Anton Paar Xsample Series Automated Sample Handler for Density Meters

Overview

The Anton Paar Xsample Series Automated Sample Handler is an engineered solution for high-precision, unattended density measurement of low-to-moderate viscosity liquids (≤1000 mPa·s) in laboratory environments. Integrated exclusively with Anton Paar’s DMA-series digital density meters—including DMA 4002, 5002, 6002, Lovis 2001, Sound Velocity Meters, Alcolyzer 7001, and Abbemat refractometers—the Xsample platform executes automated sample aspiration, transfer, cell filling, rinsing, and (in higher-tier models) drying. Its core operational principle relies on precise volumetric displacement via integrated peristaltic pumping and syringe-driven needle positioning, ensuring repeatable sample introduction into the U-tube oscillation cell without operator intervention. Unlike generic liquid handlers, the Xsample Series is purpose-built for density metrology: it maintains thermal equilibrium during transfer, minimizes air entrapment, and preserves the integrity of density-critical parameters such as temperature stability (±0.01 °C), vibration isolation, and bubble-free filling—key prerequisites for achieving ISO 12185- and ASTM D4052-compliant results.

Key Features

• Four modular configurations: Xsample 3100 (entry-level single-sample automation), Xsample 3200 (single-sample with internal/external needle cleaning), Xsample 5100 (multi-sample with barcode identification), and Xsample 5200 (flagship model with full rinse-dry cycles and highest throughput)
• Peristaltic pump integration ensures consistent, pulse-free liquid delivery; eliminates risk of syringe stalling or over-pressurization in viscous samples up to 1000 mPa·s
• Automated needle cleaning using up to three independent solvents (Xsample 3200/5100/5200), including inner-lumen and outer-surface flushing to prevent carryover and cross-contamination
• Optional 1D/2D barcode reader (Xsample 5100 & 5200) enables traceable sample identification, audit-ready log generation, and seamless LIMS integration
• Dedicated drying cycle (Xsample 5200 only) uses controlled airflow and temperature stabilization to remove residual solvent from the measuring cell prior to next analysis—critical for volatile or hygroscopic samples
• Intuitive SOP-based operation via Anton Paar’s One Click™ software interface; no programming required for routine workflows

Sample Compatibility & Compliance

The Xsample Series supports aqueous solutions, alcohols, hydrocarbons, organic solvents, beverages, pharmaceutical formulations, and chemical intermediates—with validated performance across densities from 0.6 g/cm³ to 3.0 g/cm³ and viscosities up to 1000 mPa·s. All models comply with IEC 61000-4 electromagnetic compatibility standards and meet CE marking requirements for laboratory instrumentation. When operated with DMA instruments running PATtools or LabX software, the system supports 21 CFR Part 11 compliance through electronic signatures, audit trails, user access levels, and immutable data archiving. Routine calibration verification is facilitated by built-in reference fluid handling protocols aligned with ISO/IEC 17025 quality management systems.

Software & Data Management

Xsample devices operate natively within Anton Paar’s LabX software environment—a secure, network-deployable platform supporting centralized method management, real-time instrument monitoring, and automated report generation. Each sample event logs timestamp, operator ID, instrument status, cleaning cycle execution, temperature history, and raw oscillation period data. Data export conforms to ASTM E1382 and ISO/IEC 17025 reporting templates, with optional CSV, PDF, or XML output. For regulated environments, LabX provides full electronic record retention, role-based permissions, and change control documentation—enabling full traceability from sample intake to certified result.

Applications

• Quality control laboratories in beverage, ethanol, and biofuel production requiring rapid, compliant alcohol content and density verification (e.g., EN 15376, OIML R 22)
• Pharmaceutical QC labs performing excipient density screening, syrup formulation checks, and USP density validation
• Chemical R&D facilities conducting polymer solution characterization, catalyst slurry density profiling, and solvent purity assessment
• Academic and contract testing labs executing multi-parameter campaigns combining density, sound velocity, and refractive index (via Abbemat coupling)
• Regulatory testing labs needing auditable, repeatable density workflows under GLP or GMP frameworks

FAQ

Which DMA instruments are compatible with Xsample 5200?
Xsample 5200 integrates with DMA 4002, 5002, 6002, Lovis 2001, Sound Velocity Meters, Alcolyzer 7001, and Abbemat high-performance and professional models.
Can Xsample handle viscous samples above 500 mPa·s reliably?
Yes—Xsample models support samples up to 1000 mPa·s when used with appropriate tubing, optimized flow rates, and pre-warmed sample conditioning; validation data available upon request.
Is drying functionality available on all Xsample models?
No—only Xsample 5200 includes a programmable drying step using thermally stabilized airflow; other models rely on solvent evaporation or manual drying.
How does Xsample ensure measurement reproducibility across shifts?
Through standardized SOP execution, automatic cleaning validation, temperature-stabilized transfer paths, and full electronic audit trails that capture every procedural parameter.
Can Xsample be retrofitted to existing DMA instruments?
Yes—Xsample units are field-upgradable to compatible DMA platforms manufactured from 2015 onward; firmware and mechanical interface kits are provided by Anton Paar Service Centers.