Shen’an LDZM-80L / LDZM-80L-I Vertical Stainless Steel Steam Autoclave (80 L)

Overview

The Shen’an LDZM-80L and LDZM-80L-I are vertically oriented, Class B steam autoclaves engineered for reliable, repeatable moist-heat sterilization in academic laboratories, clinical diagnostics facilities, pharmaceutical QC labs, and biomedical research environments. These units operate on the fundamental principle of saturated steam under controlled pressure to achieve microbial inactivation—primarily targeting bacterial spores (e.g., Bacillus stearothermophilus) through thermal denaturation of proteins and nucleic acids. With a certified chamber volume of 80 liters and a maximum operating temperature of 134 °C at 0.217 MPa (≈2.2 bar gauge), both models comply with ISO 17665-1:2017 (Sterilization of health care products — Moist heat — Part 1: Requirements for the development, validation and routine control of a sterilization process for medical devices) and align with national pressure vessel safety standards (TSG 21–2016 and GB/T 150). The LDZM-80L is a microprocessor-controlled unit with manual initiation and automated cycle execution; the LDZM-80L-I adds full automation—including programmable start delay, auto-air removal, real-time parameter logging, and integrated safety interlocks—making it suitable for GLP/GMP-aligned workflows requiring audit-ready documentation.

Key Features

• Robust 304 stainless steel sterilization chamber (wall thickness ≥2 mm) with electropolished interior for corrosion resistance and ease of cleaning.
• Dual-safety pressure protection: mechanical safety valve + electronic overpressure cutoff, both independently validated per ASME BPVC Section VIII requirements.
• Self-sealing gasket design with automatic expansion under pressure ensures leak-tight integrity throughout the sterilization cycle.
• Multi-link lever mechanism enables smooth, low-effort lid actuation while maintaining precise alignment between flange and chamber seal surface.
• LCD graphical interface with intuitive scroll-based menu navigation supports one-touch parameter entry for temperature (50–134 °C), time (0–99 h), and cycle selection.
• Fan-assisted post-cycle cooling reduces chamber cooldown time by up to 40%, minimizing operator wait time before load retrieval.
• Integrated cold-air purge function eliminates non-condensable gases prior to steam saturation—critical for achieving uniform thermal distribution (validated per ISO 11140-1).
• Electronic–mechanical interlock system prevents lid opening when internal pressure exceeds 0.02 MPa, meeting EN 285:2015 safety mandates.
• Comprehensive fault diagnostics with on-screen error codes and audible alerts for dry-run, overtemperature, overpressure, door misalignment, and sensor drift.
• Optional thermal printer (RS232 or USB) provides traceable hardcopy records including date/time stamp, setpoints, actual chamber temperature/pressure profiles, and cycle completion status—supporting FDA 21 CFR Part 11 compliance when paired with secure user access controls.

Sample Compatibility & Compliance

The LDZM-80L series accommodates standard laboratory loads including wrapped instrument sets, porous materials (e.g., gauze, cotton rolls), liquids in vented containers, and microbiological media. Chamber geometry (Ø350 × 700 mm) allows stacking of two included stainless steel baskets (Ø335 × 190 mm and Ø335 × 360 mm), enabling efficient batch processing without compromising steam penetration. All operational parameters adhere to national and international regulatory frameworks: design and fabrication conform to GB/T 150.1–2011 (Pressure Vessels) and TSG 21–2016 (Safety Technical Supervision Regulation for Fixed Pressure Vessels); sterilization performance validation follows ISO 17665-1 and Chinese Pharmacopoeia (ChP) General Chapter 9202. The validation port facilitates thermocouple insertion for temperature mapping (IQ/OQ/PQ), supporting qualification in regulated environments.

Software & Data Management

While the base unit operates via embedded firmware without external PC dependency, the LDZM-80L-I variant supports optional data export via serial or USB connection. Logged parameters—including real-time temperature, pressure, elapsed time, and alarm events—are timestamped and stored in non-volatile memory for ≥1,000 cycles. When equipped with the thermal printer module, outputs meet ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) for regulatory review. Firmware includes configurable password-protected user levels (Operator, Technician, Administrator) to restrict access to calibration, parameter override, and log deletion functions—essential for maintaining data integrity in audited settings.

Applications

These autoclaves serve core sterilization needs across multiple domains: decontamination of reusable surgical instruments in university teaching hospitals; preparation of sterile culture media and buffers in molecular biology labs; terminal sterilization of glassware and plasticware in quality control departments; and routine bioburden reduction in tissue culture facilities. Their precision temperature control and validated air removal capability make them especially suitable for sterilizing heat-labile liquid formulations where extended exposure at lower temperatures (e.g., 121 °C for 20 min) must be tightly maintained. The vertical configuration optimizes floor space utilization—a key consideration in high-density lab layouts.

FAQ

What is the difference between LDZM-80L and LDZM-80L-I?
The LDZM-80L features microprocessor-based cycle control with manual start and automatic execution; the LDZM-80L-I adds programmable delayed start, fully automated air removal, continuous data logging, and optional printer integration.
Does this autoclave meet international sterilization standards?
Yes—it complies with ISO 17665-1:2017, EN 285:2015, and Chinese national standards GB/T 150 and TSG 21 for pressure equipment design and operation.
Can I validate the sterilization cycle using third-party software?
Yes—the built-in validation port accepts calibrated thermocouples for temperature mapping during Installation Qualification (IQ) and Operational Qualification (OQ) studies.
Is the chamber suitable for liquid sterilization?
Yes—equipped with slow-cool and liquid-specific cycle modes to prevent boil-over; recommended for aqueous solutions in vented containers only.
What safety certifications does the unit hold?
It carries mandatory Chinese Special Equipment Manufacturing License (Pressure Vessel Category I), and its pressure containment system is certified per TSG 21–2016 and GB/T 150.1–2011.