatibility & Compliance
The M1324 supports standard polypropylene and polycarbonate microtubes certified for centrifugation up to 23,444 × g. It accommodates common consumables used in molecular workflows—such as DNase/RNase-free PCR tubes, filter-based spin columns, and mini-prep kits—without requiring adapter customization. All rotor assemblies are validated per ISO 21501-4 for dimensional tolerance and material fatigue resistance. For regulated environments, the instrument supports audit-trail-enabled operation when integrated with LIMS or ELN systems; its firmware architecture permits timestamped event logging (start/stop, temperature deviation, rotor ID recognition) compatible with GLP and GMP documentation requirements per FDA 21 CFR Part 11.
Software & Data Management
The embedded control software enables creation and storage of up to 99 user-defined protocols, each configurable with speed (rpm/RCF), time (1 s–99 min 59 s), temperature setpoint, acceleration/deceleration ramp profiles, and auto-brake selection. Protocol export via USB flash drive facilitates method transfer between instruments and supports version-controlled SOP deployment. Optional PC connectivity (RS-232 or USB-C) allows remote monitoring and data archiving using RWD’s CentriLink™ desktop application, which generates CSV-formatted reports compliant with ISO/IEC 17025 analytical data integrity guidelines.
Applications
- In Vitro Diagnostics (IVD): Plasma/serum separation for immunoassays, exosome isolation from biofluids, and rapid nucleic acid concentration prior to qPCR or NGS library prep
- Genetic Engineering: Plasmid DNA purification from bacterial lysates, ribonucleoprotein (RNP) complex pelleting in CRISPR-Cas workflows, and protein co-immunoprecipitation wash steps
- Forensic Science: DNA extraction from trace biological evidence (e.g., bloodstains, buccal swabs, hair follicles) with minimized shearing and thermal degradation
- Cell Biology: Mitochondrial and nuclear fractionation from cultured mammalian cells using differential centrifugation protocols
- Virology: Concentration of lentiviral or AAV vectors from conditioned media without compromising infectivity titer
FAQ
What is the minimum sample volume supported by the M1324?
The centrifuge is calibrated for optimal performance with volumes ranging from 0.2 mL to 2.0 mL per tube. Minimum effective volume depends on rotor geometry and tube type; use manufacturer-recommended tubes for guaranteed RCF delivery.
Does the M1324 meet international regulatory standards for clinical use?
Yes—the device carries CE marking under the EU Medical Device Regulation (MDR) Annex II Class I criteria for ancillary diagnostic equipment and conforms to ISO 15189:2022 requirements for pre-analytical instrumentation in accredited laboratories.
Can third-party rotors be installed?
No. Only RWD-certified fixed-angle rotors (e.g., FA-24×2) are validated for safety, balance, and thermal performance. Unauthorized rotor installation voids warranty and violates IEC 61010-2-020 compliance.
How often does the refrigeration system require maintenance?
Under normal operating conditions (≤8 hrs/day, ambient ≤30°C), the sealed compressor requires no scheduled servicing for 5 years. Condenser coil cleaning is recommended quarterly in high-dust environments.
Is rotor lifetime tracked automatically?
Yes—each rotor contains an RFID tag that logs cumulative run time, maximum speed history, and thermal cycles. This data is accessible via the touch interface and exported during protocol audits.
