Thermo Fisher TSP 100 & 200 Single-Channel HPLC Pumps (Refurbished, In Stock)

Overview

The Thermo Fisher TSP 100 and TSP 200 single-channel high-performance liquid chromatography (HPLC) pumps represent foundational components of the legacy Thermo Separation Products (TSP) platform—engineered for robust isocratic and gradient elution in analytical and preparative chromatographic workflows. These reciprocating piston pumps operate on dual-plunger technology with active solvent compressibility compensation, delivering stable flow rates across a wide range of mobile phase viscosities and backpressures (up to 5,000 psi). The TSP 100 is optimized for standard analytical applications requiring flow precision of ±0.1% RSD at 1 mL/min, while the TSP 200 extends capability with enhanced pressure tolerance and integrated pulse dampening for improved baseline stability in UV and electrochemical detection systems. Both units were originally manufactured in Thermo Fisher’s Canadian facility and conform to mechanical design standards aligned with IEC 61010-1 for laboratory equipment safety.

Key Features

• Factory-refurbished units with full functional validation—including leak testing, flow accuracy verification at 0.2, 1.0, and 3.0 mL/min, and pressure stability assessment under load
• Dual-piston architecture with ceramic-coated plungers and sapphire seals for extended service life and chemical resistance to common HPLC solvents (acetonitrile, methanol, aqueous buffers, THF)
• Onboard digital display and membrane keypad interface supporting manual flow/pressure setpoint entry and real-time status monitoring (e.g., “Standby”, “Run”, “Fault”)
• RS-232 serial interface for integration with legacy TSP autosamplers (e.g., SCM1000), column ovens (e.g., TSP 4000), and data systems including Chromeleon 6.x (via TSP driver suite)
• Modular front-panel design enabling field replacement of check valves, purge valves, and seal wash assemblies without specialized tools
• Compliance-ready documentation package provided upon request, including refurbishment log, test reports, and calibration traceability summary (NIST-traceable flow meters used during validation)

Sample Compatibility & Compliance

These refurbished TSP pumps are compatible with reversed-phase, normal-phase, ion-exchange, and size-exclusion chromatography columns ranging from 2.1 mm to 4.6 mm ID and lengths up to 250 mm. They support mobile phases containing volatile buffers (e.g., ammonium acetate, formic acid), non-volatile salts (e.g., sodium phosphate), and high-viscosity solvents (e.g., DMSO, ethylene glycol blends) within specified pressure limits. While not certified for current FDA 21 CFR Part 11 environments due to lack of electronic audit trail functionality, they are routinely deployed in GLP-compliant laboratories for method development, stability-indicating assays, and QC release testing where paper-based or CSV-log archiving satisfies regulatory expectations per ISO/IEC 17025:2017 Clause 7.7.

Software & Data Management

The TSP 100/200 pumps operate natively with Thermo’s legacy Chromeleon Chromatography Data System (CDS) versions 6.8 and earlier. Communication occurs via ASCII-based RS-232 protocol using standardized command sets (e.g., “FLOW=1.0”, “PRESSURE?”, “PURGE ON”). SpectraLab Scientific provides optional configuration assistance for integration into modern Windows 10/11 environments using USB-to-serial adapters and signed legacy drivers. All units ship with original firmware version 2.12 (TSP 100) or 3.04 (TSP 200); firmware upgrades are not supported beyond these versions per Thermo’s end-of-life policy (EOL notice issued Q4 2012). Raw diagnostic logs and system error history are accessible via terminal emulation software (e.g., PuTTY) for troubleshooting.

Applications

• Pharmaceutical impurity profiling per USP guidelines using C18 columns and UV detection at 210–280 nm
• Environmental analysis of PAHs and chlorinated pesticides in soil extracts per EPA Method 8330B
• Food safety testing for mycotoxins (aflatoxin B1, ochratoxin A) following AOAC Official Method 2005.03
• Polymer additive quantification (e.g., Irganox 1010, Tinuvin 770) in polyolefin matrices via GPC-compatible isocratic elution
• Academic teaching labs conducting fundamental HPLC theory instruction, including dwell volume measurement, gradient delay characterization, and dwell time correction exercises

FAQ

Are these units covered by Thermo Fisher’s original warranty?
No. As refurbished instruments sourced from decommissioned laboratory systems, they carry no manufacturer warranty. SpectraLab Scientific provides a 30-day limited technical support period for functional verification post-delivery.
Can the TSP 100/200 be integrated with modern Agilent or Waters CDS platforms?
Direct native integration is not supported. Interfacing requires third-party hardware abstraction layers (e.g., LabVIEW-based SCPI wrappers) or analog voltage output modules for flow/pressure mimicry—neither of which are supplied or validated by SpectraLab Scientific.
Is solvent compatibility documentation available?
Yes. A comprehensive chemical compatibility matrix covering >120 solvents and buffer systems—validated against TSP engineering bulletins TB-017 and TB-022—is included in the delivery package.
Do these pumps meet current ISO/IEC 17025 calibration requirements?
They comply with calibration interval recommendations outlined in ISO/IEC 17025:2017 Annex A.3.3 for secondary reference standards; however, formal accreditation must be performed by an ILAC-MRA signatory lab using traceable flow meters and pressure transducers.
What maintenance records accompany each unit?
Each pump ships with a refurbishment dossier containing date-stamped test reports, replaced component logs (seals, filters, valves), and a signed statement of conformance to SpectraLab’s internal Refurbishment Quality Protocol v4.2.