Shimadzu LC-2010CHT Refurbished High-Performance Liquid Chromatograph

Overview

The Shimadzu LC-2010CHT is a fully integrated, refurbished high-performance liquid chromatography (HPLC) system engineered for rapid, reproducible, and robust analytical separation in regulated and research laboratory environments. Built on Shimadzu’s proven dual-piston parallel pump architecture and low-pressure gradient mixing technology, the LC-2010CHT delivers precise solvent delivery, high-pressure stability, and thermally controlled sample integrity—critical for method transfer, QC/QA workflows, and pharmaceutical stability-indicating assays. Its modular design integrates a vacuum membrane degasser (5-channel), low-pressure quaternary gradient unit, high-accuracy binary pump, refrigerated autosampler with 4 °C cooling capability, Peltier-heated/cooled column oven (±0.1 °C stability), and dual-wavelength UV-VIS detector—all governed by a dedicated system controller. As a fast HPLC platform, it supports method development acceleration without compromising resolution or retention time reproducibility, making it suitable for laboratories transitioning from conventional HPLC to higher-throughput operation while maintaining full compliance readiness.

Key Features

• Dual-plunger parallel pump system with active (10 µL) and auxiliary (5 µL) pistons for enhanced pulse dampening and flow accuracy across 0.001–5.0 mL/min at pressures up to 35.0 MPa
• Low-pressure quaternary gradient unit supporting four solvents with 0.1% incremental mixing ratio control and ±0.1% RSD gradient precision (acetone/water, 0.1–2 mL/min)
• Integrated 5-channel online degasser: four channels for mobile phase lines + one dedicated channel for autosampler wash solvent, each with 4 mL (mobile phase) or 2 mL (wash) capacity
• Refrigerated autosampler featuring direct-cooling mechanism (4–40 °C range), 350-position 1 mL vial tray, <0.3% RSD injection repeatability (10 µL), and <0.01% carryover (naphthalene test)
• Peltier-based column oven with pre-heating of mobile phase, temperature control range from 15 °C below ambient to 60 °C, and ±0.1 °C stability over time
• UV-VIS detector equipped with deuterium lamp source, 190–600 nm spectral range, 8 nm bandwidth, ±1 nm wavelength accuracy, and dual-channel simultaneous acquisition (e.g., 220 nm + 254 nm)

Sample Compatibility & Compliance

The LC-2010CHT accommodates standard 1–4 mL screw-thread or crimp-top vials and supports both narrow-bore (2.1 mm) and analytical (4.6 mm) columns up to 30 cm in length. Its hardware architecture meets foundational requirements for adherence to ISO/IEC 17025, USP , and ICH Q2(R2) guidelines for chromatographic method validation. While the system controller does not natively support 21 CFR Part 11 electronic signatures out-of-the-box, its data output format (ASCII .txt, .csv, and native .lcd) is compatible with validated third-party chromatography data systems (CDS) that provide audit trail, user access control, and electronic record retention per FDA and EMA regulatory expectations. All thermal and fluidic modules undergo factory refurbishment including pressure testing, leak verification, lamp energy calibration, and baseline noise/drift validation.

Software & Data Management

The LC-2010CHT operates via Shimadzu’s proprietary Class VP-based control software (v7.x or later), enabling method setup, sequence definition, real-time monitoring, peak integration, and report generation. Raw data files are stored in vendor-neutral formats suitable for long-term archival and secondary processing. The system exports peak tables, chromatograms, and instrument logs with timestamped metadata—including flow rate, pressure, column temperature, detector wavelength, and injection volume—for traceability. When interfaced with enterprise-grade CDS platforms (e.g., Waters Empower, Thermo Chromeleon, or Agilent OpenLab), full GLP/GMP compliance—including user authentication, change control, and electronic signature enforcement—can be implemented without modification to the LC-2010CHT hardware.

Applications

• Pharmaceutical QC release testing of APIs and finished dosage forms (e.g., assay, related substances, dissolution)
• Environmental analysis of pesticides, PAHs, and pharmaceutical residues in water and soil extracts
• Food safety testing for preservatives, sweeteners, mycotoxins, and adulterants
• Academic and industrial research requiring method robustness under variable mobile phase composition and temperature
• Stability-indicating assays where column temperature control and low carryover are essential for forced degradation studies

FAQ

Is this LC-2010CHT unit certified as refurbished by Shimadzu?

No—it is professionally refurbished by an ISO 9001-certified third-party service provider specializing in Shimadzu instrumentation. Each unit undergoes full functional verification, component replacement (pump seals, purge valves, lamp, flow cells), and performance qualification against original factory specifications.
Does the system include a computer and software license?

The base configuration includes only the hardware modules listed. A Windows-compatible PC and licensed Class VP software are available as optional add-ons; contact our technical sales team for bundle pricing and version compatibility details.
Can the LC-2010CHT be upgraded to support GPC/SEC or fluorescence detection?

Yes—the system features standard analog and digital I/O ports compatible with Shimadzu RF-20A fluorescence detectors and CBM-20A communication modules for integration with SEC software. GPC functionality requires additional column sets and calibration standards, not included in the base package.
What maintenance documentation accompanies the instrument?

Each unit ships with a complete refurbishment report, PQ (Performance Qualification) summary, calibration certificates for UV lamp intensity and flow accuracy, and a 12-month limited hardware warranty covering all refurbished components.
Is remote diagnostics supported?

Remote connectivity is enabled via Ethernet port and standard TCP/IP protocols. With customer-approved firewall configuration, our support engineers can perform secure remote troubleshooting using TeamViewer or equivalent tools—subject to signed remote access agreement.