Xiangyi H2100R Benchtop High-Speed Refrigerated Centrifuge

Overview

The Xiangyi H2100R Benchtop High-Speed Refrigerated Centrifuge is an engineered solution for laboratories requiring high-throughput, temperature-controlled separation of biological macromolecules, cell suspensions, and clinical specimens. Utilizing a brushless AC frequency-converter motor coupled with a high-efficiency eco-friendly refrigeration system, the H2100R delivers stable rotational performance across its full operational range (200–21,000 rpm), achieving a maximum relative centrifugal force (RCF) of 30,642 × g. Its horizontal rotor configuration supports up to four 750 mL bottles—enabling scalable processing of large-volume samples without compromising thermal stability or mechanical integrity. The instrument operates within a precisely regulated temperature range of –20 °C to +40 °C, maintaining sample integrity during prolonged runs typical in nucleic acid purification, plasma fractionation, and microbial pellet recovery.

Key Features

• Microprocessor-based control architecture with full-touch LCD interface for intuitive parameter entry, real-time status monitoring, and graphical run visualization.
• Automatic rotor recognition system ensures compliance with maximum speed limits per rotor type—preventing mechanical over-speed conditions through hardware-enforced firmware validation.
• Electronically actuated door lock with interlock verification provides physical and logical safety redundancy; door cannot open during rotation or until deceleration reaches safe thresholds.
• Comprehensive safety suite includes dynamic imbalance detection, real-time temperature deviation alerting, overspeed cutoff, and continuous rotor health assessment via load-sensing feedback.
• Programmable acceleration and deceleration profiles (10 ramp-up and 11 ramp-down curves) minimize shear-induced resuspension and optimize sediment compaction—critical for sensitive applications such as ribosome isolation or exosome pelleting.
• Dual setpoint mode allows direct input of either rotational speed (rpm) or RCF (× g), supporting both method-driven and physics-driven experimental design conventions.

Sample Compatibility & Compliance

The H2100R accommodates standard clinical and research formats including conical tubes (15–50 mL), blood collection tubes (e.g., EDTA, heparin), and large-volume centrifuge bottles (up to 750 mL). Its horizontal rotor design supports swing-out configurations ideal for density gradient separations (e.g., Ficoll-Paque™, Percoll®) and low-sedimentation-rate applications. The system is constructed using corrosion-resistant stainless-steel chambers and sealed refrigerant circuits compliant with international environmental standards (RoHS, REACH). While not certified under FDA 21 CFR Part 11 out-of-the-box, the H2100R’s firmware architecture permits integration into validated laboratory information management systems (LIMS) with electronic signature and audit trail capabilities—supporting GLP and GMP-aligned workflows where documented traceability is required.

Software & Data Management

All operational parameters—including time, speed, temperature, RCF, and rotor ID—are logged automatically per run and stored in non-volatile memory. The onboard system retains up to 99 user-defined protocols, each editable with descriptive naming, step sequencing, and conditional logic for multi-phase cycles (e.g., pre-cool → accelerate → hold → decelerate → post-hold). Data export is supported via USB port in CSV format for downstream analysis in Excel or statistical software packages. Optional Ethernet connectivity enables remote diagnostics and centralized fleet monitoring in core facility settings.

Applications

• Molecular biology: Plasmid DNA purification, viral vector concentration, RNA extraction from tissue homogenates.
• Clinical diagnostics: Serum/plasma separation from whole blood, PBMC isolation, urinary sediment analysis.
• Cell culture: Harvesting adherent and suspension cells, clarifying conditioned media, concentrating extracellular vesicles.
• Biopharmaceutical QC: Clarification of fermentation broths, removal of host-cell proteins, buffer exchange prior to chromatography.
• Virology & immunology: Purification of lentiviral particles, influenza HA antigen preparation, immune complex precipitation.

FAQ

What is the minimum and maximum operating temperature?
The refrigeration system maintains chamber temperatures between –20 °C and +40 °C, with ±1.5 °C accuracy at setpoint.
Does the H2100R support rotor calibration certificates?
Yes—each rotor is supplied with a factory-verified calibration report referencing ISO 15197 and ASTM E2917 standards for angular velocity and RCF traceability.
Can I use third-party rotors with this centrifuge?
No—the automatic rotor recognition system only accepts Xiangyi-certified rotors equipped with proprietary identification encoding; unauthorized rotors will not initialize.
Is the H2100R suitable for continuous operation in a 24/7 core facility?
Yes—its industrial-grade compressor, dual-stage cooling circuit, and thermal overload protection enable uninterrupted duty cycles up to 8 hours at 18,000 rpm and –10 °C.
How is data integrity ensured during power interruption?
The unit features a supercapacitor-backed memory module that preserves active protocol state and recent run logs for up to 72 hours without external power.