Yacheng YC-100 Multifunctional Extraction and Concentration Unit
| Brand | Yacheng / PILOTECH |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Product Origin | Domestic (China) |
| Model | YC-100 |
| Pricing | Upon Request |
Overview
The Yacheng YC-100 Multifunctional Extraction and Concentration Unit is an integrated pilot-scale system engineered for precise, scalable, and GMP-aligned processing of botanical materials. Designed around closed-loop vacuum-assisted thermodynamic principles, it combines simultaneous solvent extraction, thermal reflux, dynamic circulation concentration, and volatile oil recovery in a single stainless-steel architecture. The unit operates on a dual-mode principle: heat transfer via jacketed导热油 (thermal oil) circulation—ensuring uniform, pressure-free heating—and mass transfer enhancement through controlled vacuum evaporation (up to −0.08 MPa) and optional ultrasonic cavitation. This enables reproducible extraction of thermolabile phytoconstituents—including flavonoids, alkaloids, terpenes, and essential oils—from herbs, teas, fruits, and marine botanicals under ISO 22000–compatible hygienic conditions. Its 100 L working volume, ±2 °C temperature control accuracy, and 1.1–1.38 specific gravity concentration range make it suitable for process development, formulation optimization, and pre-clinical batch production in academic, pharmaceutical, nutraceutical, and functional food laboratories.
Key Features
- Integrated dual-function design: simultaneous extraction and vacuum concentration within one sealed system, eliminating cross-contamination and solvent loss.
- Triple-layer 100 L extraction vessel: inner polished SUS304 contact surface, middle thermal oil heating jacket (pressure-free), outer polyurethane insulation—enabling safe organic solvent processing (e.g., ethanol, ethyl acetate).
- Reflexive thermal cycling: equipped with a 3 m² tubular condenser and phase-separating oil-water separator for quantitative recovery of volatile aromatic oils (e.g., eucalyptol, limonene, menthol).
- Dynamic circulation evaporation: continuous liquid film renewal across heating surfaces mitigates fouling and maintains high heat transfer coefficients even at elevated viscosities (up to 1.38 g/mL).
- Modular ultrasonic enhancement (optional): focused 15–60 kHz transducers induce controlled acoustic cavitation, disrupting plant cell walls without thermal degradation—validated for enhanced yield of heat-sensitive actives (e.g., polyphenols, glycosides).
- Full-pressure-range operation: certified for stable performance under vacuum (−0.08 MPa), atmospheric, and mild positive pressure (≤0.3 MPa) conditions.
- Automated material handling: hydraulically assisted herb basket lift mechanism ensures residue-free discharge and operator safety per OSHA-compliant ergonomics.
- Comprehensive instrumentation: Omron PID temperature controller, calibrated vacuum gauge, sanitary-grade safety valve, and IP54-rated electrical cabinet with CE-marked components.
Sample Compatibility & Compliance
The YC-100 accommodates solid botanical matrices (5–20 kg/batch), including dried roots, leaves, flowers, seeds, and marine algae. It supports aqueous, hydroalcoholic (20–95% ethanol), and low-boiling organic solvent systems (e.g., acetone, dichloromethane) with full containment integrity. All wetted parts comply with ASME BPE-2023 surface finish standards (Ra ≤ 0.8 µm), and the system meets FDA 21 CFR Part 11 requirements for electronic record audit trails when paired with validated SCADA software. It is routinely deployed in GLP environments for method validation per USP , ISO 17025, and Chinese Pharmacopoeia 2020 Vol. IV protocols.
Software & Data Management
The unit integrates with optional Yacheng LabControl™ v3.2 software, providing real-time logging of temperature profiles, vacuum levels, condensate flow rates, and ultrasonic duty cycles. Data export complies with ASTM E2500-21 for traceability, supports CSV/Excel formats, and includes built-in calibration certificate templates aligned with ISO/IEC 17025 accreditation criteria. Audit trail functionality records user actions, parameter changes, and system events with time-stamped digital signatures—fully compliant with FDA 21 CFR Part 11 Subpart C for regulated laboratories.
Applications
- Process development of herbal injectables and oral liquid formulations (e.g., *Salvia miltiorrhiza*, *Ginkgo biloba* extracts)
- Recovery and standardization of tea polyphenols and citrus bioflavonoids under low-temperature vacuum
- Essential oil isolation from *Mentha haplocalyx*, *Citrus sinensis*, and *Cinnamomum cassia* using phase separation
- Solvent recycling loops for ethanol or acetone in continuous GMP pilot lines
- Comparative studies of ultrasonic vs. conventional maceration kinetics in university pharmacognosy labs
- Stability testing of concentrated botanical intermediates per ICH Q1A(R3)
FAQ
What is the maximum operating temperature of the thermal oil jacket?
The system is rated for continuous operation up to 180 °C, with safety interlocks preventing exceedance beyond setpoint.
Can the unit handle corrosive solvents such as HCl-acidified water or sodium hydroxide solutions?
No—SUS304 construction limits compatibility to non-oxidizing, pH 2–12 aqueous and alcoholic media; for aggressive chemistries, optional SUS316L upgrade is available.
Is validation documentation (IQ/OQ/PQ) provided?
Yes—Yacheng supplies customizable qualification protocols and factory-verified test reports meeting ISO 13485 and EU Annex 15 standards.
What cooling water specifications are required for the condenser?
Maximum inlet pressure: 0.3 MPa; flow rate: 3 t/h at ≤25 °C inlet temperature.
Does the ultrasonic module require separate cooling or maintenance?
The transducer assembly is air-cooled and requires no consumables; recommended preventive maintenance interval is 2,000 operational hours.
