Sanotac ZS1020 High-Pressure Dual-Piston Constant Flow Pump for Microreactor Systems
| Brand | Sanotac |
|---|---|
| Model | ZS1020 |
| Flow Range | 0.01–100.00 mL/min |
| Flow Increment | 0.01 mL/min |
| Flow Accuracy | ±0.5% |
| Flow Precision (RSD) | ≤0.1% |
| Max Pressure | 20 MPa |
| Pressure Pulsation | ≤0.2 MPa |
| Pump Head Material | 316L Stainless Steel, Sapphire, PTFE, Ceramic |
| Tubing Connection | 1/16" Standard Fitting |
| Display | 256×64 Dot Matrix Backlit LCD |
| Control Interface | Front Panel Keypad + RS232/USB Computer Remote Control (Open Protocol) |
| Power Supply | 85–264 VAC, 50 Hz |
| Dimensions | 370 × 240 × 152 mm |
Overview
The Sanotac ZS1020 is a high-precision, dual-piston constant flow pump engineered specifically for integration with microreactor systems, continuous flow synthesis platforms, and high-pressure laboratory reactors. It operates on positive displacement principle using parallel dual-piston architecture with floating piston design—ensuring consistent volumetric delivery under variable backpressure conditions up to 20 MPa. Unlike peristaltic or diaphragm-based pumps, the ZS1020 delivers true constant flow independent of fluid viscosity, compressibility, or system resistance, making it suitable for demanding applications such as nitration, fluorination, carbonylation, diazotization, and other exothermic or hazardous chemical transformations where precise stoichiometric control and pressure stability are critical.
Key Features
- Dual-piston parallel drive system with real-time solvent compressibility compensation—minimizes flow deviation across wide dynamic range (0.01–100.00 mL/min)
- Floating piston mechanism reduces mechanical stress on sealing components, extending seal lifetime and maintaining long-term pressure integrity
- Multi-point flow calibration curve correction ensures linearity and accuracy at both low and high flow rates
- Cam profile optimization combined with electronic pulse suppression lowers pressure pulsation to ≤0.2 MPa (RMS), critical for stable residence time distribution in microchannels
- High-reliability fluid path constructed from 316L stainless steel, sapphire check valves, PTFE seals, and ceramic wear surfaces—compatible with strong acids (e.g., HNO₃, H₂SO₄), strong bases (e.g., NaOH, KOH), halogenated solvents, and oxidizing reagents
- Open communication protocol (RS232/USB) enables seamless integration with third-party chromatography data systems (CDS), PLC controllers, or custom LabVIEW/Python automation frameworks
- 10 pre-programmable user methods support complex gradient profiles—including isocratic, linear, stepwise, and composite gradients—for multi-step reaction sequencing
Sample Compatibility & Compliance
The ZS1020 is validated for use with corrosive, viscous, and particulate-laden process streams typical in fine chemical synthesis and pharmaceutical intermediate manufacturing. Its wetted materials comply with ASTM F2136 (biocompatibility of elastomers) and ISO 10993-5 (cytotoxicity testing). The pump meets CE marking requirements for electromagnetic compatibility (EMC Directive 2014/30/EU) and low-voltage safety (LVD Directive 2014/35/EU). For regulated environments, optional audit trail logging and user access control can be implemented via external SCADA or LIMS interfaces to support GLP/GMP-aligned workflows per FDA 21 CFR Part 11 when paired with compliant software infrastructure.
Software & Data Management
While the ZS1020 operates autonomously via its built-in keypad and backlit LCD interface, its open-command protocol allows full remote operation—including real-time flow/pressure setpoint adjustment, method upload/download, and status monitoring—through standard serial or USB connections. Engineers may develop custom control scripts in Python, MATLAB, or LabVIEW using documented ASCII command sets. No proprietary driver installation is required. Optional firmware upgrades are delivered via secure firmware update package (FUP) format, ensuring traceable version control and validation readiness.
Applications
- Continuous-flow synthesis of APIs and agrochemical intermediates requiring strict residence time control
- High-pressure hydrogenation, oxidation, and photochemical reactions in chip-based or tubular microreactors
- Feedstock delivery for supercritical fluid processing (e.g., scCO₂ extraction, impregnation)
- Calibration reference pump in metrology labs verifying flowmeter accuracy per ISO 4064-2
- Process analytical technology (PAT) integration for real-time feed-forward control loops in QbD-compliant manufacturing
- On-demand reagent dosing in automated parallel synthesis stations with multi-pump synchronization capability
FAQ
What is the maximum allowable inlet pressure for the ZS1020?
The pump is designed for atmospheric or slightly pressurized inlet conditions (≤0.5 MPa); upstream pressurization beyond this limit may compromise check valve performance and void warranty.
Can the ZS1020 handle slurries or abrasive suspensions?
No—it is intended for homogeneous liquid-phase delivery only; particulates >5 µm risk damaging sapphire valves and ceramic plunger surfaces.
Is firmware upgrade supported in-field?
Yes, via USB memory stick using signed firmware update packages traceable to Sanotac’s version-controlled release repository.
Does the pump meet explosion-proof requirements for Zone 1 environments?
The standard ZS1020 is not ATEX-certified; however, Sanotac offers an intrinsically safe variant (ZS1020-EX) with IECEx/ATEX certification for hazardous area deployment.
How is flow accuracy verified during IQ/OQ qualification?
Sanotac provides a certified gravimetric test report (traceable to NIST standards) and supports user-executed verification using Class I analytical balances and temperature-compensated density tables per USP .
