Sartorius BSA224S and BSA224S-CW Advanced Analytical Balances

Overview

The Sartorius BSA224S and BSA224S-CW are high-precision analytical balances engineered for routine and regulated laboratory environments where trace-level mass determination is critical. Operating on electromagnetic force compensation (EMFC) principle, these balances deliver stable, drift-compensated measurements with a readability of 0.1 mg across a 220 g maximum capacity. Designed and manufactured in Germany, the BSA series integrates thermally stable monolithic sensor architecture and advanced digital filtering algorithms to minimize environmental influence—such as air currents, temperature gradients, and vibration—ensuring consistent performance under standard ISO Class 5 (Class 100) laboratory conditions. The dual-model configuration addresses distinct operational requirements: the BSA224S relies on external calibration using certified weights, while the BSA224S-CW incorporates a motorized internal calibration mechanism with automatic temperature-triggered recalibration (ATC), enhancing measurement continuity in dynamic lab settings.

Key Features

• Electromagnetic force compensation (EMFC) transducer with zero-point stabilization and auto-zero tracking
• High-resolution 0.1 mg readability and ≤0.1 mg repeatability (standard deviation over 10 consecutive weighings under controlled conditions)
• Internal calibration (BSA224S-CW) includes integrated weight and ATC logic—recalibrates automatically when ambient temperature shifts exceed ±1.5 °C from last calibration
• External calibration option (BSA224S) supports traceable adjustment using Class E2 or better reference weights per OIML R111
• 90 mm stainless steel weighing pan with optimized geometry for minimal air turbulence and rapid settling time (<2 s typical)
• Integrated draft shield compatibility (optional BSA-DSC kit) meeting ISO 9001 and ISO/IEC 17025 environmental control requirements
• RS232 and USB interfaces compliant with ASTM E2656 for instrument data export; optional Ethernet module available for network integration

Sample Compatibility & Compliance

The BSA224S and BSA224S-CW accommodate a broad range of sample types—including powders, granules, liquids in tared vessels, and small solid components—within standard analytical workflows. Weighing chamber dimensions (when used with optional draft shield) support containers up to 120 mm height and 80 mm diameter. Both models meet essential metrological requirements defined in USP “Balances” for pharmaceutical testing, including repeatability, eccentricity, and linearity verification protocols. They are fully compatible with GLP and GMP documentation frameworks: audit trail logging (via optional Sartorius LabX software), user access control, electronic signatures (21 CFR Part 11 compliant when paired with validated LabX), and calibration certificate generation aligned with ISO/IEC 17025 clause 6.5.

Software & Data Management

Sartorius LabX™ software (sold separately) provides full lifecycle management—from method creation and instrument control to raw data archiving and report generation. LabX enforces role-based permissions, automated calibration scheduling, and real-time deviation alerts during weighing. All balance events—including zeroing, taring, calibration, and result entry—are timestamped and logged with operator ID and reason-for-change metadata. Data exports comply with CSV, PDF, and XML formats, supporting LIMS and ELN integration via configurable API endpoints. Local standalone operation is supported via built-in alphanumeric keypad and high-contrast backlit LCD display with intuitive icon-driven navigation.

Applications

These balances serve core functions across quality control laboratories in pharmaceuticals (e.g., active pharmaceutical ingredient (API) assay, excipient blending verification), chemical synthesis (reaction stoichiometry validation, catalyst dosing), food safety testing (nutrient labeling compliance, moisture content by loss-on-drying), and academic research (nanomaterial mass quantification, gravimetric titration). Their stability and reproducibility make them suitable for applications requiring adherence to ISO 17025-accredited test methods, including ASTM D1983 (determination of ash content), ISO 11885 (heavy metal analysis by ICP-OES sample preparation), and pharmacopeial general chapters such as USP “Weighing on an Analytical Balance”.

FAQ

What is the difference between BSA224S and BSA224S-CW?
The BSA224S requires manual external calibration using certified weights, whereas the BSA224S-CW features an integrated motorized calibration weight and automatic temperature-triggered recalibration.
Is the balance compliant with 21 CFR Part 11?
Yes—when operated with validated Sartorius LabX software, the system supports electronic signatures, audit trails, and secure user authentication required for FDA-regulated environments.
Can the balance be connected to a laboratory network?
Yes—via optional Ethernet interface module; RS232 and USB ports support direct PC connection and basic data transfer without additional hardware.
What draft shield options are available?
Sartorius offers the BSA-DSC modular draft shield system, designed specifically for BSA-series balances and compliant with ISO 9001 environmental control guidelines.
Does the balance support GLP-compliant record keeping?
Yes—through LabX software, which generates timestamped, immutable records of all weighing events, calibration actions, and user interventions, fulfilling GLP documentation integrity requirements.