SCIWAY ZNG2000 Series Membrane-Based Nitrogen Generator

Overview

The SCIWAY ZNG2000 Series Membrane-Based Nitrogen Generator is an engineered solution for laboratories requiring continuous, on-demand supply of high-purity nitrogen gas (99.9%) to support critical analytical instrumentation. Utilizing hollow-fiber membrane separation technology, the system selectively permeates oxygen, water vapor, and other trace gases from compressed air—retaining nitrogen with consistent purity and minimal pressure drop. Unlike pressure swing adsorption (PSA) systems, the ZNG2000 operates without molecular sieves, cycling valves, or regeneration phases, delivering inherently stable output flow and pressure over extended operational periods. It is specifically optimized for LC-MS, GC-MS, ICP-MS, and other mass spectrometry platforms requiring ultra-dry, oil-free, particle-free nitrogen for nebulization, drying, collision gas, or source purge applications. Its compact footprint and integrated refrigerated dryer make it suitable for deployment in humidity-variable environments common across East Asian laboratories, where ambient dew points frequently exceed 20 °C.

Key Features

• Hollow-fiber membrane module with certified long-life performance—no consumable adsorbents or scheduled sieve replacement required
• Integrated refrigerated air dryer achieving a consistent −20 °C pressure dew point, eliminating condensation risk downstream of the generator
• 30-L stainless steel buffer tank mitigates pressure fluctuations and reduces compressor cycling frequency—extending service life of upstream air compressors
• Low-noise operation (<58 dBA at 1 m), compliant with ISO 7779 and ANSI S12.55 standards for laboratory ambient noise control
• Modular chassis with industrial-grade casters enables flexible repositioning within constrained lab spaces without permanent mounting
• Minimal external plumbing: single inlet air connection and one nitrogen outlet port—reducing leak points and simplifying validation documentation
• Front-access service panel with tool-free component access for routine maintenance of filter elements and dryer condensate drain

Sample Compatibility & Compliance

The ZNG2000 is validated for seamless integration with major LC-MS platforms including AB SCIEX TripleTOF®, Agilent 6400/6500 series, Waters Xevo TQ-S, Thermo Fisher Scientific Q Exactive™ and Orbitrap™ systems, and Shimadzu Nexera UC/UHPLC-MS/MS. All wetted surfaces contacting nitrogen are electropolished 316L stainless steel or FDA-compliant fluoropolymer-lined components. The system meets ISO 8573-1:2010 Class 2 specifications for particulate, moisture, and oil content in instrument-grade gases. While not certified under FDA 21 CFR Part 11, its hardware architecture supports audit-trail-ready data logging when interfaced with compliant third-party SCADA or LIMS systems. Documentation packages include Factory Acceptance Test (FAT) reports, material certifications (EN 10204 3.1), and calibration certificates traceable to NIST standards.

Software & Data Management

The ZNG2000 operates as a standalone, microprocessor-controlled unit with no embedded operating system or remote connectivity. Real-time status indicators (flow, pressure, dew point, dryer temperature) are displayed via a backlit LCD interface with tactile keypad navigation. All operational parameters are logged internally at 1-minute intervals for up to 30 days and exportable via USB-C port in CSV format. Optional analog (4–20 mA) and digital (RS-485 Modbus RTU) outputs enable integration into facility-wide gas monitoring networks. No proprietary software installation is required—data files are natively readable in Excel, LabVIEW, or ELN platforms supporting standard time-series ingestion protocols.

Applications

• Nebulizer and desolvation gas supply for electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) sources
• Cooling and collision gas for quadrupole, time-of-flight (TOF), and ion trap mass analyzers
• Carrier and makeup gas for GC-MS systems requiring inert, dry nitrogen
• Blank gas for zero-air generation systems when paired with catalytic purifiers
• Blanketing and inerting during sample preparation workflows involving volatile organic compounds (VOCs)
• Gas supply for nitrogen-purged optical enclosures and laser cavities requiring stable thermal profiles

FAQ

Does the ZNG2000 require periodic membrane replacement?
Membrane modules are rated for ≥20,000 hours of continuous operation under specified inlet air quality (ISO 8573-1 Class 2). Replacement is only necessary if inlet air contains excessive oil aerosol or particulates beyond filtration capacity.
Can the unit be installed in an unconditioned utility room?
Yes—the integrated refrigerated dryer and thermal management system allow stable operation at ambient temperatures from 5 °C to 40 °C and relative humidity up to 95% non-condensing.
Is the nitrogen output suitable for USP or EP 2.5.27 compliance?
While the ZNG2000 delivers 99.9% N₂ with −20 °C dew point, formal pharmacopeial compliance requires additional verification of total hydrocarbon content (<0.1 ppm) and residual oxygen (<100 ppm), which must be confirmed via on-site testing per user-defined SOPs.
What compressed air quality is required at the inlet?
Inlet air must meet ISO 8573-1:2010 Class 2 (≤0.1 µm particles, ≤0.1 mg/m³ oil, −40 °C pressure dew point) prior to entering the ZNG2000. A pre-filter station with coalescing and activated carbon stages is recommended.
Does the system support redundant operation or parallel configuration?
The ZNG2000 is designed for single-unit deployment. Parallel operation is not supported out-of-the-box but can be implemented using externally plumbed manifold systems with pressure-synchronized regulators and check valves.