Shanghai RightOne LHS-500CA Low-Temperature Temperature and Humidity Controlled Chamber
| Brand | Shanghai RightOne (ShYY) |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Upright Environmental Test Chamber |
| Cooling Method | Air-Cooled |
| Temperature Range | −10 °C to +80 °C |
| Humidity Range | 30–95% RH |
| Temperature Uniformity | ±0.5 °C |
| Humidity Uniformity | ±3% RH |
| Internal Chamber Dimensions | 700 × 700 × 1020 mm (W × D × H) |
Overview
The Shanghai RightOne LHS-500CA is a precision-engineered upright temperature and humidity controlled chamber designed for stable, long-term environmental simulation in scientific, biomedical, and industrial quality assurance laboratories. It operates on the principle of active thermoelectric and vapor compression cooling combined with resistive steam humidification and forced-air convection—enabling precise, independent control of both temperature and relative humidity across a broad operational envelope. Engineered for reproducibility and regulatory readiness, the LHS-500CA meets foundational requirements for storage validation per ISO 14644-3 (cleanroom environmental monitoring), ICH Q5C (stability testing of biopharmaceuticals), and WHO Technical Report Series No. 992 (guidelines on good manufacturing practices for pharmaceutical products). Its −10 °C to +80 °C temperature range and 30–95% RH capability support applications ranging from vaccine cold chain integrity verification to accelerated aging studies of electronic components under thermal-hygric stress.
Key Features
- Microprocessor-based PID dual-loop control system with 5.7-inch backlit LCD interface, supporting up to 99 programmable cycles, each with 30 configurable segments (max. 99 h 59 min per segment)
- Double-door structure featuring tempered glass observation window with silicone-sealed gasket, minimizing thermal leakage during visual inspection
- Interior chamber constructed from electropolished mirror-finish stainless steel (SUS304), with radius-rounded corners and adjustable stainless-steel shelving (standard: 3 shelves; max: 25)
- Environmentally compliant refrigerant system using R134a/R406a blend; energy-efficient air-cooled condenser with low-noise axial fans
- Integrated humidity generation via stainless-steel immersion heater in self-contained water reservoir, paired with Vaisala or equivalent capacitive RH sensor (traceable calibration available)
- Optimized airflow architecture with rear-mounted centrifugal blower and directional ducting to ensure ≤±0.5 °C spatial uniformity (measured at 9 points per IEC 60068-3-5)
- Four-point leveling system with dual-mode mobility: swivel casters (locking) + adjustable leveling feet for vibration-isolated placement
Sample Compatibility & Compliance
The LHS-500CA accommodates diverse sample formats—including stacked cryovials, multi-well plates, serum bags, PCB assemblies, polymer films, and sealed reference standards—within its 500 L working volume (700 × 700 × 1020 mm). Its stainless-steel interior and non-outgassing materials comply with USP for container suitability assessment. For regulated environments, optional accessories enable compliance with FDA 21 CFR Part 11 (via RS485/USB data logging with audit trail-enabled software), GLP/GMP documentation workflows, and ASTM E2875-22 (standard guide for environmental chamber qualification). The unit is certified to GB/T 10586-2018 (Chinese national standard for environmental test chambers) and CE-marked per EN 61000-6-3 (EMC) and EN 61000-6-2 (immunity).
Software & Data Management
When equipped with the optional USB/RS485 interface and proprietary data acquisition software, the LHS-500CA supports continuous real-time logging of temperature, humidity, setpoint deviation, alarm status, and cycle progression. Export formats include CSV and PDF reports compliant with ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available). Data encryption, user role-based access control (admin/operator), and electronic signature capability are available under the full GxP software package. Optional embedded thermal printer provides hard-copy traceability for critical stability runs without external peripherals.
Applications
- Biological sample preservation: plasma, stem cells, viral vectors, and mRNA vaccines requiring sub-zero stabilization
- Pharmaceutical stability testing per ICH Q1A(R3) under intermediate (30 °C/65% RH) and accelerated (40 °C/75% RH) conditions
- Electronics reliability screening: moisture sensitivity level (MSL) testing per J-STD-020 and thermal cycling per JEDEC JESD22-A104
- Material science: hygrothermal aging of composites, adhesives, and packaging films per ASTM D5229/D5229M
- Quality control in blood banks and CDC-affiliated labs for cold chain validation (e.g., WHO PQS criteria for cold boxes)
- Environmental simulation for sensor calibration, catalyst performance evaluation, and corrosion testing (ISO 9223)
FAQ
What is the validated temperature and humidity uniformity across the working chamber?
Per IEC 60068-3-5 methodology, uniformity is ≤±0.5 °C (temperature) and ≤±3% RH (humidity) at steady state, measured at nine locations including corners and center.
Does the unit support IQ/OQ/PQ documentation packages?
Yes—factory-supplied qualification templates (in English) aligned with ISO/IEC 17025 and Annex 15 of EU GMP are available upon request.
Can the chamber operate continuously at −10 °C with 30% RH?
Yes—the refrigeration and dehumidification systems are co-optimized for simultaneous low-temperature, low-humidity operation without frost accumulation or sensor drift.
Is remote monitoring supported out of the box?
Standard configuration includes local display only; Ethernet/WiFi connectivity requires the optional RS485-to-Ethernet gateway and software license.
What maintenance intervals are recommended for optimal performance?
Compressor oil and refrigerant pressure checks annually; humidity sensor recalibration every 6 months; condensate tray cleaning weekly; air filter replacement every 3 months.
