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Shanghai Xiyu XYN-500 High-Purity Nitrogen Generator

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Brand XiYou
Origin Shanghai, China
Model XYN-500
Nitrogen Generation Principle Membrane Separation (MEM)
Output Flow Rate 0–500 mL/min
Output Pressure 0–0.5 MPa (factory-set at 0.4 MPa)
Nitrogen Purity O₂ < 3 ppm
Dew Point < −70 °C
Power Consumption 100 W
Dimensions (W×D×H) 330 × 220 × 350 mm
Net Weight < 22 kg

Overview

The Shanghai Xiyu XYN-500 High-Purity Nitrogen Generator is an engineered solution for laboratories and analytical facilities requiring a continuous, reliable, and safe source of high-purity nitrogen gas. Unlike traditional compressed gas cylinders, the XYN-500 utilizes membrane separation (MEM) technology to extract nitrogen from ambient compressed air—eliminating logistical constraints, safety hazards associated with high-pressure storage, and operational downtime caused by cylinder changeovers. The system delivers nitrogen with oxygen content below 3 ppm and a dew point lower than −70 °C, meeting stringent requirements for carrier gas in gas chromatography (GC), purge-and-trap systems, LC-MS interface drying, and inert atmosphere applications in sample preparation and material handling. Its compact footprint (330 × 220 × 350 mm) and low power draw (100 W) make it suitable for benchtop integration in QC labs, research environments, and regulated manufacturing settings where space efficiency and energy economy are critical.

Key Features

  • Membrane-based nitrogen generation ensures consistent purity without consumables, catalysts, or routine replacement parts—reducing total cost of ownership over time.
  • Integrated pressure regulation and automatic shut-off upon power loss prevent backflow and maintain system integrity during unexpected outages.
  • Stainless-steel housing and corrosion-resistant internal components support long-term reliability under continuous operation.
  • Front-panel digital display provides real-time monitoring of output pressure and flow rate, enabling precise adjustment within the 0–0.5 MPa and 0–500 mL/min operating ranges.
  • Low-heat design minimizes thermal drift and enhances stability of downstream instrumentation reliant on consistent gas supply.
  • Factory-calibrated at 0.4 MPa output pressure—optimized for compatibility with standard GC inlets, ECD detectors, and nitrogen-purged glove boxes.

Sample Compatibility & Compliance

The XYN-500 is compatible with all laboratory-grade compressed air sources meeting ISO 8573-1 Class 2:2:2 specifications (oil-free, particulate-free, dew point ≤ −40 °C). It does not require external dryers or filters when fed with appropriately conditioned air. While not certified to ISO/IEC 17025 or CE for standalone metrological traceability, its performance parameters align with common instrument gas specifications defined in ASTM D6299 (for GC carrier gas quality) and USP (for inert gas purity in pharmaceutical analysis). For GLP/GMP environments, users may implement internal validation protocols—including periodic verification of O₂ impurity via electrochemical sensor or paramagnetic analyzer—and document maintenance per 21 CFR Part 11-compliant data management practices.

Software & Data Management

The XYN-500 operates as a stand-alone hardware unit with no embedded firmware or software interface. All operational parameters are controlled manually via front-panel knobs and monitored via analog/digital indicators. This architecture eliminates cybersecurity vulnerabilities, firmware update dependencies, and compatibility conflicts with legacy lab networks. For labs requiring audit-ready records, integration with external Building Management Systems (BMS) or Lab Information Management Systems (LIMS) can be achieved using optional 4–20 mA analog output modules (sold separately), enabling remote logging of pressure and flow status. Internal event logging is not supported; however, the unit’s mechanical robustness and stable output characteristics support routine qualification testing per IQ/OQ protocols.

Applications

  • Carrier and makeup gas for capillary GC and GC-MS systems requiring O₂-free, low-dew-point nitrogen.
  • Inert blanketing during solvent evaporation, lyophilization, and reactive chemical synthesis.
  • Purge gas for FTIR sample compartments, XRD sample stages, and electron microscopy specimen chambers.
  • Zero-air generation support when paired with catalytic oxidizers for calibration gas standards.
  • Continuous nitrogen supply for automated sample introduction systems (e.g., autosamplers, headspace injectors) where cylinder dependency introduces scheduling risk.

FAQ

What compressed air quality is required for optimal XYN-500 performance?

Ambient air must be supplied through an oil-free compressor and pre-filtered to remove particulates, moisture, and hydrocarbons. A coalescing filter + desiccant dryer delivering ISO 8573-1 Class 2:2:2 air is strongly recommended.
Can the XYN-500 be used as a backup for existing nitrogen pipelines?

Yes—its 0.5 MPa maximum output pressure allows seamless integration into low-pressure lab distribution networks, provided pressure regulators and check valves are installed to prevent backfeed.
Does the unit require periodic recalibration?

No built-in sensors require calibration; however, users should verify nitrogen purity annually using an independent O₂ analyzer per internal SOP or regulatory requirement.
Is the XYN-500 compliant with FDA 21 CFR Part 11?

As a non-networked, non-data-logging device, it does not fall under electronic record/electronic signature scope—but its stable output supports Part 11-aligned validation workflows when paired with compliant data capture tools.
What maintenance is required beyond routine filter replacement?

No scheduled maintenance is specified beyond replacing inlet air filters every 6–12 months based on usage and ambient conditions. The membrane module has a typical service life exceeding 10,000 hours under rated load.

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