New Brunswick Innova 40 R Refrigerated Benchtop Incubated Shaker

Overview

The New Brunswick Innova 40 R is a precision-engineered refrigerated benchtop incubated shaker designed for demanding life science applications requiring simultaneous temperature control, orbital agitation, and long-term operational stability. Utilizing a robust three-eccentric-shaft drive system mounted on a cast-iron base, the Innova 40 R delivers vibration-damped, low-noise orbital motion across its full speed range (25–500 rpm), minimizing mechanical stress on sensitive biological cultures and ensuring high reproducibility in aerobic microbial growth, protein expression, cell suspension maintenance, and enzymatic reaction kinetics. Unlike non-refrigerated counterparts, the Innova 40 R integrates an active cooling module that enables sub-ambient temperature operation—critical for thermolabile sample handling, cold-adapted organism cultivation, or protocols requiring precise thermal ramping without external chillers. Its compact footprint (W × D × H: 66 × 71 × 53 cm) allows seamless integration into biosafety cabinets, cold rooms, or standard laboratory benches while accommodating up to three 3-L Erlenmeyer flasks on a single 46 × 46 cm stainless-steel platform.

Key Features

• Cast-iron base with three-eccentric-shaft balanced drive architecture—engineered for high-load stability and minimal transmission of mechanical resonance to adjacent instrumentation.
• Refrigeration-enabled temperature control spanning 15°C below ambient to 80°C, with independent heating/cooling circuits ensuring rapid thermal equilibration and ±0.3°C uniformity across the platform (per ISO 13732-1 at steady state).
• Low-noise operation (<55 dBA at 300 rpm), achieved via optimized motor isolation and gearless direct-drive transmission—suitable for shared lab environments and continuous unattended runs.
• Transparent polycarbonate lid with quick-release latch enables real-time visual monitoring without interrupting temperature or agitation conditions; lid interlock prevents operation when open.
• Modular platform compatibility: accepts optional universal clamps, flask holders (for 125 mL–3 L vessels), microplate adapters (96-/384-well), and tube racks—all secured via standardized M6 threaded inserts.
• Compliance-ready design: certified to cETLus (UL 61010-1), CSA C22.2 No. 61010-1, and CE (2014/30/EU EMC & 2014/35/EU LVD directives), supporting auditability under GLP and ISO/IEC 17025-accredited workflows.

Sample Compatibility & Compliance

The Innova 40 R supports heterogeneous sample formats including glass and PETG Erlenmeyer flasks (up to 3 L), borosilicate test tubes (10–50 mL), deep-well microplates, and custom bioreactor vessels fitted with compatible mounting hardware. Its orbital motion profile (190 mm or 250 mm diameter selectable per configuration) ensures homogeneous mixing across viscous media (e.g., glycerol-rich LB broth or methylcellulose-based stem cell suspensions) without vortex formation or shear-induced cell lysis. Temperature uniformity is validated per ASTM E2500-13 Annex A3 for incubator shakers, with traceable calibration options available via factory-certified NIST-traceable probes. The unit meets essential requirements for FDA 21 CFR Part 11-compliant environments when paired with New Brunswick’s optional data-logging software (see Software & Data Management section).

Software & Data Management

While the Innova 40 R operates via intuitive front-panel controls (rotary encoder + LCD display), it is fully compatible with New Brunswick’s optional “Eppendorf VisioNize Lab Suite” (v4.2+), enabling remote parameter setting, real-time graphing of temperature/speed profiles, and automated export of CSV-formatted logs with time-stamped metadata. Audit trails—including user ID, parameter changes, door-open events, and thermal deviation alerts—are stored locally and exportable for regulatory review. When deployed in GxP environments, the system supports electronic signatures, role-based access control, and 21 CFR Part 11-compliant electronic records when configured with validated firmware and network authentication protocols.

Applications

• Aerobic bacterial and yeast culture expansion under controlled O₂ transfer rates (via orbital speed and flask fill ratio optimization).
• Inducible protein expression in E. coli BL21(DE3) strains requiring precise 16–25°C induction temperatures.
• Mammalian suspension cell line maintenance (e.g., CHO-S, HEK293) with dissolved oxygen monitoring integration.
• Enzyme kinetics assays requiring stable sub-ambient temperatures (e.g., cold-active lipases at 10°C).
• Environmental microbiology studies involving psychrophilic isolates cultivated at 4–12°C with continuous agitation.
• Media preparation and solubilization of temperature-sensitive reagents (e.g., agarose, collagen, or antibody conjugates).

FAQ

Does the Innova 40 R support programmable temperature ramps?

Yes—when connected to VisioNize Lab Suite, users can define multi-step temperature/speed profiles with dwell times, linear ramps, and hold conditions.
Is the platform autoclavable?

No—the stainless-steel platform is chemically resistant and cleanable with 70% ethanol or 0.5% sodium hypochlorite, but is not rated for autoclave sterilization.
What is the maximum load capacity at 500 rpm?

The platform supports up to 25 kg distributed evenly; performance validation confirms ≤0.5 mm peak-to-peak displacement at full speed with 3 × 3-L flasks (water-filled).
Can the unit operate in a cold room at 4°C ambient?

Yes—the refrigeration system maintains setpoints as low as –11°C (15°C below 4°C ambient), provided ambient humidity remains below 80% RH and ventilation clearance is maintained.
Are calibration certificates included with shipment?

A factory-issued certificate of conformance is provided; NIST-traceable temperature and speed calibration certificates are available as optional add-ons (Order Code: CAL-INN40R-TC/SC).