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PerkinElmer 200 Series High-Performance Liquid Chromatography System

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Origin Canada
Manufacturer Type Authorized Distributor
Origin Category Imported Instrument
Model 200
Price Range USD 13,500 – 40,500 (FOB)
Product Category Chromatography
Operational Age 4–5 years
Warranty 6 months limited parts and labor

Overview

The PerkinElmer 200 Series High-Performance Liquid Chromatography (HPLC) System is a robust, benchtop analytical platform engineered for precision separation, identification, and quantification of organic and inorganic compounds in complex matrices. Built upon proven dual-piston reciprocating pump architecture and UV/Vis detection with fixed-wavelength optics, the system operates on standard reversed-phase, normal-phase, and ion-exchange chromatographic principles. Designed for routine QC/QA laboratories, academic research facilities, and contract testing organizations, the 200 Series delivers high reproducibility in retention time (<0.1% RSD) and peak area (<0.5% RSD) under isocratic or gradient elution conditions. Its modular configuration supports integration with autosamplers, column ovens, and fraction collectors—enabling method scalability from development to validation. All units offered are fully refurbished by SpectraLab Scientific to original equipment manufacturer (OEM) functional specifications and verified against ASTM E260 and ISO 17025-aligned performance criteria.

Key Features

  • Stainless-steel dual-plunger reciprocating pump with pulse-dampening technology, delivering flow rates from 0.001 to 10.0 mL/min with ≤0.1% flow precision
  • Fixed-wavelength UV/Vis detector (typically 254 nm or 280 nm, configurable per unit), featuring 10 mm pathlength flow cell and <0.001 AU noise specification
  • Integrated solvent selection valve supporting up to four mobile phase reservoirs with low-dead-volume tubing paths
  • Front-panel keypad and LCD interface for standalone method setup; compatible with legacy PerkinElmer Turbochrom software via RS-232
  • Refurbishment includes full fluidic path cleaning, pump seal replacement, detector lamp calibration, and baseline stability verification over 60-minute runtime
  • Compliance-ready design: hardware and firmware support audit trail generation, user access levels, and electronic signature capability when paired with validated software environments

Sample Compatibility & Compliance

The PerkinElmer 200 Series accommodates standard 3.9–4.6 mm ID analytical columns (up to 250 mm length) and is routinely deployed for pharmaceutical impurity profiling, environmental pesticide residue analysis, food additive quantification, and polymer molecular weight distribution assessment. Each refurbished unit undergoes leak testing at 400 bar and pressure stability validation across its operational range (0–400 bar). Instruments conform to general safety requirements per IEC 61010-1 and electromagnetic compatibility standards EN 61326-1. While not supplied with pre-installed 21 CFR Part 11-compliant software, the system’s architecture supports integration into GxP-regulated workflows when operated with validated third-party chromatography data systems (CDS) that provide electronic records, audit trails, and role-based access control per FDA guidance.

Software & Data Management

The system operates natively with PerkinElmer Turbochrom CDS (versions 6.x–7.x), which provides sequence definition, real-time chromatogram display, peak integration, calibration curve generation, and report export in PDF, CSV, and XML formats. Refurbished units include licensed software media and activation keys where available; otherwise, users may deploy validated open-platform alternatives such as Chromeleon (Thermo Fisher) or Empower (Waters) via analog/digital signal interfaces. All instruments ship with complete digital documentation—including operation manuals, maintenance logs, and refurbishment certification—and support remote diagnostic assistance via TeamViewer-assisted troubleshooting. Raw data files (.chm, .raw) are fully compatible with third-party spectral libraries and chemometric tools for multivariate analysis.

Applications

  • Pharmaceutical quality control: assay of active pharmaceutical ingredients (APIs), related substances testing per USP & EP monographs
  • Environmental monitoring: determination of PAHs, PCBs, and chlorinated pesticides in soil and water extracts
  • Food and beverage safety: detection of mycotoxins (e.g., aflatoxin B1), preservatives (e.g., benzoic acid), and artificial colorants
  • Academic research: natural product isolation tracking, reaction mixture analysis, and polymer characterization via SEC/GPC mode
  • Industrial QC: raw material identity verification, cleaning validation swab extract analysis, and stability-indicating method execution

FAQ

Is this a factory-refurbished or dealer-refurbished instrument?
All PerkinElmer 200 Series systems are professionally refurbished by SpectraLab Scientific using OEM-specified procedures, including component-level testing, fluidic path decontamination, and full system performance qualification.
Does the 6-month warranty cover both parts and labor?
Yes—the warranty includes onsite or return-to-facility labor and all necessary replacement parts, excluding consumables (e.g., lamps, fuses, column filters).
Can the system be upgraded to support modern networking or compliance requirements?
While the base electronics do not support native Ethernet or USB connectivity, optional interface modules (e.g., RS-232 to TCP/IP converters) enable integration into modern LIMS environments. Full 21 CFR Part 11 compliance requires validated CDS software deployment.
Are column ovens or autosamplers included with the system?
These are available as optional accessories; configurations vary per unit. Detailed accessory inventories are provided upon request.
What documentation accompanies the instrument?
Each unit ships with a Certificate of Refurbishment, performance test report, electrical safety check record, and scanned copies of original OEM manuals—all traceable to the specific serial number.

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