YiHeng BPH-9042 / BPH-9082 / BPH-9162 / BPH-9272 Precision Temperature-Controlled Incubator
| Brand | YiHeng |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Models | BPH-9042, BPH-9082, BPH-9162, BPH-9272 |
| Price Range | USD 750–1,850 (FOB) |
| Temperature Range | RT + 5°C to 80°C |
| Temperature Uniformity | ±1.5°C |
| Humidity Control | Not Available |
| Chamber Capacity | 42 L to 408 L |
Overview
The YiHeng BPH series precision temperature-controlled incubators are engineered for stable, reproducible thermal environments in cell culture, microbiological growth, enzyme assays, and long-term stability studies. These forced-air incubators operate on a convection-based thermal regulation principle—employing an optimized air circulation system with adjustable fan speed control—to minimize thermal gradients and ensure uniform heat distribution across the entire chamber volume. Designed for routine laboratory use under ISO 13485-aligned manufacturing practices, the BPH series complies with general safety requirements per IEC 61010-1 and supports GLP-compliant workflows through programmable operation, audit-ready event logging (when equipped with optional data interfaces), and dual-stage temperature protection architecture.
Key Features
- Intuitive LCD interface with multi-parameter real-time display (setpoint, actual temperature, elapsed time, remaining time, fan status) and menu-driven navigation for rapid setup and monitoring;
- Mirror-finish stainless-steel interior with seamless quarter-radius corners and removable, height-adjustable shelving—facilitating thorough cleaning and reducing microbial retention points;
- Intelligent variable-speed fan control: automatically modulates airflow velocity during steady-state operation to maintain optimal laminar conditions for sensitive biological samples while minimizing evaporative loss;
- Fuzzy PID temperature controller with ±0.1°C setpoint resolution, <0.3°C typical temperature fluctuation at setpoint, and programmable ramp/soak profiles;
- Independent overtemperature cut-off circuit with audible/visual alarm—mechanically isolated from the main control system to meet functional safety requirements for unattended operation;
- 7-segment, 63-step programmable controller supporting complex thermal protocols: simultaneous scheduling of temperature, fan speed, dwell time, ramp rate, and power state (auto-start, standby, shutdown);
- Dedicated 25 mm diameter access port on right-side chamber wall for sensor cabling, gas tubing, or external monitoring without compromising seal integrity.
Sample Compatibility & Compliance
The BPH series accommodates standard-sized cell culture flasks (T25–T225), Petri dishes (up to 150 mm), multi-well plates (6–96-well), and microbiological tubes. Its non-humidified chamber design is suitable for applications where moisture management is externally controlled (e.g., CO2 incubator pre-conditioning, dry-heat sterilization validation, or thermotolerance assays). The equipment meets CE marking requirements for laboratory electrical safety and electromagnetic compatibility (EMC Directive 2014/30/EU). While not certified for IVD or medical device use, its construction and performance align with ASTM E1249–22 (Standard Practice for Performance Testing of Forced-Air Laboratory Incubators) and supports internal validation per USP environmental monitoring protocols when integrated into cleanroom-adjacent workflows.
Software & Data Management
Standard configuration includes built-in time-stamped event logging (power-on/off, alarm triggers, setpoint changes). Optional RS-485 Modbus RTU or USB host interface enables integration with LabVantage, STARLIMS, or custom SCADA systems. When connected to a USB flash drive (FAT32 formatted), the incubator records timestamped temperature data at user-defined intervals (1–60 min) for up to 30 days—providing raw CSV output compatible with Excel, Python pandas, or JMP for statistical process control (SPC) analysis. All data exports include firmware version, serial number, and UTC timestamps to support FDA 21 CFR Part 11 compliance when deployed with validated electronic signature and audit trail software layers.
Applications
- Mammalian and insect cell line propagation under defined thermal conditions;
- Bacterial and fungal colony development for AST (antibiotic susceptibility testing) and bioburden assessment;
- Enzyme kinetics studies requiring precise isothermal incubation (e.g., restriction digests, ligations, ELISA plate incubation);
- Accelerated stability testing of pharmaceutical intermediates and excipients per ICH Q1A(R2);
- Pre-incubation of samples prior to downstream analytical steps (e.g., HPLC sample prep, PCR master mix equilibration);
- Environmental simulation for material aging tests (e.g., polymer degradation, adhesive curing).
FAQ
Does this incubator support humidity control?
No. The BPH series is a dry-air, temperature-only incubator. For humidified applications, consider YiHeng’s BH series CO2 incubators or external humidification modules.
What is the maximum allowable ambient temperature for continuous operation?
The unit is rated for ambient temperatures between 10°C and 30°C. Operation above 30°C may compromise temperature uniformity and shorten compressor service life.
Can the incubator be validated for GMP environments?
Yes—the design supports IQ/OQ/PQ execution. Required documentation (DQ templates, calibration certificates, FAT/SAT reports) is available upon request for qualified purchasers.
Is the programming logic compliant with 21 CFR Part 11?
The hardware supports Part 11 readiness; full compliance requires implementation of third-party electronic signature and audit trail software layered atop the native data export functionality.
What maintenance is recommended for long-term reliability?
Quarterly inspection of air filter (if installed), annual verification of temperature sensor calibration against NIST-traceable reference, and biannual cleaning of condenser coils using compressed air or soft brush.
