Sartorius PRACTUM224-1CN Analytical Balance

Overview

The Sartorius PRACTUM224-1CN is a high-performance analytical balance engineered for precision mass measurement in regulated laboratory environments. Designed and manufactured in Germany, it operates on electromagnetic force compensation (EMFC) principle—where the weight of a sample generates a proportional current in a coil suspended within a permanent magnetic field; the resulting restoring force is digitally quantified to deliver highly reproducible mass readings. With a maximum capacity of 220 g and readability of 0.1 mg (i.e., 0.0001 g), this balance meets the stringent requirements of analytical chemistry, pharmaceutical quality control, and academic research workflows where trace-level accuracy and long-term stability are critical. Its robust mechanical architecture—including a monolithic weighing sensor, reinforced die-cast housing, and integrated draft shield—ensures consistent performance under variable ambient conditions, including minor air currents and thermal fluctuations common in shared lab spaces.

Key Features

• Electromagnetic force compensation (EMFC) transducer delivering high linearity and minimal drift over time
• Integrated draft shield with practical front-access sliding doors and ergonomic handle design for rapid sample loading
• Bottom-loading hook for below-balance weighing applications (e.g., density determination, magnetic susceptibility testing)
• Large, backlit LCD display with intuitive icon-based navigation and multilingual interface support (English, German, French, Spanish, Chinese)
• USB-B port compliant with virtual COM port protocol for direct data streaming to Microsoft Excel, LIMS, or ELN systems without proprietary software
• Programmable auto-print function with configurable time intervals for real-time documentation of dynamic weighing processes
• Regulatory lock feature enabling administrators to restrict access to calibration, configuration, and unit settings—essential for student labs and GxP training environments
• Front-mounted leveling bubble and oversized leveling feet ensure rapid, tool-free horizontal alignment—critical for measurement integrity per ISO 17025 Clause 6.4.1

Sample Compatibility & Compliance

The PRACTUM224-1CN accommodates standard laboratory vessels—including weighing boats, crucibles, volumetric flasks, and small reaction vials—within its Ø90 mm stainless-steel pan and 209 mm vertical clearance. Its draft shield design conforms to ISO 9001 and supports routine verification per USP “Balances” and EP 2.1.7 guidelines. The balance is fully compatible with internal and external calibration protocols required by ISO/IEC 17025-accredited laboratories and satisfies foundational data integrity expectations outlined in FDA 21 CFR Part 11 when used with validated data capture methods. While not equipped with built-in internal calibration, its external calibration workflow supports traceability to NIST-traceable standards via Class E2 or F1 weights.

Software & Data Management

Data export is implemented via native USB CDC (Communication Device Class) mode, eliminating driver dependencies and enabling plug-and-play integration with Windows, macOS, and Linux platforms. All measurements—including timestamp, net/gross/tare values, and stability status—are transmitted as ASCII-formatted strings, allowing seamless ingestion into spreadsheet applications or custom database scripts. Audit trail functionality is maintained externally through host-system logging; for full ALCOA+ compliance (Attributable, Legible, Contemporaneous, Original, Accurate), users are advised to pair the balance with validated electronic lab notebook (ELN) or LIMS solutions that enforce user authentication and change control. Firmware updates are delivered via Sartorius’ official service portal and require authorized technician access.

Applications

• Quantitative gravimetric analysis in pharmaceutical QC labs (e.g., active ingredient assay, excipient blending verification)
• Preparation of standard solutions and reference material dilutions per ISO/IEC 17034 requirements
• Weighing of catalysts, nanoparticles, and micro-dosed reagents in materials science research
• Density determination of solids and liquids using sinker or pycnometer methods
• Educational use in undergraduate chemistry and physics laboratories requiring GxP-aware instrumentation
• Environmental testing labs performing filter weighing for particulate matter (PM_2.5/PM₁₀) analysis per EPA Method 201A

FAQ

Does the PRACTUM224-1CN support internal calibration?
No—it relies exclusively on external calibration using certified weights. Internal calibration is available only in higher-tier QUINTIX and SECURA models.
Is the USB interface compatible with modern operating systems?
Yes—the device enumerates as a standard CDC ACM class serial port and requires no additional drivers on Windows 10/11, macOS 12+, or recent Linux kernels.
What is the recommended calibration frequency?
Per ISO/IEC 17025, calibration interval must be risk-assessed based on usage intensity, environmental stability, and criticality of measurement; typical practice ranges from daily zero-checks to weekly full-range verification.
Can the regulatory lock be disabled remotely?
No—unlocking requires physical access and entry of an administrator PIN at the front panel; no network or software override is possible.
Is the balance suitable for ISO Class 5 cleanroom environments?
Yes—the sealed electronics, smooth surfaces, and absence of ventilation grilles permit safe operation in controlled environments when used with appropriate static-dissipative workbenches.