VWR Jencons Adjustable Burette-Style Bottle Top Dispenser Model 613-4005
| Brand | VWR |
|---|---|
| Origin | Germany |
| Instrument Type | Manual Bottle Top Dispenser |
| Model | 613-4005 |
| Volume Range | 3–30 mL |
| Graduation Interval | 1.0 mL |
| Material | Borosilicate Glass Piston with Chemically Resistant PTFE/EPDM Seals |
| Sterilization | Autoclavable (121°C, 20 min) |
| Compatibility | GL40 & GL45 Bottle Threads |
| Chemical Resistance | Certified for HCl, HNO₃, NaOH, Acetone, Methanol, and other common organic solvents |
Overview
The VWR Jencons Adjustable Burette-Style Bottle Top Dispenser Model 613-4005 is a precision-engineered manual liquid handling instrument designed for repeatable, traceable, and contamination-free dispensing of reagents and standards in analytical, quality control, and research laboratories. Developed from the legacy Jencons platform—acquired by VWR International in 2008—the dispenser employs a calibrated glass piston within a chemically inert housing to deliver volumetric accuracy via positive displacement mechanics. Unlike air-displacement pipettes, this bottle top dispenser eliminates aerosol generation and minimizes operator-induced variability by decoupling volume setting from manual plunger actuation. Its burette-style vernier scale enables fine-tuned adjustment across the full 3–30 mL range with 1.0 mL graduation intervals, supporting applications requiring intermediate-to-high volume transfers where gravimetric or volumetric reproducibility is critical under ISO 8655-5 and ASTM E539 compliance frameworks.
Key Features
- Vernier-calibrated glass piston assembly ensures mechanical stability and long-term calibration retention
- Borosilicate glass piston and PTFE/EPDM sealing system certified for compatibility with concentrated mineral acids (e.g., 37% HCl, 69% HNO₃), 50% NaOH, and polar/non-polar organic solvents including acetone, methanol, acetonitrile, and chloroform
- Full-unit autoclavability at 121°C for 20 minutes—validated per ISO 17665-1—enabling sterile processing in microbiology and cell culture workflows
- GL40 and GL45 thread adapters included as standard, ensuring secure mounting on common laboratory reagent bottles without slippage or leakage under pressure
- CV ≤ 0.2% at nominal volume (per ISO 8655-5 testing protocol), verified using certified Class A volumetric flasks and analytical balances traceable to NIST standards
- Ergonomic lever handle with tactile feedback reduces repetitive strain during high-frequency dispensing cycles
Sample Compatibility & Compliance
The 613-4005 dispenser accommodates aqueous, acidic, alkaline, and organic media without degradation of sealing integrity or piston mobility. It meets material compatibility requirements outlined in USP , EU Pharmacopoeia Chapter 3.1, and DIN EN ISO 15223-1 for medical device labeling. Its construction supports GLP-compliant documentation: each unit carries a permanent laser-engraved serial number, and calibration certificates (available upon request) include uncertainty budgets calculated per GUM (JCGM 100:2008). The device is suitable for use in environments governed by FDA 21 CFR Part 11 when integrated into validated LIMS or ELN systems that enforce electronic audit trails for volume-setting changes.
Software & Data Management
As a fully manual, non-electronic instrument, the 613-4005 requires no firmware, drivers, or software integration. Volume settings are recorded manually in lab notebooks or digital logbooks; however, its consistent CV performance enables direct inclusion in SOPs requiring documented precision thresholds (e.g., “dispensing step must achieve CV ≤ 0.3% per ISO 8655-5”). For labs implementing digital workflow validation, the dispenser’s fixed graduation interval (1.0 mL) and low drift rate (<0.05% per 100 cycles) support periodic verification using reference weights and density-calculated volumes—data which may be imported into compliant ELN platforms such as LabArchives or Benchling for audit-ready reporting.
Applications
- Preparation of calibration standards and QC samples in ICP-MS, HPLC, and titration workflows
- Controlled addition of catalysts, buffers, or hazardous reagents in synthetic chemistry labs
- Dispensing of sterilized media or antibiotics in aseptic cell culture facilities
- High-volume dilution series in environmental testing (e.g., EPA Method 200.8 sample prep)
- Reagent distribution in clinical chemistry analyzers requiring batch consistency across multi-day runs
FAQ
Is the 613-4005 compatible with narrow-neck reagent bottles?
Yes—it includes interchangeable GL40 and GL45 adapters, and optional GL38 adapters are available separately for smaller-format containers.
Can the dispenser be recalibrated in-house?
While not field-serviceable, users may perform routine performance verification using gravimetric methods per ISO 8655-5 Annex C; formal recalibration requires return to an authorized VWR service center with ISO/IEC 17025-accredited capability.
Does it meet regulatory requirements for pharmaceutical manufacturing?
Yes—the materials, dimensional tolerances, and repeatability data align with ICH Q7 Annex 10 and EU GMP Annex 15 expectations for qualified liquid handling devices used in non-sterile and sterile API manufacturing steps.
What maintenance is required between autoclave cycles?
After each autoclave cycle, inspect the piston seal for deformation and lubricate the glass piston with silicone-free, USP-grade mineral oil (VWR Cat. No. 8000-100) to maintain smooth operation and prevent galling.
Is there a version with digital volume display?
Yes—VWR offers the Jencons Digital Adjustable Dispenser series (e.g., Model 263-029, 3–30 mL range), which provides LED readout and programmable dispensing modes compatible with GLP audit logging via RS-232 output.
