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| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Alliance iS HPLC System |
| Instrument Type | Conventional High-Performance Liquid Chromatograph |
| Application Scope | General-purpose QC and routine analytical laboratories |
| Regulatory Alignment | Designed for compliance with 21 CFR Part 11, ISO/IEC 17025, USP <1058>, and GLP/GMP environments |
| Software Integration | Fully compatible with Waters Empower CDS (v3 or later) and Empower LMS |
| Column Recognition | Enabled via Waters eConnect HPLC columns with embedded RFID tags |
| Hardware Architecture | Integrated, standardized platform with tool-free fittings, color-coded solvent lines, and modular column manager with active temperature control |
| Diagnostics & Monitoring | Real-time system health monitoring via built-in status indicators, touch-screen guided workflows, and waters_connect System Monitoring integration |
| Maintenance Support | On-device guided troubleshooting, step-by-step maintenance prompts, and direct access to Waters Help Center |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | ACQUITY UPLC System |
| Instrument Type | Ultra-High Performance Liquid Chromatograph |
| Sample Introduction | Integrated autosampler with flow-through needle design (H-Class), nano/micro-flow capability (M-Class), or high-precision low-dead-volume architecture (I-Class) |
| Pressure Rating | Up to 15,000 psi (103 MPa) |
| Flow Rate Range | 0.001–2.0 mL/min (model-dependent) |
| Column Temperature Control | 5–90 °C |
| UV/Vis Detection Wavelength Range | 190–700 nm (with optional PDA or TUV detectors) |
| Data Acquisition Rate | Up to 100 Hz |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | ACQUITY APC System |
| Instrument Type | Ultra-High-Performance Liquid Chromatograph (UHPLC) for Polymer Analysis |
| Sample Introduction | Automated, Dual-Column Switching Capability |
| Solvent Management | Polymer-Optimized Quaternary Solvent Manager (p-QSM) with Six-Solvent Selection |
| Temperature Control | Column Compartment with Precise Thermal Stability |
| Detection Compatibility | RI, UV/PDA, MALS, dRI, Viscometry, and Third-Party Detectors |
| Software Integration | WinGPC UniChrom™ (PSS), Empower™ (Waters), 21 CFR Part 11–Compliant Audit Trail Support |
| Calibration | Pre-qualified APC Calibration Kits for Sub-10-min Runs and Daily Column Re-Calibration |
| Column Technology | BEH (Bridged Ethyl Hybrid) Particles with Rigid Macroporous Structure |
| Regulatory Alignment | Designed for GLP/GMP Environments |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | PATROL UPLC |
| Instrument Type | Real-time In-line/At-line UPLC-based PAT System |
| Regulatory Alignment | Designed for FDA QbD and ICH Guidelines |
| Deployment Mode | Integrated Process Analytical Technology (PAT) Platform |
| Operational Architecture | Fully Automated, 24/7 Unattended Operation |
| Diagnostics | On-board Self-Diagnostics with Remote Monitoring Capability |
| Connectivity | Ethernet/IP-enabled for Distributed Control System (DCS) and Manufacturing Execution System (MES) Integration |
| Software Compliance | Supports 21 CFR Part 11 Audit Trail, Electronic Signatures, and GLP/GMP Data Integrity Requirements |
| Sample Introduction | Configurable for At-line Flow-Through Cells or Direct In-line Probes (with Optional Valving & Filtration Modules) |
| Brand | Waters |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Alliance iS Bio HPLC System |
| Instrument Type | Conventional High-Performance Liquid Chromatograph (HPLC) |
| Application Scope | General-Purpose Biotherapeutic Quality Control |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Arc HPLC System |
| Instrument Type | Conventional High-Performance Liquid Chromatograph |
| Application Scope | General-Purpose LC Analysis |
| Software Compatibility | Empower™ (FDA 21 CFR Part 11 compliant) |
| Regulatory Alignment | USP <621>, ICH Q2(R2), ISO/IEC 17025, GLP/GMP-ready |
| Column Oven Temperature Range | Ambient to 85 °C |
| Gradient Delay Volume Compensation | Smart Gradient Start™ technology |
| Solvent Delivery | Quaternary solvent manager with Auto•Blend Plus™ pH/ion strength programming |
| Sample Injection | Low-residue needle-in-loop autosampler with configurable wash protocols |
| Column Switching | Optional integrated 3-column switching valve |
| Detection Options | UV/Vis and PDA detectors optimized for small-molecule analysis |
| Method Transfer Capability | Seamless migration from Alliance™ and other legacy HPLC platforms |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Arc Premier System |
| Instrument Type | Ultra-High Performance Liquid Chromatography (UHPLC) |
| Application Scope | General-purpose LC platform for metal-sensitive and challenging analytes |
| Key Technology | MaxPeak High-Performance Surface (HPS) |
| Column Compatibility | Optimized for 2.5 µm MaxPeak Premier columns |
| Regulatory Support | Compliant with FDA 21 CFR Part 11, USP <1058>, ISO/IEC 17025, GLP/GMP validation workflows |
| Software Platform | Empower CDS v3/v4, MassLynx MS software |
| Detector Options | TUV, PDA, FLR, ACQUITY QDa, SQD2, Xevo TQS-micro, Xevo TQS-cronos |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Breeze HPLC |
| Instrument Type | Conventional High-Performance Liquid Chromatograph |
| Configuration | Modular Benchtop HPLC Platform |
| Target Users | Academic Teaching Labs, Regulatory QC Laboratories, Early-Stage R&D Facilities |
| Software | Breeze™ Chromatography Data System (CDS) |
| Compliance Framework | Designed for GLP/GMP-aligned workflows |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | ACQUITY UPLC H-Class PLUS |
| Instrument Type | Ultra-High Performance Liquid Chromatograph (UHPLC/UPLC) |
| Application Scope | General-purpose LC platform supporting both legacy HPLC and modern UPLC methods |
| Compliance | Designed for GLP/GMP environments |
| Brand | Waters |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | ACQUITY UPLC H-Class Bio |
| Instrument Type | Ultra-Performance Liquid Chromatograph (UPLC) |
| Solvent Delivery | Quaternary Gradient System |
| Sample Introduction | Flow-Through Needle Autosampler |
| Temperature Control | Column Heater with Multi-Column Switching Capability |
| Detection Compatibility | UPLC-Optimized UV/Vis, PDA, Fluorescence, and Mass Spectrometry Detectors |
| Regulatory Support | 21 CFR Part 11–compliant software, GLP/GMP audit trail, method validation support per ICH Q2(R2) and USP <1058> |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | ACQUITY UPC² |
| Instrument Type | Convergence Chromatography System |
| Primary Mobile Phase | Compressed Carbon Dioxide (CO₂) |
| Compatible Detectors | UV/Vis, PDA, MS (via dedicated interfaces) |
| Injection Volume Range | 0.5–10 µL |
| Column Temperature Control | Ambient to 85 °C |
| System Pressure Range | Up to 15,000 psi (103 MPa) |
| Gradient Composition Accuracy | ≤0.2% RSD |
| Data System Compliance | FDA 21 CFR Part 11, GLP/GMP-ready |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | ACQUITY UPLC I-Class PLUS |
| Instrument Type | Ultra-Performance Liquid Chromatograph (UPLC) |
| Maximum Pressure | 18,000 psi |
| Temperature Control Range | 4–90 °C |
| Injection Volume Range | 0.1–1000 µL |
| Detector Compatibility | Low-diffusion UV/Vis, PDA, and MS-coupled configurations |
| Column Management | Active pre-heating, dual-column switching, optional 2D-LC valve |
| Software Support | Waters Empower, MassLynx, UNIFI, and third-party LC-MS platforms |
| Compliance | Designed for GMP/GLP, ISO/IEC 17025, USP <1058>, FDA 21 CFR Part 11 audit trail readiness |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | ACQUITY UPLC |
| Instrument Type | Comprehensive Two-Dimensional Liquid Chromatography (2D-LC) System |
| Configuration | Modular, valve-driven, pump-synchronized dual-gradient platform |
| Software Integration | Empower 3 / UNIFI with dedicated 2D-LC method templates |
| Compliance Framework | Designed for GLP/GMP environments |
| Column Compatibility | Fully compatible with sub-2-µm particle UPLC columns (e.g., BEH, CSH, HSS series) |
| System Architecture | Dual binary solvent manager (BSM) or quaternary solvent manager (QSM) configurations with high-pressure switching valves (e.g., 10-port/2-position, 6-port/2-position) |
| Flow Rate Range | 0.001–2.000 mL/min (per dimension, programmable independently) |
| Maximum System Pressure | 15,000 psi (103 MPa) |
| Injection Volume Range | 0.1–100 µL (with precision loop or needle-wash-enabled autosampler) |
| Column Oven Temperature Range | 4–90 °C (±0.1 °C stability) |
| UV/Vis Detection Wavelength Range | 190–800 nm (with TUV or PDA detectors) |
| Data Acquisition Rate | Up to 100 Hz (for high-resolution 2D contour plot generation) |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | ACQUITY UPLC I-Class |
| Instrument Type | Ultra-High-Performance Liquid Chromatograph (UHPLC) |
| Sample Introduction | Low-Diffusion, Dual-Needle, Independent Autosampler |
| Pressure Range | Up to 130 MPa (1300 bar) |
| Flow Rate Range | 0.001–2.0 mL/min |
| Column Temperature Control | 5–100 °C |
| UV/Vis Detection Wavelength Range | 190–800 nm |
| Data Acquisition Rate | Up to 100 Hz |
| Compliance | Fully Compatible with FDA 21 CFR Part 11, ASTM D7416, USP <621>, ISO/IEC 17025 |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | e2695 |
| Instrument Type | Conventional High-Performance Liquid Chromatograph |
| Sample Capacity | Up to 120 vials (standard 12 × 75 mm or 18 × 150 mm) |
| Flow Rate Range | 0.05–50 mL/min |
| Maximum Pressure | 20 MPa (2900 psi) |
| Injection Volume | 0.1–100 µL (programmable, no loop change required) |
| Column Oven Temperature Range | Ambient +5 °C to 60 °C |
| UV-Vis Detection Wavelength Range | 190–700 nm (when paired with 2489/2487/2998 detectors) |
| Data Acquisition Rate | Up to 80 Hz (detector-dependent) |
| Compliance | Designed for GLP/GMP environments |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | ACQUITY Premier System |
| Instrument Type | Ultra-High Performance Liquid Chromatograph (UHPLC) |
| Application Scope | General-purpose analytical chromatography |
| Core Technology | MaxPeak High-Performance Surface (HPS) |
| Software Compatibility | Empower, MassLynx, UNIFI |
| Regulatory Alignment | Designed for GLP/GMP environments with audit trail and electronic signature support per FDA 21 CFR Part 11 |
| Brand | Waters |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported Instrument |
| Model | ACQUITY Arc |
| Instrument Type | Ultra-High Performance Liquid Chromatograph (UHPLC) |
| Solvent Delivery | Quaternary Gradient System |
| Column Compatibility | 2.0–5.0 µm particles |
| System Dispersion | Optimized for Low Extra-Column Band Broadening |
| Detection Compatibility | Fully Integrated with ACQUITY QDa Mass Detector |
| Software Platform | Empower 3 and MassLynx |
| Regulatory Compliance | Supports 21 CFR Part 11, GLP/GMP, ISO/IEC 17025, USP <1058> |
| Auto-Blend Plus | Enabled |
| Needle Wash FTN Mode | Cross-Contamination < 0.002% |
| Column Oven Options | Integrated Pre-heating & Active Heating/Cooling |
| Multi-Flow Path Architecture | Dual Path (Path 1: HPLC-optimized |
| Path 2 | UHPLC-optimized) |
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