OHAUS Pioneer PX125DZH Analytical Balance

Overview

The OHAUS Pioneer PX125DZH is a high-precision analytical balance engineered for routine quantitative analysis in regulated and non-regulated laboratory environments. Operating on electromagnetic force compensation (EMFC) principle, it delivers stable, drift-compensated measurements with 0.01 mg readability across its 120 g maximum capacity. Designed to meet the functional and compliance expectations of QC laboratories, academic research facilities, and pharmaceutical manufacturing support labs, the PX125DZH integrates metrological rigor with ergonomic usability—without compromising structural integrity or long-term calibration stability. Its die-cast aluminum base provides mechanical damping against ambient vibrations, while the stainless steel pan and fully removable glass draft shield ensure chemical resistance and ease of cleaning—critical attributes for multi-user, high-throughput settings.

Key Features

• Electromagnetic force compensation sensor architecture delivering consistent 0.01 mg resolution and verified repeatability of ≤0.02 mg (standard deviation) under controlled conditions
• Dual-line LCD interface with contextual Chinese-language prompts—enabling intuitive operation without reliance on external documentation
• Integrated red ESD static elimination bar mounted above the weighing chamber, mitigating electrostatic interference during low-mass sample handling (e.g., powders, filter papers, micro-vials)
• Internal and external calibration modes compliant with ISO 4767 and ASTM E898-22; internal calibration uses motor-driven mass actuation with temperature-compensated reference weights
• GLP/GMP-ready firmware featuring real-time clock stamping, user-defined ID entry, and configurable data logging intervals
• Robust mechanical design: die-cast aluminum chassis, corrosion-resistant stainless steel pan, and optically clear tempered glass draft shield with quick-release mechanism
• Standard USB (virtual COM port) and RS232 interfaces supporting bidirectional communication with LIMS, ELN, and spreadsheet applications—fully compatible with OHAUS AC software and third-party drivers

Sample Compatibility & Compliance

The PX125DZH accommodates a broad range of sample forms—including solids, granules, lyophilized powders, and small-volume liquid containers—within its 120 g capacity and 190 mm × 190 mm pan footprint. Its draft shield assembly meets ISO 17025:2017 environmental control recommendations for Class II analytical balances. The instrument supports regulatory workflows aligned with FDA 21 CFR Part 11 (when used with validated software configurations), EU Annex 11, and ICH Q7 guidelines. Built-in environmental filtering allows dynamic adjustment of response time and noise suppression based on lab HVAC conditions—enhancing measurement robustness in variable thermal or airflow environments. Optional under-hook weighing capability extends functionality to density determination and magnetic susceptibility testing per ASTM D792 and ISO 1183.

Software & Data Management

Data export is supported via ASCII-formatted serial output (RS232) or HID-compliant USB mode, enabling seamless integration into validated laboratory informatics systems. The balance stores up to 999 measurement records locally with timestamps, operator IDs, and net/gross/tare flags. When connected to OHAUS AC Software (v3.0+), users can configure automated report generation, statistical process control (SPC) charts, and electronic signature capture—meeting ALCOA+ data integrity principles. Audit trail functionality logs all critical events: calibration actions, parameter changes, user logins, and error resets—retained for ≥30 days in non-volatile memory. Firmware updates are performed via USB drive, ensuring traceable version control per ISO/IEC 17025 clause 5.9.2.

Applications

• Pharmaceutical quality control: active pharmaceutical ingredient (API) assay, excipient blending verification, and reference standard preparation per USP and EP 2.1.6
• Academic research: stoichiometric reagent dispensing, catalyst loading quantification, and gravimetric moisture analysis (ASTM D2231)
• Materials science: powder density characterization, thin-film mass deposition monitoring, and nanomaterial dispersion quantification
• Environmental testing: filter weight gain analysis for PM2.5/PM10 particulate matter collection (EPA Method IO-3.2)
• Food safety labs: nutrient fortification verification, allergen cross-contamination assessment, and moisture content validation (AOAC 950.46)

FAQ

What is the minimum sample weight for reliable measurement on the PX125DZH?

The minimum weighable quantity (MWQ) is calculated as 2,000 × readability = 20 mg, assuming a typical repeatability of 0.01 mg and a required uncertainty ratio of 1:10 per USP .
Does the PX125DZH support automatic calibration triggered by temperature drift?

Yes—internal calibration initiates automatically when ambient temperature changes exceed ±1.5 °C from the last calibration point, provided Auto-Cal is enabled in setup mode.
Can the balance be integrated into a 21 CFR Part 11–compliant workflow?

When paired with validated third-party software (e.g., LabWare LIMS or Thermo Fisher SampleManager) and configured with user access controls, electronic signatures, and full audit trail export, the PX125DZH serves as a compliant data acquisition endpoint.
Is the glass draft shield certified for Class A cleanroom use?

The tempered glass shield meets ISO 14644-1 Class 5 particulate limits when cleaned using IPA-wiped lint-free wipes; however, full cleanroom certification requires site-specific validation per ISO 14644-3.
How is environmental filtering configured?

Three preset levels (Low/Medium/High) adjust digital filtering strength and settling time—accessible via Setup > Environmental Filter; selection depends on local vibration profile and air turbulence intensity.