BOXUN BXM-110VE Vertical Steam Autoclave
| Brand | BOXUN |
|---|---|
| Origin | Shanghai, China |
| Model | BXM-110VE |
| Instrument Type | Vertical Autoclave |
| Max Temperature | 150 °C |
| Max Pressure | 0.38 MPa |
| Chamber Dimensions | Ø400 × 835 mm |
| External Dimensions | 535 × 640 × 1275 mm |
| Chamber Volume | 110 L |
| Temperature Uniformity | ±0.5 °C |
| Temperature Fluctuation | < +1 °C |
| Sterilization Temp Range | 105–135 °C |
| Melting Temp Range | 50–100 °C |
| Holding Temp Range | 40–60 °C |
| Sterilization Time Range | 0–120 min (customizable up to 6000 min) |
| Melting/Holding Time Range | 0–6000 min |
| 预约 Function | Up to 100 h |
| Heating Power | 3.5 kW |
| Power Supply | ~220 V ± 22 V, 50 Hz ± 1 Hz |
| Operating Ambient | 5–40 °C, 20–80% RH |
| Cooling System | Standard air-cooling + secondary water-cooling + condenser |
| Safety Protections | Overtemperature shutdown, low-water cutoff, overpressure mechanical relief, independent electronic overpressure sensor, anti-scald insulation, overload protection, short-circuit protection, earth leakage protection |
| User Access Levels | Engineer / Administrator / Operator (3-tier permission management) |
| Interface | Capacitive touchscreen, RS-485 ×2, G1/2A calibration port, waterproof socket ×1 |
Overview
The BOXUN BXM-110VE Vertical Steam Autoclave is an ISO-compliant, Class B-capable gravity displacement and pre-vacuum compatible sterilization system engineered for routine and validation-critical applications in academic laboratories, clinical diagnostics, pharmaceutical QC labs, and biotechnology facilities. It operates on the principle of saturated steam under controlled pressure and temperature to achieve microbial inactivation through protein denaturation and nucleic acid disruption. Designed to meet the fundamental requirements of EN 13060:2014 and align with key elements of ISO 17665-1 for moist heat sterilization, the BXM-110VE delivers reproducible lethality (F0) across its 110 L chamber volume. Its dual-mode capability—supporting both gravity-based air removal and programmable positive-pressure pulse evacuation—ensures consistent steam penetration into porous loads, wrapped instruments, and fluid-filled containers. The system’s calibrated temperature control (±0.5 °C uniformity, < +1 °C fluctuation) and traceable pressure regulation (0.22 MPa working, 0.38 MPa design limit) enable compliance with USP , EP 5.1.1, and FDA 21 CFR Part 11 when integrated with validated software and audit-trail-enabled peripherals.
Key Features
- PMMA-I microprocessor control system with 7-inch capacitive touchscreen interface, supporting real-time visualization of temperature, pressure, time, phase status, and dynamic process graphs
- Eight factory-preset sterilization programs plus six user-definable protocols, each configurable for temperature setpoint, dwell time, vacuum level, pulse count, and exhaust rate
- Six-stage positive-pressure pulse air removal with adjustable cycle depth—optimized for complete cold-air evacuation from hollow devices and multi-layered packs
- Six-level programmable post-cycle depressurization to minimize thermal shock and condensation in sensitive media loads
- Triple-layer cooling architecture: integrated condenser, forced-air convection, and secondary water-cooling circuit—reducing chamber cooldown time by up to 40% versus conventional air-only systems
- Three-tier access control (Operator / Administrator / Engineer) with password-protected parameter modification, program editing, and service diagnostics
- Comprehensive safety redundancy: dual overtemperature sensors, independent electronic overpressure cutoff, mechanical pressure relief valve, automatic water-level monitoring, earth leakage detection, and thermal-insulated outer casing rated to <45 °C surface temperature during operation
- 100-hour delayed start scheduling and adjustable boiling point compensation—enabling reliable operation at altitudes up to 3,000 m above sea level
Sample Compatibility & Compliance
The BXM-110VE accommodates a broad spectrum of load types including liquid media (e.g., agar, broth), solid instruments (stainless steel, aluminum), glassware (flasks, pipettes), polymer containers (polypropylene, polycarbonate), and regulated biohazard waste bags. Its Ø400 × 835 mm cylindrical chamber supports standard sterilization trays (370 × 245 mm) stacked three high, while the G1/2A calibration port and optional validation seal adapters allow integration of wired PT100 or thermocouple probes per ISO 17665-2 Annex C. The system meets CE marking requirements for medical device sterilizers (MDR 2017/745), conforms to GB 8599–2008 (Chinese national standard for autoclaves), and provides foundational infrastructure for GLP/GMP environments requiring documented sterilization cycles, F0 calculation, and electronic record retention.
Software & Data Management
Data integrity is maintained via dual RS-485 serial interfaces supporting Modbus RTU protocol for integration with LIMS or SCADA platforms. Optional thermal printer (SPR-300 series, Chinese-manufactured thermal unit) provides timestamped hardcopy output of cycle parameters, real-time temperature/pressure curves, and F0 values when paired with a calibrated sample probe. All cycle logs—including start/stop timestamps, operator ID, program name, deviation alerts, and safety interlock events—are stored internally with USB export capability (U-disk included). When deployed with validated third-party software, the system supports 21 CFR Part 11-compliant electronic signatures, audit trails, and role-based data access controls required for regulated pharmaceutical manufacturing.
Applications
- Routine sterilization of microbiological growth media, buffers, and reagents in teaching and research laboratories
- Preparation of sterile surgical kits, dental handpieces, and reusable labware in hospital central sterile supply departments (CSSD)
- Validation-grade processing of reference standards, calibration materials, and QC samples in pharmaceutical quality control labs
- Decontamination of infectious waste in biosafety level 2 (BSL-2) containment facilities
- Thermal processing of tissue culture flasks, bioreactor components, and filtration housings in cell therapy workflows
- High-altitude field deployment where ambient pressure variations affect steam saturation behavior
FAQ
What sterilization standards does the BXM-110VE comply with?
It meets EN 13060:2014 for small steam sterilizers, GB 8599–2008, and incorporates functional requirements aligned with ISO 17665-1 for validation of moist heat processes.
Can the BXM-110VE perform vacuum-assisted cycles?
Yes—it supports positive-pressure pulse air removal (not full vacuum), enabling effective steam penetration for wrapped and porous loads without requiring a dedicated vacuum pump.
Is F0 calculation available?
F0 is calculated and printable when used with an optional calibrated sample temperature probe and the thermal printer module.
What is the maximum altitude rating for reliable operation?
The boiling point adjustment function ensures accurate temperature control up to 3,000 meters elevation.
Are validation accessories included as standard?
The G1/2A calibration port and chamber-mounted reference sensor are standard; validation seal adapters and probe cables are optional.
Does the system support remote monitoring or network connectivity?
Native Ethernet is not provided, but RS-485 Modbus RTU enables integration into facility-wide monitoring systems via gateway hardware.
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