YIHENG HZQ Series Large-Capacity Incubator Shaker with LCD Display

Overview

The YIHENG HZQ Series Large-Capacity Incubator Shaker integrates precise temperature control and uniform orbital shaking in a single compact footprint—engineered for high-throughput cell culture, microbial fermentation, biochemical assays, and suspension-based bioprocessing. Unlike conventional shakers or standalone incubators, this air-jacketed system employs forced-air convection combined with a triple-eccentric shaft drive mechanism to deliver exceptional thermal homogeneity (±0.3°C at 37°C) and mechanical stability across the full speed range (40–300 rpm). Its dual-shelf architecture supports simultaneous operation of two independent sample zones—each with identical thermal and kinetic profiles—making it suitable for comparative studies, parallel process optimization, or staggered inoculation protocols under controlled environmental conditions.

Key Features

• Triple-eccentric shaft balanced drive system ensures consistent orbital motion across the entire platform surface—even at maximum load (up to 20 kg per shelf) and 300 rpm—with minimal vibration transmission to adjacent equipment.
• Microprocessor-based PID control for both temperature and speed, with real-time feedback loops ensuring ±1 rpm speed accuracy and ±0.3°C temperature stability over time.
• Large-format backlit LCD interface with intuitive menu navigation, supporting multi-language display (English default), parameter lockout, and on-screen diagnostic codes for rapid troubleshooting.
• Double-glazed, tempered observation window with low-emissivity coating provides optical clarity during operation while minimizing heat loss—critical for energy-efficient long-term incubation.
• Interior chamber, platform surfaces, and shelves constructed entirely from electropolished 304 stainless steel for corrosion resistance, autoclavable compatibility, and compliance with GLP cleaning validation requirements.
• 25 mm external access port (left-side mounted) enables sterile tubing, sensor cabling, or gas line integration without compromising chamber integrity.
• Intelligent safety architecture includes automatic shutdown upon door opening, independent over-temperature cut-off (adjustable limit), stall-detection for motor protection, and programmable ramp-to-setpoint to prevent thermal shock to sensitive cultures.

Sample Compatibility & Compliance

The HZQ Series accommodates standard laboratory vessels including Erlenmeyer flasks (50–5000 mL), baffled flasks, deep-well microplates, and custom bioreactor bags via interchangeable clamps and universal platform inserts. Its airflow design meets ISO 14644-1 Class 8 cleanroom-compatible ventilation standards when operated in controlled environments. The unit complies with IEC 61010-1:2010 for electrical safety and is CE-marked for use within the European Economic Area. Optional configurations support USP analytical instrument qualification (AIQ) documentation packages and FDA 21 CFR Part 11–compliant audit trails when paired with YIHENG’s validated data logging software.

Software & Data Management

Equipped with RS-485 serial interface and USB host port (U-disk compatible), the shaker supports direct connection to Windows-based PCs running YIHENG DataMaster™ v3.2 software. This application enables real-time monitoring of temperature, speed, elapsed time, and alarm status; scheduled data export in CSV/Excel format; and graphical trend visualization with timestamped event markers. For regulated environments, optional firmware upgrade enables electronic signature capture, user-level permission tiers, and immutable record storage meeting ALCOA+ principles. Printer output (via USB or RS-232) generates hard-copy logs compliant with ISO/IEC 17025 documentation requirements.

Applications

• Mammalian and insect cell suspension culture (CHO, HEK293, Sf9) under controlled O₂/CO₂ environments (when integrated with external gas mixing modules).
• High-yield recombinant protein expression in E. coli and Pichia pastoris, where precise temperature ramping and agitation synchronization improve plasmid stability and induction efficiency.
• Enzyme kinetics assays requiring stable thermal conditions and homogeneous mixing across multi-well plate formats.
• Environmental microbiology studies involving soil slurry respiration, wastewater biomass propagation, or biofilm disruption analysis.
• Stability testing of biopharmaceutical intermediates per ICH Q5C guidelines, leveraging its extended runtime capability (>30 days continuous operation verified at 150 rpm, 37°C).

FAQ

Does the HZQ Series support 4°C refrigerated operation?
Yes—models equipped with enhanced low-temperature compressors and upgraded insulation achieve stable 4°C operation with ±0.5°C uniformity across the chamber.
Can the dual shelves operate at different temperatures or speeds?
No—the system maintains identical setpoints across both shelves to ensure experimental reproducibility; independent control requires two separate units.
Is the unit suitable for GMP manufacturing environments?
With optional IQ/OQ documentation, 21 CFR Part 11 software module, and stainless-steel fluid path certification, it meets baseline requirements for ancillary equipment in non-sterile API manufacturing.
What maintenance is required for the DC motor drive?
The brushless DC motor is sealed and maintenance-free; only periodic inspection of fan filters and calibration verification every 12 months are recommended.
How is temperature uniformity validated across the working volume?
YIHENG provides a 9-point mapping report per unit (per ASTM E145-22 Annex A3), traceable to NIST-certified thermistors, included in shipment documentation.