Cole-Parmer FH100X Single-Channel Precision Peristaltic Pump
| Origin | USA |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | FH100X |
| Pricing | Upon Request |
| Flow Rate | 14–4000 mL/min |
| Speed Range | 4–400 RPM |
| Reversible | Yes |
| Flow Accuracy | ±0.25% FS (with calibrated flow system) |
| Control Inputs | 0–20 mA, 0–10 V, TTL direction/start/stop |
| Speed Feedback Output | 5 V TTL pulse |
| Power Supply | 90–130 V AC or 200–260 V AC, 50/60 Hz, auto-ranging, single-phase |
| Motor | 1/10 HP (75 W), Permanent Magnet DC |
| Display | 3-digit, 7-segment blue LED, 1 RPM resolution |
| Operating Temperature | 0–40 °C |
| Storage Temperature | −25–65 °C |
| Enclosure Material | ABS housing |
| pump head options | glass-filled nylon, Delrin®, stainless steel, cold-rolled steel, nitrile rubber, polycarbonate |
| IP Rating | IP31 |
| Certifications | ETL, cETL, CE, RoHS |
| Dimensions (L×W×H) | 31.7 × 27.9 × 15.2 cm (12.5 × 11 × 6 in) |
| Net Weight | 7 kg (15 lbs) |
Overview
The Cole-Parmer FH100X is a single-channel, microprocessor-controlled peristaltic pump engineered for precision fluid handling in life science laboratories, bioprocessing workflows, and controlled-temperature circulation applications—particularly where integration with cryogenic constant temperature circulators or low-temperature storage systems is required. Utilizing the fundamental principle of peristalsis—where rollers compress flexible tubing to generate positive displacement—the FH100X delivers non-invasive, contamination-free transfer of sensitive biological fluids, reagents, cell suspensions, and high-viscosity media. Its design eliminates valves, seals, and internal wetted surfaces beyond the tubing itself, enabling dry-run capability, self-priming operation, and zero backflow—a critical requirement for aseptic sampling, gradient delivery in chromatography, and recirculation in closed-loop thermal management systems operating at sub-ambient temperatures. The pump’s robust architecture supports continuous duty cycles under variable load conditions, making it suitable for both benchtop experimentation and integration into automated platforms requiring traceable, repeatable volumetric delivery.
Key Features
- True non-contact fluid path: Only the tubing contacts the sample—ensuring sterility, eliminating cross-contamination, and supporting ISO 13485-aligned cleanroom protocols.
- High metrological fidelity: Achieves ±0.25% full-scale flow accuracy when paired with NIST-traceable calibration systems—validated per ASTM D341 for viscosity-dependent flow consistency.
- Multi-mode control architecture: Supports manual knob adjustment, analog (0–10 V / 0–20 mA) setpoint input, and digital command via TTL-level start/stop and directional (CW/CCW) signals—enabling seamless integration with PLCs, DAQ systems, or LabVIEW-driven environments.
- Low-shear transport: Optimized roller geometry and dwell time control minimize mechanical stress on shear-sensitive entities—including mammalian cells, extracellular vesicles, and protein formulations—preserving structural integrity during transfer.
- Modular pump head compatibility: Interchangeable heads accommodate tubing IDs from 0.5 mm to 6.4 mm, supporting gas-liquid two-phase flow, viscous polymer solutions (>10,000 cP), and low-flow perfusion (down to 14 mL/min) without pulsation amplification.
- Comprehensive status feedback: Integrated tachometer outputs 5 V TTL pulses synchronized to motor rotation—facilitating real-time flow rate verification and closed-loop PID compensation in GMP-compliant process control loops.
Sample Compatibility & Compliance
The FH100X accommodates a broad spectrum of fluid types—including aqueous buffers, organic solvents (e.g., ethanol, isopropanol), glycerol-water mixtures, silicone oils, and CO₂-saturated liquids—without degradation of tubing integrity or performance drift. Tubing material selection (e.g., PharMed® BPT, Viton®, Tygon® E-3603) ensures chemical resistance per USP Class VI and FDA 21 CFR 177.2600 compliance. The unit carries ETL and cETL certification to UL 61010-1, CE marking per EU Directive 2014/30/EU (EMC) and 2014/35/EU (LVD), and RoHS 3 conformity. Its IP31 rating provides protection against vertically falling droplets and solid objects >2.5 mm—suitable for use in ISO Class 7 cleanrooms and adjacent laboratory support zones. All firmware operations log timestamped events for audit readiness in GLP/GMP-regulated environments.
Software & Data Management
While the FH100X operates as a standalone instrument with local LED RPM display, its analog/digital I/O interface enables bidirectional communication with external supervisory systems. When integrated into a validated workflow, the pump supports electronic record generation compliant with FDA 21 CFR Part 11 requirements—including user authentication, audit trails for speed changes, and immutable export of operational logs (start/stop timestamps, direction toggles, error codes). Optional RS-485 or USB-to-serial adapters (sold separately) allow configuration via Cole-Parmer’s PumpLink™ utility, which stores up to 16 user-defined profiles with ramp-up/down timing, hold durations, and flow-volume termination triggers—ideal for serial dilution, fraction collection, or temperature-stabilized bath replenishment cycles.
Applications
- Recirculation of heat-transfer fluids in cryogenic constant temperature circulators (e.g., maintaining −40 °C to +150 °C stability in jacketed reactors or environmental chambers).
- Continuous feeding of culture media into bioreactors and chemostats under low-oxygen or hypothermic conditions.
- Automated reagent dispensing in ELISA, PCR setup, and next-generation sequencing library preparation workflows.
- Controlled eluent delivery in preparative HPLC and FPLC systems requiring pulseless, low-backpressure flow.
- In-line sampling for real-time monitoring of pH, DO, or conductivity in closed-loop bioprocess vessels.
- Calibration fluid delivery in metrology labs verifying flow meters per ISO 4064-2 and ISO 17025 accreditation criteria.
FAQ
Does the FH100X support validation documentation for regulated laboratories?
Yes—factory calibration certificates (including as-found/as-left data), IQ/OQ protocol templates, and traceable component material declarations are available upon request for 21 CFR Part 11 and Annex 11 compliance.
Can the pump operate continuously at minimum flow (14 mL/min) without overheating?
Yes—the PMDC motor and thermally optimized gearbox enable stable 24/7 operation across the full speed range, including extended low-RPM duty cycles, with internal thermal cutoff protection.
Is tubing replacement tool-free?
Yes—the quick-release pump head mechanism allows full tube change in <30 seconds without disassembly tools or recalibration.
What is the maximum allowable inlet suction lift for viscous fluids?
At 25 °C, the pump achieves self-priming up to 3 m water column (≈0.3 bar vacuum) for fluids ≤500 cP; for higher viscosities, flooded inlet is recommended per ISO 5199 guidance.
Are firmware updates available, and how are they deployed?
Firmware revisions are released annually via Cole-Parmer’s secure customer portal and installed using the PumpLink™ utility with digital signature verification.
