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| Brand | Waters |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | AutoPurification |
| Application Level | Laboratory Grade |
| Instrument Type | High-Pressure Preparative Liquid Chromatography |
| UV/Vis Detection | Standard Configurable |
| MS Compatibility | Native HPLC/MS Integration |
| Fraction Collection | Automated, Signal-Triggered (UV, ELSD, MS, Analog) |
| Software Platform | FractionLynx™ |
| Column Technology | Optimized Bed Density (OBD) Columns |
| Scalability | Analytical-to-Preparative Upgrade Path |
| Automation Capability | Unattended Operation |
| Sample Throughput | Multi-hundred-sample Batch Processing |
| Loading Capacity | Milligram-to-Gram Scale Purification |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Prep 150 |
| Application Level | Laboratory-grade |
| Instrument Type | High-pressure preparative LC |
| Pump Configuration | Binary or Quaternary (low-pressure solvent selection or high-pressure gradient mixing up to 150 mL/min) |
| Detector Options | 2489 UV/Vis or 2998 Photodiode Array (PDA) |
| Column Compatibility | Up to 50 mm internal diameter |
| Sample Load Range | Milligram- to gram-scale purification |
| Software | ChromScope™ for method development, fraction simulation, and GLP-compliant data handling |
| Compliance | Designed to support 21 CFR Part 11–ready workflows with audit trail and electronic signature capability (when configured with appropriate IT infrastructure) |
| Brand | Waters |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported Instrument |
| Model | Analytical to Semi-Preparative HPLC Purification |
| Application Level | Laboratory Grade |
| Instrument Type | Medium-to-Low Pressure Preparative Liquid Chromatography |
| Flow Rate Capability | Up to 300 mL/min |
| Detection Options | UV-Vis PDA, ELSD, or Analog-Signal-Compatible Detectors |
| Fraction Collection | Waters Fraction Collector III |
| Column Technology | Optimized Bed Density (OBD) Columns |
| Software Platform | Empower Chromatography Data System (CDS) |
| Compliance Support | 21 CFR Part 11 Ready, GLP/GMP-Aware Workflow Design |
| Sample Load Range | Microgram-to-Milligram Scale |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Investigator SFC System |
| Application Level | Laboratory Grade |
| Instrument Type | Semi-Preparative Supercritical Fluid Chromatography System |
| Flow Rate Range | Up to 15 mL/min |
| Column Capacity | Up to 10 analytical columns or 6 preparative columns |
| Integrated Autosampler | Waters Alias |
| Software Platform | SuperChrom |
| Optional Detectors | 2998 Photodiode Array (PDA) Detector, 2424 Evaporative Light Scattering (ELS) Detector |
| Dimensions (H×L×W) | 92 cm × 98 cm × 68 cm |
| Regulatory Compliance | Designed for GLP/GMP-aligned workflows |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Prep 100q SFC |
| Application Level | Laboratory Grade |
| Instrument Type | High-Pressure Preparative SFC System |
| Flow Rate Range | Up to 100 mL/min |
| Mobile Phase | CO₂-based supercritical fluid (co-solvent compatible) |
| Fraction Collection | Automated open-loop collection with UV- or MS-triggered modes |
| Compliance | Designed for GLP/GMP-aligned workflows |
| Separation Mode | Chiral and achiral preparative separations |
| Sample Scale | Milligram- to gram-scale purification |
| Brand | Waters |
|---|---|
| Origin | USA |
| Instrument Type | Preparative Supercritical Fluid Chromatography (SFC) System |
| Model Variants | 80, 200, 350 |
| Application Level | Laboratory-Scale Purification |
| Regulatory Context | Designed for GLP-compliant workflows and compatible with FDA 21 CFR Part 11–enabled software environments |
| Compliance Framework | Supports ASTM D7894–21 (Standard Guide for SFC Method Development), ISO 17025–2017 (Testing Laboratory Competence), and USP <621> Chromatography guidelines |
| Software Platform | SuperChrom v3.x (with audit trail, electronic signatures, and method versioning) |
| Detection | UV-Vis absorbance detection (dual-wavelength capability) |
| Fraction Collection | Automated, timed or peak-triggered, with solvent compatibility up to 100% CO₂-expanded liquids and polar modifiers (e.g., methanol, ethanol, isopropanol) |
| Back Pressure Control | Active Automatic Back Pressure Regulator (ABPR) with ±0.2 bar pressure stability |
| Solvent Delivery | Dual-pump architecture — primary CO₂ pump (supercritical phase delivery) and auxiliary modifier pump (liquid-phase co-solvent gradient) |
| System Architecture | Modular, rack-mounted configuration with integrated safety interlocks, CO₂ phase monitoring, and real-time density compensation |
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